ICD-10-PCS Code For Right Upper Extremity: Procedure Code Group Overview

The International Classification of Diseases, Tenth Revision, Procedure Coding System (ICD-10-PCS) code group XHR4 includes procedures performed to replace skin in the right upper extremity. These ICD-10-PCS codes are used for inpatient documentation when biologic or synthetic material is put in or on the skin to take the place and/or function of all or a portion of the right upper extremity skin. Accurate coding within the ICD-10-PCS XHR4 group is essential for proper inpatient reimbursement, as it captures the procedure performed and determines appropriate case mix and payment.

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Right Upper Extremity Replacement Procedure Overview

This procedure group covers replacement procedures involving the skin of the right upper extremity within the Skin, Subcutaneous Tissue, Fascia and Breast body system. These procedures involve putting in or on biological or synthetic material that physically takes the place and/or function of all or a portion of the skin. Accurate ICD-10-PCS coding ensures inpatient records reflect the correct replacement operation and supports appropriate reimbursement and case mix assignment.

Code Attributes

Character	ICD-10-PCS Category	Code Group Details
X	Section	New Technology
H	Body System	Skin, Subcutaneous Tissue, Fascia and Breast
R	Operation	Replacement
4	Body Part	Skin, Right Upper Extremity

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ICD-10-PCS Code For Right Upper Extremity: Procedure Code Group Overview

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Right Upper Extremity Replacement Procedure Overview

Code Attributes

Character	ICD-10-PCS Category	Code Group Details
X	Section	New Technology
H	Body System	Skin, Subcutaneous Tissue, Fascia and Breast
R	Operation	Replacement
4	Body Part	Skin, Right Upper Extremity

When to Use

Use a code from this group when a procedure replaces all or a portion of the right upper extremity skin with implanted or applied biological or synthetic material. Select the specific code when the documentation supports an external approach replacement and the operation is replacement of the skin.

ICD-10-PCS Codes

1 rows

ICD-10-PCS Code	Description
XHR4XGA	Replacement of Right Upper Extremity Skin with Prademagene Zamikeracel, Genetically Engineered Autologous Cell Therapy, External Approach, New Technology Group 10

DRG Codes

1 rows

DRG Code	Description
018	Chimeric Antigen Receptor (CAR) T-Cell and Other Immunotherapies

Typical Clinical Scenarios

A middle-aged patient with a large full-thickness degloving injury of the right forearm and dorsal hand after a motor vehicle collision requires inpatient surgical management for extensive soft tissue loss; after debridement and stabilization, replacement of the right upper extremity skin with a genetically engineered autologous cell therapy is performed to restore skin coverage and promote healing. Typical codes: XHR4XGA
An elderly diabetic patient with a chronic, non-healing right forearm ulcer with exposed fascia and failed prior grafts is admitted for definitive reconstruction; because local options are exhausted and autologous engineered cell therapy is indicated to replace the diseased right upper extremity skin, the procedure is performed via an external approach during the inpatient stay. Typical codes: XHR4XGA
A patient presents after prior mesh and synthetic graft failure with recurrent breakdown of the right upper arm skin over an exposed tendon, resulting in infection and need for revision; inpatient replacement of the right upper extremity skin using a genetically engineered autologous cell therapy is undertaken to remove failed material and reconstruct the skin barrier. Typical codes: XHR4XGA

Related Codes

XHR0-HEAD-AND-NECK-REPLACEMENT

ICD-10-PCS Code For Head And Neck: Procedure Code Group Overview

XHR1-CHEST-REPLACEMENT

ICD-10-PCS Code For Chest: Procedure Code Group Overview

XHR2-ABDOMEN-REPLACEMENT

ICD-10-PCS Code For Abdomen: Procedure Code Group Overview

XHR3-BACK-REPLACEMENT

ICD-10-PCS Code For Back: Procedure Code Group Overview

XHR5-LEFT-UPPER-EXTREMITY-REPLACEMENT

ICD-10-PCS Code For Left Upper Extremity: Procedure Code Group Overview

XHR6-RIGHT-LOWER-EXTREMITY-REPLACEMENT

ICD-10-PCS Code For Right Lower Extremity: Procedure Code Group Overview

XHR7-LEFT-LOWER-EXTREMITY-REPLACEMENT

ICD-10-PCS Code For Left Lower Extremity: Procedure Code Group Overview

XHRP-SKIN-REPLACEMENT

ICD-10-PCS Code For Skin: Procedure Code Group Overview

Frequently Asked Questions

References

1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.

