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    v1.0.28
    OpenPayerBilling CodesProtozoal diseasesICD-10-CM b59-pneumocystosis
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    ICD-10-CM Code For Pneumocystosis: Group Overview

    The International Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM) code group B59 includes infections caused by Pneumocystis species, primarily Pneumocystis jirovecii, presenting most commonly as pneumonia in immunocompromised hosts. These ICD-10-CM diagnosis codes are used to document clinical scenarios involving opportunistic pulmonary infection, including documentation of respiratory involvement and associated immunosuppression. Accurate coding within the ICD-10-CM B59 group supports proper claim adjudication, complete clinical documentation, and appropriate reimbursement.

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    ICD-10-CM B59: Pneumocystosis Overview

    Pneumocystosis diagnoses represent infections caused by the organism Pneumocystis, primarily affecting the respiratory system and often occurring in immunocompromised patients. Accurate coding captures the presence and clinical impact of these opportunistic infections and informs disease surveillance. Precise documentation supports correct claim processing and appropriate reimbursement tied to documented clinical severity.

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    When to Use

    Use a code from this group when a clinician documents pneumocystosis, such as Pneumocystis pneumonia, in the medical record with supporting clinical or laboratory evidence. Assign these codes to reflect the infection in patients with immunosuppression or other risk factors when it is the focus of care or treatment.

    ICD-10-CM Codes

    1 rows

    ICD-10-CM CodeDescription
    B59Pneumocystosis

    DRG Codes

    8 rows

    DRG CodeDescription
    177Respiratory Infections and Inflammations with MCC
    178Respiratory Infections and Inflammations with CC
    179Respiratory Infections and Inflammations without CC/MCC
    791Prematurity with Major Problems
    793Full Term Neonate with Major Problems
    974HIV with Major Related Condition with MCC
    975HIV with Major Related Condition with CC
    976HIV with Major Related Condition without CC/MCC

    Typical Clinical Scenarios

    • An immunocompromised adult with progressive dyspnea, nonproductive cough, and hypoxemia presents to the emergency department after several days of fever and worsening shortness of breath; chest imaging shows bilateral interstitial infiltrates and bronchoalveolar lavage demonstrates cysts consistent with Pneumocystis; a diagnosis from this group is assigned as the acute opportunistic pulmonary infection explaining the respiratory failure. Typical codes: B59
    • A patient with untreated HIV and a history of recurrent respiratory symptoms is evaluated in an infectious disease clinic for chronic exertional dyspnea and weight loss; prior sputum and induced sputum testing previously identified Pneumocystis organisms, and the clinician documents ongoing pneumocystosis as a chronic opportunistic infection contributing to the patient’s morbidity. Typical codes: B59
    • A hospitalized transplant recipient on prolonged immunosuppression develops new hypoxemia and diffuse pulmonary infiltrates during a post-operative stay; microbiologic testing from BAL confirms Pneumocystis and the infection is recorded as a significant comorbidity complicating the inpatient course and affecting treatment decisions. Typical codes: B59

    Related Codes

    B50-PLASMODIUM-FALCIPARUM-MALARIA

    ICD-10-CM Code For Plasmodium Falciparum Malaria: Group Overview

    B52-PLASMODIUM-MALARIAE-MALARIA

    ICD-10-CM Code For Plasmodium Malariae Malaria: Group Overview

    B53-OTHER-SPECIFIED-MALARIA

    ICD-10-CM Code For Other Specified Malaria: Group Overview

    B54-UNSPECIFIED-MALARIA

    ICD-10-CM Code For Unspecified Malaria: Group Overview

    B55-LEISHMANIASIS

    ICD-10-CM Code For Leishmaniasis: Group Overview

    B56-AFRICAN-TRYPANOSOMIASIS

    ICD-10-CM Code For African Trypanosomiasis: Group Overview

    B57-CHAGAS-DISEASE

    ICD-10-CM Code For Chagas' Disease: Group Overview

    B58-TOXOPLASMOSIS

    ICD-10-CM Code For Toxoplasmosis: Group Overview

    B60-OTHER-PROTOZOAL-DISEASES

    ICD-10-CM Code For Other Protozoal Diseases Not Elsewhere Classified: Group Overview

    B64-UNSPECIFIED-PROTOZOAL-DISEASE

    ICD-10-CM Code For Unspecified Protozoal Disease: Group Overview

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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