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    v1.0.28
    OpenPayerBilling CodesProtozoal diseasesICD-10-CM b60-other-protozoal-diseases
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    ICD-10-CM Code For Other Protozoal Diseases Not Elsewhere Classified: Group Overview

    The International Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM) code group B60 includes protozoal infections not classified elsewhere, covering miscellaneous protozoan diseases that may affect the gastrointestinal tract, genitourinary tract, or cause systemic illness. These ICD-10-CM diagnosis codes are used to document clinical scenarios such as identified protozoal infections with uncommon organisms, atypical presentations, or infections that do not fit more specific protozoal categories, capturing disease severity, organ involvement, or clinical complexity relevant to this group. Accurate coding within the ICD-10-CM B60 group supports proper claim adjudication, complete clinical documentation, and appropriate reimbursement.

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    ICD-10-CM B60: Other Protozoal Diseases, Not Elsewhere Classified Overview

    This group includes protozoal infections that are not classified elsewhere and typically affect multiple organ systems depending on the organism. These diagnoses represent infections caused by protozoa that do not fit into more specific ICD-10-CM categories and may involve gastrointestinal, genitourinary, or systemic manifestations. Accurate coding matters for correct reimbursement and for reflecting the clinical complexity of the infection.

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    When to Use

    Use a code from this group when a protozoal infection is documented but does not meet criteria for a more specific protozoal diagnosis code elsewhere in ICD-10-CM. These codes apply when the organism is identified as a protozoan yet the presentation, site, or organism is not described in other dedicated protozoal categories.

    ICD-10-CM Codes

    12 rows

    ICD-10-CM CodeDescription
    B60.00Babesiosis, unspecified
    B60.01Babesiosis due to Babesia microti
    B60.02Babesiosis due to Babesia duncani
    B60.03Babesiosis due to Babesia divergens
    B60.09Other babesiosis
    B60.10Acanthamebiasis, unspecified
    B60.11Meningoencephalitis due to Acanthamoeba (culbertsoni)
    B60.12Conjunctivitis due to Acanthamoeba
    B60.13Keratoconjunctivitis due to Acanthamoeba
    B60.19Other acanthamebic disease
    B60.2Naegleriasis
    B60.8Other specified protozoal diseases

    DRG Codes

    8 rows

    DRG CodeDescription
    124Other Disorders of the Eye with MCC or Thrombolytic Agent
    125Other Disorders of the Eye without MCC
    867Other Infectious and Parasitic Diseases Diagnoses with MCC
    868Other Infectious and Parasitic Diseases Diagnoses with CC
    869Other Infectious and Parasitic Diseases Diagnoses without CC/MCC
    974HIV with Major Related Condition with MCC
    975HIV with Major Related Condition with CC
    976HIV with Major Related Condition without CC/MCC

    Typical Clinical Scenarios

    • An adult presents to the emergency department with high fever, severe headache, myalgia and rapidly progressive altered mental status after recent travel to a region endemic for free-living amoebae. CSF analysis and brain imaging suggest meningoencephalitis and laboratory testing later identifies infection with Naegleria fowleri or Acanthamoeba species; a code from this group is assigned for the acute, life‑threatening protozoal central nervous system infection. Typical codes: B60.00, B60.01
    • A middle‑aged patient with chronic granulomatous skin lesions and progressive focal neurologic deficits is evaluated in outpatient infectious disease clinic months after an indolent course; biopsy and culture indicate Acanthamoeba infection causing cutaneous and CNS involvement in an immunocompromised host. Because this represents a subacute to chronic protozoal disease requiring long‑term management and documentation of organ system involvement, a code from this group is used. Typical codes: B60.02, B60.03
    • A hospitalized immunosuppressed patient develops disseminated protozoal infection with pulmonary symptoms and systemic inflammatory response; laboratory testing identifies a less common protozoan species not classified elsewhere. The protozoal infection is listed as a complicating diagnosis that affects inpatient care and antibiotic/antiprotozoal selection, so a specific code from this group is assigned to capture the unusual protozoal etiology. Typical codes: B60.19, B60.8

    Related Codes

    B50-PLASMODIUM-FALCIPARUM-MALARIA

    ICD-10-CM Code For Plasmodium Falciparum Malaria: Group Overview

    B52-PLASMODIUM-MALARIAE-MALARIA

    ICD-10-CM Code For Plasmodium Malariae Malaria: Group Overview

    B53-OTHER-SPECIFIED-MALARIA

    ICD-10-CM Code For Other Specified Malaria: Group Overview

    B54-UNSPECIFIED-MALARIA

    ICD-10-CM Code For Unspecified Malaria: Group Overview

    B55-LEISHMANIASIS

    ICD-10-CM Code For Leishmaniasis: Group Overview

    B56-AFRICAN-TRYPANOSOMIASIS

    ICD-10-CM Code For African Trypanosomiasis: Group Overview

    B57-CHAGAS-DISEASE

    ICD-10-CM Code For Chagas' Disease: Group Overview

    B58-TOXOPLASMOSIS

    ICD-10-CM Code For Toxoplasmosis: Group Overview

    B59-PNEUMOCYSTOSIS

    ICD-10-CM Code For Pneumocystosis: Group Overview

    B64-UNSPECIFIED-PROTOZOAL-DISEASE

    ICD-10-CM Code For Unspecified Protozoal Disease: Group Overview

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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