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When to Use

ICD-10-PCS Codes

1 rows

ICD-10-PCS Code	Description
XHR4XGA	Replacement of Right Upper Extremity Skin with Prademagene Zamikeracel, Genetically Engineered Autologous Cell Therapy, External Approach, New Technology Group 10

DRG Codes

1 rows

DRG Code	Description
018	Chimeric Antigen Receptor (CAR) T-Cell and Other Immunotherapies

Typical Clinical Scenarios

A middle-aged patient with a large full-thickness degloving injury of the right forearm and dorsal hand after a motor vehicle collision requires inpatient surgical management for extensive soft tissue loss; after debridement and stabilization, replacement of the right upper extremity skin with a genetically engineered autologous cell therapy is performed to restore skin coverage and promote healing. Typical codes: XHR4XGA
An elderly diabetic patient with a chronic, non-healing right forearm ulcer with exposed fascia and failed prior grafts is admitted for definitive reconstruction; because local options are exhausted and autologous engineered cell therapy is indicated to replace the diseased right upper extremity skin, the procedure is performed via an external approach during the inpatient stay. Typical codes: XHR4XGA
A patient presents after prior mesh and synthetic graft failure with recurrent breakdown of the right upper arm skin over an exposed tendon, resulting in infection and need for revision; inpatient replacement of the right upper extremity skin using a genetically engineered autologous cell therapy is undertaken to remove failed material and reconstruct the skin barrier. Typical codes: XHR4XGA

Related Codes

XHR0-HEAD-AND-NECK-REPLACEMENT

ICD-10-PCS Code For Head And Neck: Procedure Code Group Overview

XHR1-CHEST-REPLACEMENT

ICD-10-PCS Code For Chest: Procedure Code Group Overview

XHR2-ABDOMEN-REPLACEMENT

ICD-10-PCS Code For Abdomen: Procedure Code Group Overview

XHR3-BACK-REPLACEMENT

ICD-10-PCS Code For Back: Procedure Code Group Overview

XHR5-LEFT-UPPER-EXTREMITY-REPLACEMENT

ICD-10-PCS Code For Left Upper Extremity: Procedure Code Group Overview

XHR6-RIGHT-LOWER-EXTREMITY-REPLACEMENT

ICD-10-PCS Code For Right Lower Extremity: Procedure Code Group Overview

XHR7-LEFT-LOWER-EXTREMITY-REPLACEMENT

ICD-10-PCS Code For Left Lower Extremity: Procedure Code Group Overview

XHRP-SKIN-REPLACEMENT

ICD-10-PCS Code For Skin: Procedure Code Group Overview

Frequently Asked Questions

References

1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.

Published by

Trek Health powers OpenPayer with a leading commercial payer intelligence platform, seamlessly converting fragmented payer data into actionable insights for provider organizations.

ICD-10-PCS Code For Right Upper Extremity: Procedure Code Group Overview

Sign up for ICD-10-PCS Code For Right Upper Extremity: Procedure Code Group Overview policy alerts

Right Upper Extremity Replacement Procedure Overview

Code Attributes

ICD-10-PCS Code For Right Upper Extremity: Procedure Code Group Overview

Sign up for ICD-10-PCS Code For Right Upper Extremity: Procedure Code Group Overview policy alerts

Right Upper Extremity Replacement Procedure Overview

Code Attributes

When to Use

ICD-10-PCS Codes

DRG Codes

Typical Clinical Scenarios

Related Codes

Which ICD-10-PCS code group covers replacement of right upper extremity skin?

What is the specific code for replacement with Prademagene Zamikeracel?

Which body system and operation are represented by the XHR4 code group?

How does accurate coding in the XHR4 group affect inpatient care documentation?

Are there related DRGs associated with XHR4 procedures?

References

When to Use

ICD-10-PCS Codes

DRG Codes

Typical Clinical Scenarios

Related Codes

Which ICD-10-PCS code group covers replacement of right upper extremity skin?

What is the specific code for replacement with Prademagene Zamikeracel?

Which body system and operation are represented by the XHR4 code group?

How does accurate coding in the XHR4 group affect inpatient care documentation?

Are there related DRGs associated with XHR4 procedures?

References