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    OpenPayerBilling CodesSystemic connective tissue disordersICD-10-CM m32-systemic-lupus-erythematosus
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    ICD-10-CM Code For Systemic Lupus Erythematosus SLE: Group Overview

    The International Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM) code group M32 includes diagnoses for systemic lupus erythematosus and its specified manifestations, covering acute and chronic forms as well as organ-specific involvement such as lupus nephritis and neurologic lupus. These ICD-10-CM diagnosis codes are used to document disease activity, organ system complications, and the presence of specific clinical manifestations that affect treatment and monitoring. Accurate coding within the ICD-10-CM M32 group supports proper claim adjudication, complete clinical documentation, and appropriate reimbursement.

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    ICD-10-CM M32: Systemic Lupus Erythematosus (SLE) Overview

    The ICD-10-CM M32 group includes diagnoses for systemic lupus erythematosus, an autoimmune systemic connective tissue disorder that can affect skin, joints, kidneys, nervous system, and other organs. These codes represent varying manifestations and complications of the disease, including organ-specific involvement and activity. Accurate coding is important to reflect clinical complexity and to support appropriate reimbursement and care coordination.

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    When to Use

    Use a code from this group when a clinical assessment documents systemic lupus erythematosus or a specified manifestation of lupus that requires coding for diagnosis, treatment, or monitoring. Codes from this group are applied to reflect disease activity, organ involvement, or complications that impact clinical management and billing.

    ICD-10-CM Codes

    10 rows

    ICD-10-CM CodeDescription
    M32.0Drug-induced systemic lupus erythematosus
    M32.10Systemic lupus erythematosus, organ or system involvement unspecified
    M32.11Endocarditis in systemic lupus erythematosus
    M32.12Pericarditis in systemic lupus erythematosus
    M32.13Lung involvement in systemic lupus erythematosus
    M32.14Glomerular disease in systemic lupus erythematosus
    M32.15Tubulo-interstitial nephropathy in systemic lupus erythematosus
    M32.19Other organ or system involvement in systemic lupus erythematosus
    M32.8Other forms of systemic lupus erythematosus
    M32.9Systemic lupus erythematosus, unspecified

    DRG Codes

    3 rows

    DRG CodeDescription
    545Connective Tissue Disorders with MCC
    546Connective Tissue Disorders with CC
    547Connective Tissue Disorders without CC/MCC

    Typical Clinical Scenarios

    • A young adult woman presents to the emergency department with acute onset of high fever, pleuritic chest pain, shortness of breath, and a malar rash after several days of fatigue and arthralgias. Workup shows serologic markers consistent with active systemic autoimmune disease and chest imaging consistent with pleuritis; she requires inpatient management for an acute flare of systemic lupus. A diagnosis from this group is assigned to describe active systemic lupus with multisystem involvement during this acute presentation. Typical codes: M32.10, M32.0
    • A middle-aged patient is followed in rheumatology clinic for chronic systemic autoimmune disease characterized by longstanding photosensitive rashes, nonerosive inflammatory arthritis, and intermittent low-grade proteinuria monitored over years. The visit documents routine disease maintenance, medication management, and surveillance for organ involvement; a code from this group is used to indicate the underlying chronic systemic lupus diagnosis. Typical codes: M32.9, M32.11
    • An adult with known systemic autoimmune disease is admitted for evaluation of new-onset nephrotic-range proteinuria and rising creatinine; renal biopsy confirms lupus nephritis requiring escalation of immunosuppressive therapy. The hospitalization codes the systemic disease as the underlying cause of the renal complication and assigns a code from this group to reflect systemic lupus with major organ (renal) involvement. Typical codes: M32.14, M32.12

    Related Codes

    M30-POLYARTERITIS-NODOSA-AND-RELATED-CONDITIONS

    ICD-10-CM Code For Polyarteritis Nodosa And Related Conditions: Group Overview

    M31-OTHER-NECROTIZING-VASCULOPATHIES

    ICD-10-CM Code For Other Necrotizing Vasculopathies: Group Overview

    M33-DERMATOPOLYMYOSITIS-CONDITIONS

    ICD-10-CM Code For Dermatopolymyositis: Group Overview

    M34-SYSTEMIC-SCLEROSIS-SCLERODERMA

    ICD-10-CM Code For Systemic Sclerosis [Scleroderma]: Group Overview

    M35-OTHER-SYSTEMIC-INVOLVEMENT-OF-CONNECTIVE-TISSUE

    ICD-10-CM Code For Other Systemic Involvement Of Connective Tissue: Group Overview

    M36-SYSTEMIC-CONNECTIVE-TISSUE-DISORDERS

    ICD-10-CM Code For Systemic Disorders Of Connective Tissue In Diseases Classified Elsewhere: Group Overview

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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