ICD-10-PCS Code For Left Lower Extremity: Procedure Code Group Overview

The International Classification of Diseases, Tenth Revision, Procedure Coding System (ICD-10-PCS) code group XHR7 includes procedures performed to replace skin and related materials in the left lower extremity. These ICD-10-PCS codes are used for inpatient documentation when a replacement of skin tissue with biological or synthetic material is performed on the left lower extremity. Accurate coding within the ICD-10-PCS XHR7 group is essential for proper inpatient reimbursement, as it captures the procedure performed and determines appropriate case mix and payment.

Customize your policy alerts

Sign up for ICD-10-PCS Code For Left Lower Extremity: Procedure Code Group Overview policy alerts

Get alerted when relevant policies change without checking for updates manually.

Monitor payer policy activity

Receive email alerts as soon as relevant payer policies are published or updated.

Left Lower Extremity Replacement Procedure Overview

This code group covers inpatient replacement procedures involving the skin of the left lower extremity, targeting the skin, subcutaneous tissue, fascia, and breast body system. Procedures involve placing biological or synthetic material that physically takes the place or function of the skin at the specified left lower extremity location. Accurate ICD-10-PCS coding ensures the procedure is captured for inpatient reimbursement and supports clinical documentation and case mix classification.

Code Attributes

Character	ICD-10-PCS Category	Code Group Details
X	Section	New Technology
H	Body System	Skin, Subcutaneous Tissue, Fascia and Breast
R	Operation	Replacement
7	Body Part	Skin, Left Lower Extremity

Explore openpayer tools

View all tools

ICD-10-PCS Code For Left Lower Extremity: Procedure Code Group Overview

Customize your policy alerts

Sign up for ICD-10-PCS Code For Left Lower Extremity: Procedure Code Group Overview policy alerts

Get alerted when relevant policies change without checking for updates manually.

Monitor payer policy activity

Receive email alerts as soon as relevant payer policies are published or updated.

Left Lower Extremity Replacement Procedure Overview

Code Attributes

Character	ICD-10-PCS Category	Code Group Details
X	Section	New Technology
H	Body System	Skin, Subcutaneous Tissue, Fascia and Breast
R	Operation	Replacement
7	Body Part	Skin, Left Lower Extremity

When to Use

Use a code from this group when the skin of the left lower extremity is replaced with materials that serve as a physical substitute for native skin during an inpatient encounter. Codes are assigned when the operation documented is Replacement and the body part is Skin, Left Lower Extremity.

ICD-10-PCS Codes

1 rows

ICD-10-PCS Code	Description
XHR7XGA	Replacement of Left Lower Extremity Skin with Prademagene Zamikeracel, Genetically Engineered Autologous Cell Therapy, External Approach, New Technology Group 10

DRG Codes

1 rows

DRG Code	Description
018	Chimeric Antigen Receptor (CAR) T-Cell and Other Immunotherapies

Typical Clinical Scenarios

A 45-year-old patient with a large, full-thickness traumatic degloving injury to the left lower leg and anterior ankle sustained in a motor vehicle collision requires inpatient surgical management. Native skin is nonviable over a substantial surface area and surgeons plan placement of an autologous, genetically engineered cell therapy graft to replace the damaged skin and restore coverage. The procedure is performed via an external approach during the inpatient admission to physically replace the left lower extremity skin and promote wound closure and healing. Typical codes: XHR7XGA
A 62-year-old patient with chronic, nonhealing venous stasis ulcers of the left lower leg refractory to conservative care is admitted electively for definitive surgical reconstruction. After debridement of scarred and nonviable tissue, clinicians place an autologous, genetically engineered cell therapy product to replace the diseased skin of the left lower extremity and facilitate durable wound closure. The inpatient procedure is planned and performed using an external application of the cell therapy as the replacement material. Typical codes: XHR7XGA
A 58-year-old patient previously treated with conventional split-thickness grafting to the left lower leg develops graft failure with exposed tendon and persistent breakdown; the patient is readmitted for revision coverage. Surgeons excise the failed graft and apply an autologous, genetically engineered cell therapy product externally to replace the skin layer over the affected left lower extremity and address the complication of prior graft loss. The operation documents replacement of left lower extremity skin using the specified cell therapy during the inpatient stay. Typical codes: XHR7XGA

Related Codes

XHR0-HEAD-AND-NECK-REPLACEMENT

ICD-10-PCS Code For Head And Neck: Procedure Code Group Overview

XHR1-CHEST-REPLACEMENT

ICD-10-PCS Code For Chest: Procedure Code Group Overview

XHR2-ABDOMEN-REPLACEMENT

ICD-10-PCS Code For Abdomen: Procedure Code Group Overview

XHR3-BACK-REPLACEMENT

ICD-10-PCS Code For Back: Procedure Code Group Overview

XHR4-RIGHT-UPPER-EXTREMITY-REPLACEMENT

ICD-10-PCS Code For Right Upper Extremity: Procedure Code Group Overview

XHR5-LEFT-UPPER-EXTREMITY-REPLACEMENT

ICD-10-PCS Code For Left Upper Extremity: Procedure Code Group Overview

XHR6-RIGHT-LOWER-EXTREMITY-REPLACEMENT

ICD-10-PCS Code For Right Lower Extremity: Procedure Code Group Overview

XHRP-SKIN-REPLACEMENT

ICD-10-PCS Code For Skin: Procedure Code Group Overview

Frequently Asked Questions

References

1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.

