ICD-10-PCS Code For Head And Neck: Procedure Code Group Overview

The International Classification of Diseases, Tenth Revision, Procedure Coding System (ICD-10-PCS) code group XHR0 includes procedures performed to replace skin in the head and neck. These ICD-10-PCS codes are used for inpatient documentation when a patient receives biologic or synthetic material to take the place and/or function of all or part of the head and neck skin. Accurate coding within the ICD-10-PCS XHR0 group is essential for proper inpatient reimbursement, as it captures the procedure performed and determines appropriate case mix and payment.

Customize your policy alerts

Sign up for ICD-10-PCS Code For Head And Neck: Procedure Code Group Overview policy alerts

Get alerted when relevant policies change without checking for updates manually.

Monitor payer policy activity

Receive email alerts as soon as relevant payer policies are published or updated.

Head And Neck Replacement Procedure Overview

Procedures in this group involve replacement of skin on the head and neck and target the Skin, Subcutaneous Tissue, Fascia and Breast body system. These operations place biological material that physically takes the place and/or function of all or a portion of the skin in the head and neck region. Accurate ICD-10-PCS coding is important for inpatient reimbursement because it documents the specific replacement procedure performed and supports appropriate case mix assignment and payment.

Code Attributes

Character	ICD-10-PCS Category	Code Group Details
X	Section	New Technology
H	Body System	Skin, Subcutaneous Tissue, Fascia and Breast
R	Operation	Replacement
0	Body Part	Skin, Head and Neck

Explore openpayer tools

View all tools

ICD-10-PCS Code For Head And Neck: Procedure Code Group Overview

Customize your policy alerts

Sign up for ICD-10-PCS Code For Head And Neck: Procedure Code Group Overview policy alerts

Get alerted when relevant policies change without checking for updates manually.

Monitor payer policy activity

Receive email alerts as soon as relevant payer policies are published or updated.

Head And Neck Replacement Procedure Overview

Code Attributes

Character	ICD-10-PCS Category	Code Group Details
X	Section	New Technology
H	Body System	Skin, Subcutaneous Tissue, Fascia and Breast
R	Operation	Replacement
0	Body Part	Skin, Head and Neck

When to Use

Use a code from this group when the operative intent is replacement of all or a portion of head and neck skin with a material that substitutes for the skin s function. These codes apply when the replacement is performed via an external approach and is documented in the inpatient record.

ICD-10-PCS Codes

1 rows

ICD-10-PCS Code	Description
XHR0XGA	Replacement of Head and Neck Skin with Prademagene Zamikeracel, Genetically Engineered Autologous Cell Therapy, External Approach, New Technology Group 10

DRG Codes

1 rows

DRG Code	Description
018	Chimeric Antigen Receptor (CAR) T-Cell and Other Immunotherapies

Typical Clinical Scenarios

A 45-year-old patient is admitted urgently after a major thermal burn involving full-thickness loss of skin across portions of the face and scalp with exposed subcutaneous tissue. Because autologous grafts are insufficient and the goal is durable replacement of the lost skin to restore barrier function and promote healing, the operative plan is to place a genetically engineered autologous cell therapy product that will physically replace the damaged skin of the head and neck via an external approach. The procedure is performed during the inpatient stay to manage acute wound coverage and reduce risk of infection and fluid loss. Typical codes: XHR0XGA
A 62-year-old patient with extensive post-oncologic surgical defects of the cheek and periauricular skin after resection of a cutaneous malignancy is scheduled for a planned inpatient reconstructive procedure. The surgical team intends to reconstruct and replace the missing head and neck skin using the patient’s genetically engineered autologous cell therapy product applied externally to restore skin continuity and function. The procedure is elective but performed in the hospital for multidisciplinary postoperative monitoring. Typical codes: XHR0XGA
A 38-year-old patient with a chronic nonhealing complex facial wound previously treated with standard grafting presents for revision because prior grafts failed and there is ongoing exposure and scarring causing functional impairment. The care plan is to excise devitalized tissue and replace the defective head and neck skin with a genetically engineered autologous cell therapy product applied externally to achieve durable coverage and improve wound healing. This inpatient revision procedure addresses the complication of graft failure and aims to restore tissue integrity. Typical codes: XHR0XGA

Related Codes

XHR1-CHEST-REPLACEMENT

ICD-10-PCS Code For Chest: Procedure Code Group Overview

XHR2-ABDOMEN-REPLACEMENT

ICD-10-PCS Code For Abdomen: Procedure Code Group Overview

XHR3-BACK-REPLACEMENT

ICD-10-PCS Code For Back: Procedure Code Group Overview

XHR4-RIGHT-UPPER-EXTREMITY-REPLACEMENT

ICD-10-PCS Code For Right Upper Extremity: Procedure Code Group Overview

XHR5-LEFT-UPPER-EXTREMITY-REPLACEMENT

ICD-10-PCS Code For Left Upper Extremity: Procedure Code Group Overview

XHR6-RIGHT-LOWER-EXTREMITY-REPLACEMENT

ICD-10-PCS Code For Right Lower Extremity: Procedure Code Group Overview

XHR7-LEFT-LOWER-EXTREMITY-REPLACEMENT

ICD-10-PCS Code For Left Lower Extremity: Procedure Code Group Overview

XHRP-SKIN-REPLACEMENT

ICD-10-PCS Code For Skin: Procedure Code Group Overview

Frequently Asked Questions

References

1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.

