ICD-10-PCS Code For Right Lower Extremity: Procedure Code Group Overview

The International Classification of Diseases, Tenth Revision, Procedure Coding System (ICD-10-PCS) code group XHR6 includes procedures performed to replace skin and related tissues in the right lower extremity. These ICD-10-PCS codes are used for inpatient documentation when a material or graft is implanted or applied to substitute for skin function on the right lower extremity. Accurate coding within the ICD-10-PCS XHR6 group is essential for proper inpatient reimbursement, as it captures the procedure performed and supports clinical documentation accuracy.

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Right Lower Extremity Replacement Procedure Overview

This group includes inpatient procedures that replace all or part of the skin of the right lower extremity using biological or synthetic materials, targeting the skin, subcutaneous tissue, fascia, and breast body system. These procedures involve implanting or applying materials that physically take the place and/or function of skin on the right lower leg or foot. Accurate ICD-10-PCS coding is important for correct inpatient reimbursement and for reflecting the clinical work performed in the medical record.

Code Attributes

Character	ICD-10-PCS Category	Code Group Details
X	Section	New Technology
H	Body System	Skin, Subcutaneous Tissue, Fascia and Breast
R	Operation	Replacement
6	Body Part	Skin, Right Lower Extremity

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ICD-10-PCS Code For Right Lower Extremity: Procedure Code Group Overview

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Right Lower Extremity Replacement Procedure Overview

Code Attributes

Character	ICD-10-PCS Category	Code Group Details
X	Section	New Technology
H	Body System	Skin, Subcutaneous Tissue, Fascia and Breast
R	Operation	Replacement
6	Body Part	Skin, Right Lower Extremity

When to Use

Use a code from this group when the clinical procedure replaces all or part of the right lower extremity skin with an implanted or applied material intended to assume skin function. Select the specific ICD-10-PCS code in this group based on the material type and approach documented in the operative record.

ICD-10-PCS Codes

1 rows

ICD-10-PCS Code	Description
XHR6XGA	Replacement of Right Lower Extremity Skin with Prademagene Zamikeracel, Genetically Engineered Autologous Cell Therapy, External Approach, New Technology Group 10

DRG Codes

1 rows

DRG Code	Description
018	Chimeric Antigen Receptor (CAR) T-Cell and Other Immunotherapies

Typical Clinical Scenarios

A middle-aged patient with a large full-thickness burn involving the anterior and lateral skin of the right lower leg after a thermal injury is admitted for definitive wound coverage once the wound bed is prepared and infection is controlled; because the procedure replaces damaged skin with a biologic, autologous cell–based graft designed to restore skin function on the right lower extremity, an inpatient replacement procedure is performed. Typical codes: XHR6XGA
An elderly diabetic patient with a nonhealing, full-thickness right lower extremity ulcer that has failed conservative therapy and local flap attempts is taken to the operating room for planned implantation of a genetically engineered autologous skin cell therapy to replace the diseased skin and promote durable closure; this elective inpatient procedure targets the right lower extremity skin to restore coverage and function. Typical codes: XHR6XGA
A patient presents with an infected, grafted area on the right lower leg after prior reconstruction; after debridement and control of infection, the surgeon replaces the failed surface graft with a new application of autologous, genetically engineered cell therapy to re-establish skin integrity on the right lower extremity during the same inpatient admission. Typical codes: XHR6XGA

Related Codes

XHR0-HEAD-AND-NECK-REPLACEMENT

ICD-10-PCS Code For Head And Neck: Procedure Code Group Overview

XHR1-CHEST-REPLACEMENT

ICD-10-PCS Code For Chest: Procedure Code Group Overview

XHR2-ABDOMEN-REPLACEMENT

ICD-10-PCS Code For Abdomen: Procedure Code Group Overview

XHR3-BACK-REPLACEMENT

ICD-10-PCS Code For Back: Procedure Code Group Overview

XHR4-RIGHT-UPPER-EXTREMITY-REPLACEMENT

ICD-10-PCS Code For Right Upper Extremity: Procedure Code Group Overview

XHR5-LEFT-UPPER-EXTREMITY-REPLACEMENT

ICD-10-PCS Code For Left Upper Extremity: Procedure Code Group Overview

XHR7-LEFT-LOWER-EXTREMITY-REPLACEMENT

ICD-10-PCS Code For Left Lower Extremity: Procedure Code Group Overview

XHRP-SKIN-REPLACEMENT

ICD-10-PCS Code For Skin: Procedure Code Group Overview

Frequently Asked Questions

References

1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.

