ICD-10-PCS Code For Left Upper Extremity: Procedure Code Group Overview

The International Classification of Diseases, Tenth Revision, Procedure Coding System (ICD-10-PCS) code group XHR5 includes procedures performed to replace skin and related structures in the left upper extremity. These ICD-10-PCS codes are used for inpatient documentation when a portion or all of the left upper extremity skin is replaced with biological or synthetic material via an external approach. Accurate coding within the ICD-10-PCS XHR5 group is essential for proper inpatient reimbursement, as it captures the procedure performed and determines appropriate case mix and payment.

Customize your policy alerts

Sign up for ICD-10-PCS Code For Left Upper Extremity: Procedure Code Group Overview policy alerts

Get alerted when relevant policies change without checking for updates manually.

Monitor payer policy activity

Receive email alerts as soon as relevant payer policies are published or updated.

Left Upper Extremity Replacement Procedure Overview

Procedures in this group involve replacement of skin on the left upper extremity and target the skin, subcutaneous tissue, fascia, and related structures. These operations replace all or part of the skin with biological or synthetic material delivered via an external approach and are classified in the New Technology section of the International Classification of Diseases, Tenth Revision, Procedure Coding System (ICD-10-PCS). Accurate coding ensures the inpatient record reflects the specific replacement procedure performed and supports appropriate case mix assignment and reimbursement.

Code Attributes

Character	ICD-10-PCS Category	Code Group Details
X	Section	New Technology
H	Body System	Skin, Subcutaneous Tissue, Fascia and Breast
R	Operation	Replacement
5	Body Part	Skin, Left Upper Extremity

Explore openpayer tools

View all tools

ICD-10-PCS Code For Left Upper Extremity: Procedure Code Group Overview

Customize your policy alerts

Sign up for ICD-10-PCS Code For Left Upper Extremity: Procedure Code Group Overview policy alerts

Get alerted when relevant policies change without checking for updates manually.

Monitor payer policy activity

Receive email alerts as soon as relevant payer policies are published or updated.

Left Upper Extremity Replacement Procedure Overview

Code Attributes

Character	ICD-10-PCS Category	Code Group Details
X	Section	New Technology
H	Body System	Skin, Subcutaneous Tissue, Fascia and Breast
R	Operation	Replacement
5	Body Part	Skin, Left Upper Extremity

When to Use

Use a code from this group when the clinical procedure replaces all or part of the left upper extremity skin with an implant or graft delivered externally. These codes apply when the operation performed is Replacement as defined in ICD-10-PCS and the body system is Skin, Subcutaneous Tissue, Fascia and Breast.

ICD-10-PCS Codes

1 rows

ICD-10-PCS Code	Description
XHR5XGA	Replacement of Left Upper Extremity Skin with Prademagene Zamikeracel, Genetically Engineered Autologous Cell Therapy, External Approach, New Technology Group 10

DRG Codes

1 rows

DRG Code	Description
018	Chimeric Antigen Receptor (CAR) T-Cell and Other Immunotherapies

Typical Clinical Scenarios

An adult patient with a large, full-thickness degloving injury to the left forearm and dorsal hand after a motor vehicle collision is admitted for staged wound management and definitive soft tissue coverage. Because the native skin is nonviable over an extensive area and limb preservation is the goal, the surgical team replaces the damaged left upper extremity skin with an autologous, genetically engineered cell therapy graft to restore barrier function and promote healing; inpatient care is required for postoperative monitoring and dressing changes. Typical codes: XHR5XGA
An elderly patient with chronic, nonhealing left forearm skin loss over irradiated tissue and recurrent ulceration presents for planned reconstructive surgery after failed conservative care. The elective inpatient procedure uses a novel autologous, genetically engineered cell replacement to reconstruct the left upper extremity skin where prior grafts and local flaps were unsuccessful, with admission for perioperative optimization and specialized wound care. Typical codes: XHR5XGA
A middle-aged patient develops an extensive infected necrosis of left arm skin following a complex burn treated initially at an outpatient burn center; after debridement and control of sepsis, the patient is taken to the operating room for replacement of the left upper extremity skin with a genetically engineered autologous cell therapy implant as part of a revision reconstructive plan. Inpatient care continues for infection surveillance, graft take assessment, and rehabilitation. Typical codes: XHR5XGA

Related Codes

XHR0-HEAD-AND-NECK-REPLACEMENT

ICD-10-PCS Code For Head And Neck: Procedure Code Group Overview

XHR1-CHEST-REPLACEMENT

ICD-10-PCS Code For Chest: Procedure Code Group Overview

XHR2-ABDOMEN-REPLACEMENT

ICD-10-PCS Code For Abdomen: Procedure Code Group Overview

XHR3-BACK-REPLACEMENT

ICD-10-PCS Code For Back: Procedure Code Group Overview

XHR4-RIGHT-UPPER-EXTREMITY-REPLACEMENT

ICD-10-PCS Code For Right Upper Extremity: Procedure Code Group Overview

XHR6-RIGHT-LOWER-EXTREMITY-REPLACEMENT

ICD-10-PCS Code For Right Lower Extremity: Procedure Code Group Overview

XHR7-LEFT-LOWER-EXTREMITY-REPLACEMENT

ICD-10-PCS Code For Left Lower Extremity: Procedure Code Group Overview

XHRP-SKIN-REPLACEMENT

ICD-10-PCS Code For Skin: Procedure Code Group Overview

Frequently Asked Questions

References

1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.