Published by

Trek Health powers OpenPayer with a leading commercial payer intelligence platform, seamlessly converting fragmented payer data into actionable insights for provider organizations.

Trek Health ingests and normalizes Transparency in Coverage data and payer policy updates to give provider organizations a clear view of how commercial reimbursement behaves across markets, payers, and services. Our platform transforms raw payer disclosures into structured intelligence that supports contract evaluation, payer negotiations, and service line strategy. By combining market benchmarks with ongoing policy visibility, Trek helps teams identify variability, risk, and opportunity in commercial reimbursement. The result is faster insight, stronger negotiating positions, and more informed financial decisions.

Explore openpayer tools

View all tools

When to Use

ICD-10-PCS Codes

1 rows

ICD-10-PCS Code	Description
XHR0XGA	Replacement of Head and Neck Skin with Prademagene Zamikeracel, Genetically Engineered Autologous Cell Therapy, External Approach, New Technology Group 10

DRG Codes

1 rows

DRG Code	Description
018	Chimeric Antigen Receptor (CAR) T-Cell and Other Immunotherapies

Typical Clinical Scenarios

A 45-year-old patient is admitted urgently after a major thermal burn involving full-thickness loss of skin across portions of the face and scalp with exposed subcutaneous tissue. Because autologous grafts are insufficient and the goal is durable replacement of the lost skin to restore barrier function and promote healing, the operative plan is to place a genetically engineered autologous cell therapy product that will physically replace the damaged skin of the head and neck via an external approach. The procedure is performed during the inpatient stay to manage acute wound coverage and reduce risk of infection and fluid loss. Typical codes: XHR0XGA
A 62-year-old patient with extensive post-oncologic surgical defects of the cheek and periauricular skin after resection of a cutaneous malignancy is scheduled for a planned inpatient reconstructive procedure. The surgical team intends to reconstruct and replace the missing head and neck skin using the patient’s genetically engineered autologous cell therapy product applied externally to restore skin continuity and function. The procedure is elective but performed in the hospital for multidisciplinary postoperative monitoring. Typical codes: XHR0XGA
A 38-year-old patient with a chronic nonhealing complex facial wound previously treated with standard grafting presents for revision because prior grafts failed and there is ongoing exposure and scarring causing functional impairment. The care plan is to excise devitalized tissue and replace the defective head and neck skin with a genetically engineered autologous cell therapy product applied externally to achieve durable coverage and improve wound healing. This inpatient revision procedure addresses the complication of graft failure and aims to restore tissue integrity. Typical codes: XHR0XGA

Related Codes

XHR1-CHEST-REPLACEMENT

ICD-10-PCS Code For Chest: Procedure Code Group Overview

XHR2-ABDOMEN-REPLACEMENT

ICD-10-PCS Code For Abdomen: Procedure Code Group Overview

XHR3-BACK-REPLACEMENT

ICD-10-PCS Code For Back: Procedure Code Group Overview

XHR4-RIGHT-UPPER-EXTREMITY-REPLACEMENT

ICD-10-PCS Code For Right Upper Extremity: Procedure Code Group Overview

XHR5-LEFT-UPPER-EXTREMITY-REPLACEMENT

ICD-10-PCS Code For Left Upper Extremity: Procedure Code Group Overview

XHR6-RIGHT-LOWER-EXTREMITY-REPLACEMENT

ICD-10-PCS Code For Right Lower Extremity: Procedure Code Group Overview

XHR7-LEFT-LOWER-EXTREMITY-REPLACEMENT

ICD-10-PCS Code For Left Lower Extremity: Procedure Code Group Overview

XHRP-SKIN-REPLACEMENT

ICD-10-PCS Code For Skin: Procedure Code Group Overview

Frequently Asked Questions

References

1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.

Published by

Trek Health powers OpenPayer with a leading commercial payer intelligence platform, seamlessly converting fragmented payer data into actionable insights for provider organizations.

ICD-10-PCS Code For Head And Neck: Procedure Code Group Overview

Sign up for ICD-10-PCS Code For Head And Neck: Procedure Code Group Overview policy alerts

Head And Neck Replacement Procedure Overview

Code Attributes

ICD-10-PCS Code For Head And Neck: Procedure Code Group Overview

Sign up for ICD-10-PCS Code For Head And Neck: Procedure Code Group Overview policy alerts

Head And Neck Replacement Procedure Overview

Code Attributes

When to Use

ICD-10-PCS Codes

DRG Codes

Typical Clinical Scenarios

Related Codes

Which ICD-10-PCS code is used for replacement of head and neck skin with Prademagene Zamikeracel?

What body system and operation does the XHR0 code group represent?

Why is accurate coding in the XHR0 group important for inpatient care?

What code attributes are used to classify `XHR0XGA`?

Which related DRG is associated with the XHR0 code group in the provided content?

References

When to Use

ICD-10-PCS Codes

DRG Codes

Typical Clinical Scenarios

Related Codes

Which ICD-10-PCS code is used for replacement of head and neck skin with Prademagene Zamikeracel?

What body system and operation does the XHR0 code group represent?

Why is accurate coding in the XHR0 group important for inpatient care?

What code attributes are used to classify `XHR0XGA`?

Which related DRG is associated with the XHR0 code group in the provided content?

References