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When to Use

ICD-10-PCS Codes

1 rows

ICD-10-PCS Code	Description
XHR6XGA	Replacement of Right Lower Extremity Skin with Prademagene Zamikeracel, Genetically Engineered Autologous Cell Therapy, External Approach, New Technology Group 10

DRG Codes

1 rows

DRG Code	Description
018	Chimeric Antigen Receptor (CAR) T-Cell and Other Immunotherapies

Typical Clinical Scenarios

A middle-aged patient with a large full-thickness burn involving the anterior and lateral skin of the right lower leg after a thermal injury is admitted for definitive wound coverage once the wound bed is prepared and infection is controlled; because the procedure replaces damaged skin with a biologic, autologous cell–based graft designed to restore skin function on the right lower extremity, an inpatient replacement procedure is performed. Typical codes: XHR6XGA
An elderly diabetic patient with a nonhealing, full-thickness right lower extremity ulcer that has failed conservative therapy and local flap attempts is taken to the operating room for planned implantation of a genetically engineered autologous skin cell therapy to replace the diseased skin and promote durable closure; this elective inpatient procedure targets the right lower extremity skin to restore coverage and function. Typical codes: XHR6XGA
A patient presents with an infected, grafted area on the right lower leg after prior reconstruction; after debridement and control of infection, the surgeon replaces the failed surface graft with a new application of autologous, genetically engineered cell therapy to re-establish skin integrity on the right lower extremity during the same inpatient admission. Typical codes: XHR6XGA

Related Codes

XHR0-HEAD-AND-NECK-REPLACEMENT

ICD-10-PCS Code For Head And Neck: Procedure Code Group Overview

XHR1-CHEST-REPLACEMENT

ICD-10-PCS Code For Chest: Procedure Code Group Overview

XHR2-ABDOMEN-REPLACEMENT

ICD-10-PCS Code For Abdomen: Procedure Code Group Overview

XHR3-BACK-REPLACEMENT

ICD-10-PCS Code For Back: Procedure Code Group Overview

XHR4-RIGHT-UPPER-EXTREMITY-REPLACEMENT

ICD-10-PCS Code For Right Upper Extremity: Procedure Code Group Overview

XHR5-LEFT-UPPER-EXTREMITY-REPLACEMENT

ICD-10-PCS Code For Left Upper Extremity: Procedure Code Group Overview

XHR7-LEFT-LOWER-EXTREMITY-REPLACEMENT

ICD-10-PCS Code For Left Lower Extremity: Procedure Code Group Overview

XHRP-SKIN-REPLACEMENT

ICD-10-PCS Code For Skin: Procedure Code Group Overview

Frequently Asked Questions

References

1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.

Published by

Trek Health powers OpenPayer with a leading commercial payer intelligence platform, seamlessly converting fragmented payer data into actionable insights for provider organizations.

ICD-10-PCS Code For Right Lower Extremity: Procedure Code Group Overview

Sign up for ICD-10-PCS Code For Right Lower Extremity: Procedure Code Group Overview policy alerts

Right Lower Extremity Replacement Procedure Overview

Code Attributes

ICD-10-PCS Code For Right Lower Extremity: Procedure Code Group Overview

Sign up for ICD-10-PCS Code For Right Lower Extremity: Procedure Code Group Overview policy alerts

Right Lower Extremity Replacement Procedure Overview

Code Attributes

When to Use

ICD-10-PCS Codes

DRG Codes

Typical Clinical Scenarios

Related Codes

Which ICD-10-PCS code represents replacement of right lower extremity skin with Prademagene Zamikeracel?

What body system and operation does the XHR6 code group describe?

For what inpatient documentation purpose is accurate coding within the XHR6 group important?

What anatomical site does `XHR6XGA` specifically apply to?

Which related DRG is associated with this procedure group?

References

When to Use

ICD-10-PCS Codes

DRG Codes

Typical Clinical Scenarios

Related Codes

Which ICD-10-PCS code represents replacement of right lower extremity skin with Prademagene Zamikeracel?

What body system and operation does the XHR6 code group describe?

For what inpatient documentation purpose is accurate coding within the XHR6 group important?

What anatomical site does `XHR6XGA` specifically apply to?

Which related DRG is associated with this procedure group?

References