Published by

Trek Health powers OpenPayer with a leading commercial payer intelligence platform, seamlessly converting fragmented payer data into actionable insights for provider organizations.

Trek Health ingests and normalizes Transparency in Coverage data and payer policy updates to give provider organizations a clear view of how commercial reimbursement behaves across markets, payers, and services. Our platform transforms raw payer disclosures into structured intelligence that supports contract evaluation, payer negotiations, and service line strategy. By combining market benchmarks with ongoing policy visibility, Trek helps teams identify variability, risk, and opportunity in commercial reimbursement. The result is faster insight, stronger negotiating positions, and more informed financial decisions.

Explore openpayer tools

View all tools

When to Use

ICD-10-PCS Codes

1 rows

ICD-10-PCS Code	Description
XHR5XGA	Replacement of Left Upper Extremity Skin with Prademagene Zamikeracel, Genetically Engineered Autologous Cell Therapy, External Approach, New Technology Group 10

DRG Codes

1 rows

DRG Code	Description
018	Chimeric Antigen Receptor (CAR) T-Cell and Other Immunotherapies

Typical Clinical Scenarios

An adult patient with a large, full-thickness degloving injury to the left forearm and dorsal hand after a motor vehicle collision is admitted for staged wound management and definitive soft tissue coverage. Because the native skin is nonviable over an extensive area and limb preservation is the goal, the surgical team replaces the damaged left upper extremity skin with an autologous, genetically engineered cell therapy graft to restore barrier function and promote healing; inpatient care is required for postoperative monitoring and dressing changes. Typical codes: XHR5XGA
An elderly patient with chronic, nonhealing left forearm skin loss over irradiated tissue and recurrent ulceration presents for planned reconstructive surgery after failed conservative care. The elective inpatient procedure uses a novel autologous, genetically engineered cell replacement to reconstruct the left upper extremity skin where prior grafts and local flaps were unsuccessful, with admission for perioperative optimization and specialized wound care. Typical codes: XHR5XGA
A middle-aged patient develops an extensive infected necrosis of left arm skin following a complex burn treated initially at an outpatient burn center; after debridement and control of sepsis, the patient is taken to the operating room for replacement of the left upper extremity skin with a genetically engineered autologous cell therapy implant as part of a revision reconstructive plan. Inpatient care continues for infection surveillance, graft take assessment, and rehabilitation. Typical codes: XHR5XGA

Related Codes

XHR0-HEAD-AND-NECK-REPLACEMENT

ICD-10-PCS Code For Head And Neck: Procedure Code Group Overview

XHR1-CHEST-REPLACEMENT

ICD-10-PCS Code For Chest: Procedure Code Group Overview

XHR2-ABDOMEN-REPLACEMENT

ICD-10-PCS Code For Abdomen: Procedure Code Group Overview

XHR3-BACK-REPLACEMENT

ICD-10-PCS Code For Back: Procedure Code Group Overview

XHR4-RIGHT-UPPER-EXTREMITY-REPLACEMENT

ICD-10-PCS Code For Right Upper Extremity: Procedure Code Group Overview

XHR6-RIGHT-LOWER-EXTREMITY-REPLACEMENT

ICD-10-PCS Code For Right Lower Extremity: Procedure Code Group Overview

XHR7-LEFT-LOWER-EXTREMITY-REPLACEMENT

ICD-10-PCS Code For Left Lower Extremity: Procedure Code Group Overview

XHRP-SKIN-REPLACEMENT

ICD-10-PCS Code For Skin: Procedure Code Group Overview

Frequently Asked Questions

References

1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.

Published by

Trek Health powers OpenPayer with a leading commercial payer intelligence platform, seamlessly converting fragmented payer data into actionable insights for provider organizations.

ICD-10-PCS Code For Left Upper Extremity: Procedure Code Group Overview

Sign up for ICD-10-PCS Code For Left Upper Extremity: Procedure Code Group Overview policy alerts

Left Upper Extremity Replacement Procedure Overview

Code Attributes

ICD-10-PCS Code For Left Upper Extremity: Procedure Code Group Overview

Sign up for ICD-10-PCS Code For Left Upper Extremity: Procedure Code Group Overview policy alerts

Left Upper Extremity Replacement Procedure Overview

Code Attributes

When to Use

ICD-10-PCS Codes

DRG Codes

Typical Clinical Scenarios

Related Codes

Which ICD-10-PCS code represents replacement of left upper extremity skin with Prademagene Zamikeracel?

What body system and operation are specified for codes in the XHR5 group?

For what clinical situations are XHR5 group codes used in inpatient records?

How does accurate coding within the XHR5 group impact hospital billing?

Which related DRG is associated with procedures in this code group?

References

When to Use

ICD-10-PCS Codes

DRG Codes

Typical Clinical Scenarios

Related Codes

Which ICD-10-PCS code represents replacement of left upper extremity skin with Prademagene Zamikeracel?

What body system and operation are specified for codes in the XHR5 group?

For what clinical situations are XHR5 group codes used in inpatient records?

How does accurate coding within the XHR5 group impact hospital billing?

Which related DRG is associated with procedures in this code group?

References