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    OpenPayerBilling CodesSystemic connective tissue disordersICD-10-CM m36-systemic-connective-tissue-disorders
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    ICD-10-CM Code For Systemic Disorders Of Connective Tissue In Diseases Classified Elsewhere: Group Overview

    The International Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM) code group M36 includes systemic connective tissue disorders that occur in diseases classified elsewhere, such as connective tissue involvement secondary to infectious, neoplastic, or endocrine diseases. These ICD-10-CM diagnosis codes are used to document multisystem connective tissue involvement, capturing disease severity, organ involvement, or clinical complexity relevant to this group. Accurate coding within the ICD-10-CM M36 group supports proper claim adjudication, complete clinical documentation, and appropriate reimbursement.

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    ICD-10-CM M36: Systemic Disorders Of Connective Tissue In Diseases Classified Elsewhere Overview

    This group captures systemic connective tissue disorders that occur in the context of other classified diseases, affecting multiple organ systems through autoimmune or rheumatologic mechanisms. It targets disorders where connective tissue involvement is a consequence of another underlying condition rather than a primary rheumatologic disease. Accurate coding ensures clinical severity and organ involvement are documented, which supports correct claim processing and appropriate reimbursement.

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    When to Use

    Use a code from this group when a patient has documented connective tissue involvement that is explicitly attributed to a disease classified elsewhere in the International Classification of Diseases, Tenth Revision, Clinical Modification. These codes are appropriate when clinical documentation links connective tissue manifestations to the primary underlying condition and when coding requires specifying that secondary relationship.

    ICD-10-CM Codes

    6 rows

    ICD-10-CM CodeDescription
    M36.0Dermato(poly)myositis in neoplastic disease
    M36.1Arthropathy in neoplastic disease
    M36.2Hemophilic arthropathy
    M36.3Arthropathy in other blood disorders
    M36.4Arthropathy in hypersensitivity reactions classified elsewhere
    M36.8Systemic disorders of connective tissue in other diseases classified elsewhere

    DRG Codes

    5 rows

    DRG CodeDescription
    545Connective Tissue Disorders with MCC
    546Connective Tissue Disorders with CC
    547Connective Tissue Disorders without CC/MCC
    553Bone Diseases and Arthropathies with MCC
    554Bone Diseases and Arthropathies without MCC

    Typical Clinical Scenarios

    • An adult patient with long-standing systemic lupus erythematosus presents to the rheumatology clinic with new-onset diffuse skin tightening, sclerodactyly, and interstitial lung disease confirmed on high-resolution CT. The clinician documents that these are systemic connective tissue manifestations occurring in the course of the underlying systemic autoimmune disease, prompting assignment of a connective tissue disorder code from this group. Typical codes: M36.0, M36.1
    • An elderly patient is admitted through the emergency department for acute renal failure and hypertensive crisis found to be secondary to a flare of systemic vasculitis previously diagnosed as a connective tissue disorder; the inpatient team documents multisystem involvement (kidney and skin) attributed to the known systemic connective tissue disease. Because the organ dysfunction is directly related to the underlying connective tissue disorder classified elsewhere, a code from this group is assigned to capture the systemic complication. Typical codes: M36.3, M36.4
    • A pediatric patient with a history of juvenile dermatomyositis is seen for routine follow-up for chronic muscle weakness and calcinosis limiting function; the visit focuses on ongoing management of the systemic connective tissue disease and its chronic sequelae rather than a new acute illness. For documentation of the chronic systemic connective tissue disorder manifesting in muscle and skin, an appropriate code from this group is used. Typical codes: M36.2, M36.8

    Related Codes

    M30-POLYARTERITIS-NODOSA-AND-RELATED-CONDITIONS

    ICD-10-CM Code For Polyarteritis Nodosa And Related Conditions: Group Overview

    M31-OTHER-NECROTIZING-VASCULOPATHIES

    ICD-10-CM Code For Other Necrotizing Vasculopathies: Group Overview

    M32-SYSTEMIC-LUPUS-ERYTHEMATOSUS

    ICD-10-CM Code For Systemic Lupus Erythematosus SLE: Group Overview

    M33-DERMATOPOLYMYOSITIS-CONDITIONS

    ICD-10-CM Code For Dermatopolymyositis: Group Overview

    M34-SYSTEMIC-SCLEROSIS-SCLERODERMA

    ICD-10-CM Code For Systemic Sclerosis [Scleroderma]: Group Overview

    M35-OTHER-SYSTEMIC-INVOLVEMENT-OF-CONNECTIVE-TISSUE

    ICD-10-CM Code For Other Systemic Involvement Of Connective Tissue: Group Overview

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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