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    v1.0.28
    OpenPayerBilling CodesDiseases and Disorders of the Musculoskeletal System and Connective TissueDRG 547-connective-tissue-disorders-without-cc-mcc
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    Connective Tissue Disorders without CC/MCC: Inpatient Reimbursement Overview

    DRG 547 groups inpatient stays for connective tissue disorders without Complication or Comorbidity or Major Complication or Comorbidity, defining a lower-severity payment category. It matters for inpatient reimbursement because assignment to this Diagnosis-Related Group establishes the baseline Medicare payment and reflects clinical and coding specificity.

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    DRG 547 Overview

    DRG 547 covers inpatient admissions for connective tissue disorders without Complication or Comorbidity or Major Complication or Comorbidity, including conditions such as uncomplicated systemic connective tissue diseases and isolated inflammatory or degenerative soft tissue disorders. This category groups patients whose primary diagnoses do not trigger higher-severity payment adjustments, making it relevant for baseline payment determination. Coding specificity and accurate principal diagnosis assignment influence assignment to this Diagnosis-Related Group, which affects Medicare inpatient reimbursement. Facilities and coders use this group to classify lower-severity connective tissue admissions for payment and reporting purposes.

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    Clinical Trials

    • Studies of early inpatient diagnostic algorithms and biomarker panels for acute presentations of connective tissue disorders: trials testing structured approaches to rapidly differentiate inflammatory connective tissue flares (eg, polymyalgia rheumatica-like syndromes, inflammatory myopathies, vasculitis) from noninflammatory mimics in patients admitted for pain, weakness, or systemic features. These studies enroll hospitalized adults who present with acute constitutional symptoms, elevated inflammatory markers, or new organ dysfunction and evaluate speed and accuracy of diagnosis, impact on length of stay, and resource utilization; results inform clinicians and payers about optimal workup pathways to reduce unnecessary testing and shorten admissions.
    • Comparative effectiveness trials of inpatient immunomodulatory strategies for moderate disease without major complications: pragmatic studies comparing alternative corticosteroid-sparing approaches, dosing strategies, or adjunctive therapies in patients admitted with active connective tissue disease manifestations that do not meet criteria for major complications (no CC/MCC). These trials focus on commonly encountered hospitalized patients to determine which regimens improve symptom control, reduce hospital days, and minimize short-term adverse events, providing evidence that can guide hospital formulary decisions and reimbursement policy for standard-of-care therapies.
    • Post-discharge outcomes and care-transition studies assessing readmission risk, functional recovery, and outpatient management pathways: observational cohorts and interventional trials that follow patients discharged after admissions for connective tissue disorders without major complications to evaluate rates and causes of readmission, adherence to follow-up rheumatology care, rehabilitation needs, and patient-reported outcomes. This research targets the subacute recovery phase to identify high-risk patients who would benefit from targeted discharge planning or outpatient care coordination, offering payers data on interventions that may reduce readmissions and downstream costs.

    Related Codes

    402-SINGLE-LEVEL-COMBINED-ANTERIOR-AND-POSTERIOR-SPINAL-FUSION-EXCEPT-CERVICAL

    Single Level Combined Anterior and Posterior Spinal Fusion Except Cervical: Inpatient Reimbursement Overview

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    Multiple Level Combined Anterior and Posterior Spinal Fusion Except Cervical with MCC or Custom-Made Anatomically Designed Interbody Fusion Device: Inpatient Reimbursement Overview

    427-MULTIPLE-LEVEL-COMBINED-ANTERIOR-AND-POSTERIOR-SPINAL-FUSION-EXCEPT-CERVICAL-WITH-CC

    Multiple Level Combined Anterior and Posterior Spinal Fusion Except Cervical with CC: Inpatient Reimbursement Overview

    428-MULTIPLE-LEVEL-COMBINED-ANTERIOR-AND-POSTERIOR-SPINAL-FUSION-EXCEPT-CERVICAL-WITHOUT-CC-MCC

    Multiple Level Combined Anterior and Posterior Spinal Fusion Except Cervical without CC/MCC: Inpatient Reimbursement Overview

    429-COMBINED-ANTERIOR-AND-POSTERIOR-CERVICAL-SPINAL-FUSION-WITH-MCC

    Combined Anterior and Posterior Cervical Spinal Fusion with MCC: Inpatient Reimbursement Overview

    430-COMBINED-ANTERIOR-AND-POSTERIOR-CERVICAL-SPINAL-FUSION-WITHOUT-MCC

    Combined Anterior and Posterior Cervical Spinal Fusion without MCC: Inpatient Reimbursement Overview

    447-MULTIPLE-LEVEL-SPINAL-FUSION-EXCEPT-CERVICAL-WITH-MCC-OR-CUSTOM-MADE-ANATOMICALLY-DESIGNED-INTERBODY-FUSION-DEVICE

    Multiple Level Spinal Fusion Except Cervical with MCC: Inpatient Reimbursement Overview

    448-MULTIPLE-LEVEL-SPINAL-FUSION-EXCEPT-CERVICAL-WITHOUT-MCC

    Multiple Level Spinal Fusion Except Cervical without MCC: Inpatient Reimbursement Overview

    450-SINGLE-LEVEL-SPINAL-FUSION-EXCEPT-CERVICAL-WITH-MCC-OR-CUSTOM-MADE-ANATOMICALLY-DESIGNED-INTERBODY-FUSION-DEVICE

    Single Level Spinal Fusion Except Cervical with MCC or Custom-Made Device: Inpatient Reimbursement Overview

    451-SINGLE-LEVEL-SPINAL-FUSION-EXCEPT-CERVICAL-WITHOUT-MCC

    Single Level Spinal Fusion Except Cervical without MCC: Inpatient Reimbursement Overview

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    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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