Published by

Trek Health powers OpenPayer with a leading commercial payer intelligence platform, seamlessly converting fragmented payer data into actionable insights for provider organizations.

Trek Health ingests and normalizes Transparency in Coverage data and payer policy updates to give provider organizations a clear view of how commercial reimbursement behaves across markets, payers, and services. Our platform transforms raw payer disclosures into structured intelligence that supports contract evaluation, payer negotiations, and service line strategy. By combining market benchmarks with ongoing policy visibility, Trek helps teams identify variability, risk, and opportunity in commercial reimbursement. The result is faster insight, stronger negotiating positions, and more informed financial decisions.

Explore openpayer tools

View all tools

When to Use

ICD-10-PCS Codes

1 rows

ICD-10-PCS Code	Description
XHR7XGA	Replacement of Left Lower Extremity Skin with Prademagene Zamikeracel, Genetically Engineered Autologous Cell Therapy, External Approach, New Technology Group 10

DRG Codes

1 rows

DRG Code	Description
018	Chimeric Antigen Receptor (CAR) T-Cell and Other Immunotherapies

Typical Clinical Scenarios

A 45-year-old patient with a large, full-thickness traumatic degloving injury to the left lower leg and anterior ankle sustained in a motor vehicle collision requires inpatient surgical management. Native skin is nonviable over a substantial surface area and surgeons plan placement of an autologous, genetically engineered cell therapy graft to replace the damaged skin and restore coverage. The procedure is performed via an external approach during the inpatient admission to physically replace the left lower extremity skin and promote wound closure and healing. Typical codes: XHR7XGA
A 62-year-old patient with chronic, nonhealing venous stasis ulcers of the left lower leg refractory to conservative care is admitted electively for definitive surgical reconstruction. After debridement of scarred and nonviable tissue, clinicians place an autologous, genetically engineered cell therapy product to replace the diseased skin of the left lower extremity and facilitate durable wound closure. The inpatient procedure is planned and performed using an external application of the cell therapy as the replacement material. Typical codes: XHR7XGA
A 58-year-old patient previously treated with conventional split-thickness grafting to the left lower leg develops graft failure with exposed tendon and persistent breakdown; the patient is readmitted for revision coverage. Surgeons excise the failed graft and apply an autologous, genetically engineered cell therapy product externally to replace the skin layer over the affected left lower extremity and address the complication of prior graft loss. The operation documents replacement of left lower extremity skin using the specified cell therapy during the inpatient stay. Typical codes: XHR7XGA

Related Codes

XHR0-HEAD-AND-NECK-REPLACEMENT

ICD-10-PCS Code For Head And Neck: Procedure Code Group Overview

XHR1-CHEST-REPLACEMENT

ICD-10-PCS Code For Chest: Procedure Code Group Overview

XHR2-ABDOMEN-REPLACEMENT

ICD-10-PCS Code For Abdomen: Procedure Code Group Overview

XHR3-BACK-REPLACEMENT

ICD-10-PCS Code For Back: Procedure Code Group Overview

XHR4-RIGHT-UPPER-EXTREMITY-REPLACEMENT

ICD-10-PCS Code For Right Upper Extremity: Procedure Code Group Overview

XHR5-LEFT-UPPER-EXTREMITY-REPLACEMENT

ICD-10-PCS Code For Left Upper Extremity: Procedure Code Group Overview

XHR6-RIGHT-LOWER-EXTREMITY-REPLACEMENT

ICD-10-PCS Code For Right Lower Extremity: Procedure Code Group Overview

XHRP-SKIN-REPLACEMENT

ICD-10-PCS Code For Skin: Procedure Code Group Overview

Frequently Asked Questions

References

1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.

Published by

Trek Health powers OpenPayer with a leading commercial payer intelligence platform, seamlessly converting fragmented payer data into actionable insights for provider organizations.

ICD-10-PCS Code For Left Lower Extremity: Procedure Code Group Overview

Sign up for ICD-10-PCS Code For Left Lower Extremity: Procedure Code Group Overview policy alerts

Left Lower Extremity Replacement Procedure Overview

Code Attributes

ICD-10-PCS Code For Left Lower Extremity: Procedure Code Group Overview

Sign up for ICD-10-PCS Code For Left Lower Extremity: Procedure Code Group Overview policy alerts

Left Lower Extremity Replacement Procedure Overview

Code Attributes

When to Use

ICD-10-PCS Codes

DRG Codes

Typical Clinical Scenarios

Related Codes

What is the focus of the ICD-10-PCS code group XHR7?

Which specific ICD-10-PCS code in this group represents replacement with Prademagene Zamikeracel?

What section and body system attributes apply to these codes?

How does accurate coding within the XHR7 group affect reimbursement?

Are there related DRGs linked to the XHR7 code group?

References

When to Use

ICD-10-PCS Codes

DRG Codes

Typical Clinical Scenarios

Related Codes

What is the focus of the ICD-10-PCS code group XHR7?

Which specific ICD-10-PCS code in this group represents replacement with Prademagene Zamikeracel?

What section and body system attributes apply to these codes?

How does accurate coding within the XHR7 group affect reimbursement?

Are there related DRGs linked to the XHR7 code group?

References