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    OpenPayerBilling CodesProtozoal diseasesICD-10-CM b57-chagas-disease
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    ICD-10-CM Code For Chagas' Disease: Group Overview

    The International Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM) code group B57 includes diagnoses for Chagas' disease, covering acute Trypanosoma cruzi infection and chronic forms with cardiac or digestive complications. These ICD-10-CM diagnosis codes are used to document clinical scenarios that capture disease phase, organ involvement, and clinical complexity relevant to Chagas' disease. Accurate coding within the ICD-10-CM B57 group supports proper claim adjudication, complete clinical documentation, and appropriate reimbursement.

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    ICD-10-CM B57: Chagas' disease Overview

    The ICD-10-CM B57 group represents Chagas' disease, a protozoal infection caused by Trypanosoma cruzi that primarily affects the heart and gastrointestinal tract. These diagnoses target infectious and chronic complications such as acute infection, chronic indeterminate form, and cardiac and digestive involvement. Accurate coding matters for reimbursement because it captures disease severity, organ system involvement, and the need for specific monitoring or interventions.

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    When to Use

    Use a code from this group when a clinical encounter documents confirmed or suspected Chagas' disease or its specific complications such as cardiomyopathy or megaesophagus. Select the code that reflects the disease phase and the organ systems involved to accurately represent the clinical scenario.

    ICD-10-CM Codes

    12 rows

    ICD-10-CM CodeDescription
    B57.0Acute Chagas' disease with heart involvement
    B57.1Acute Chagas' disease without heart involvement
    B57.2Chagas' disease (chronic) with heart involvement
    B57.30Chagas' disease with digestive system involvement, unspecified
    B57.31Megaesophagus in Chagas' disease
    B57.32Megacolon in Chagas' disease
    B57.39Other digestive system involvement in Chagas' disease
    B57.40Chagas' disease with nervous system involvement, unspecified
    B57.41Meningitis in Chagas' disease
    B57.42Meningoencephalitis in Chagas' disease
    B57.49Other nervous system involvement in Chagas' disease
    B57.5Chagas' disease (chronic) with other organ involvement

    DRG Codes

    6 rows

    DRG CodeDescription
    314Other Circulatory System Diagnoses with MCC
    315Other Circulatory System Diagnoses with CC
    316Other Circulatory System Diagnoses without CC/MCC
    867Other Infectious and Parasitic Diseases Diagnoses with MCC
    868Other Infectious and Parasitic Diseases Diagnoses with CC
    869Other Infectious and Parasitic Diseases Diagnoses without CC/MCC

    Typical Clinical Scenarios

    • An adult patient from a rural Latin American region presents to the emergency department with weeks of progressive heart failure symptoms including exertional dyspnea, orthopnea, lower extremity edema, and palpitations; echocardiogram shows dilated cardiomyopathy and reduced ejection fraction, and history reveals prior untreated Trypanosoma cruzi infection. A Chagas-related chronic cardiac manifestation is assigned when cardiac involvement from the infection is documented as the cause of cardiomyopathy and heart failure. Typical codes: B57.0, B57.1
    • A middle-aged patient attending a tropical disease clinic reports years of gastrointestinal complaints with severe constipation, bloating, and unexplained weight loss; barium swallow and colon studies demonstrate megacolon and megaesophagus, and serology confirms chronic T. cruzi infection. A diagnosis from this group is used to capture chronic digestive system involvement secondary to Chagas disease when structural GI complications are present. Typical codes: B57.2, B57.30
    • An immunocompromised hospitalized patient (HIV-positive with low CD4) develops acute fever, new-onset myocarditis, and central nervous system signs with positive blood smear for Trypanosoma cruzi indicating acute reactivation. An acute, systemic parasitic infection or reactivation requiring inpatient management is coded from this group to reflect the active, severe presentation. Typical codes: B57.31, B57.39

    Related Codes

    B50-PLASMODIUM-FALCIPARUM-MALARIA

    ICD-10-CM Code For Plasmodium Falciparum Malaria: Group Overview

    B52-PLASMODIUM-MALARIAE-MALARIA

    ICD-10-CM Code For Plasmodium Malariae Malaria: Group Overview

    B53-OTHER-SPECIFIED-MALARIA

    ICD-10-CM Code For Other Specified Malaria: Group Overview

    B54-UNSPECIFIED-MALARIA

    ICD-10-CM Code For Unspecified Malaria: Group Overview

    B55-LEISHMANIASIS

    ICD-10-CM Code For Leishmaniasis: Group Overview

    B56-AFRICAN-TRYPANOSOMIASIS

    ICD-10-CM Code For African Trypanosomiasis: Group Overview

    B58-TOXOPLASMOSIS

    ICD-10-CM Code For Toxoplasmosis: Group Overview

    B59-PNEUMOCYSTOSIS

    ICD-10-CM Code For Pneumocystosis: Group Overview

    B60-OTHER-PROTOZOAL-DISEASES

    ICD-10-CM Code For Other Protozoal Diseases Not Elsewhere Classified: Group Overview

    B64-UNSPECIFIED-PROTOZOAL-DISEASE

    ICD-10-CM Code For Unspecified Protozoal Disease: Group Overview

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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