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    OpenPayerBilling CodesMetabolic disordersICD-10-CM e87-other-fluid-electrolyte-disorders
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    ICD-10-CM Code For Other Disorders Of Fluid Electrolyte And Acid-Base Balance: Group Overview

    The International Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM) code group E87 includes disorders of fluid, electrolyte and acid-base balance such as dehydration, hyponatremia, hypernatremia, hypokalemia, hyperkalemia, metabolic acidosis, and metabolic alkalosis that capture disturbances in serum electrolytes and systemic acid-base status. These ICD-10-CM diagnosis codes are used to document clinical scenarios involving electrolyte imbalances, volume depletion or overload, and acid-base disorders that affect treatment decisions and monitoring needs. Accurate coding within the ICD-10-CM E87 group supports proper claim adjudication, complete clinical documentation, and appropriate reimbursement.

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    ICD-10-CM E87: Other Disorders Of Fluid, Electrolyte And Acid-Base Balance Overview

    This group represents disturbances in body fluids, electrolytes, and acid-base homeostasis affecting multiple organ systems, including renal, endocrine, and metabolic pathways. Accurate coding of these conditions is important because fluid and electrolyte abnormalities can significantly affect patient management and length of stay. Precise documentation and coding support correct reimbursement and reflect clinical complexity.

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    When to Use

    Use a code from this group when a patient has a documented electrolyte disturbance, fluid-volume disorder, or acid-base imbalance that requires clinical attention, monitoring, or treatment. Select the most specific code that reflects the documented abnormality, its severity if specified, and any associated clinical context such as dehydration or renal dysfunction.

    ICD-10-CM Codes

    14 rows

    ICD-10-CM CodeDescription
    E87.0Hyperosmolality and hypernatremia
    E87.1Hypo-osmolality and hyponatremia
    E87.20Acidosis, unspecified
    E87.21Acute metabolic acidosis
    E87.22Chronic metabolic acidosis
    E87.29Other acidosis
    E87.3Alkalosis
    E87.4Mixed disorder of acid-base balance
    E87.5Hyperkalemia
    E87.6Hypokalemia
    E87.70Fluid overload, unspecified
    E87.71Transfusion associated circulatory overload
    E87.79Other fluid overload
    E87.8Other disorders of electrolyte and fluid balance, not elsewhere classified

    DRG Codes

    4 rows

    DRG CodeDescription
    640Miscellaneous Disorders of Nutrition, Metabolism, Fluids and Electrolytes with MCC
    641Miscellaneous Disorders of Nutrition, Metabolism, Fluids and Electrolytes without MCC
    791Prematurity with Major Problems
    793Full Term Neonate with Major Problems

    Typical Clinical Scenarios

    • Elderly patient with acute confusion, lethargy, and decreased urine output after several days of vomiting and poor oral intake; laboratory tests show serum sodium of 128 mEq/L and low serum osmolality, indicating dilutional hyponatremia from volume depletion and free water excess. This acute presentation to the emergency department leads to assignment of a sodium disorder code to guide immediate fluid and electrolyte management. Typical codes: E87.1, E87.0.
    • Middle-aged patient with chronic congestive heart failure followed in clinic who develops progressive peripheral edema and documented hypervolemia with low serum sodium on routine labs despite diuretic therapy; the hyponatremia is recognized as a chronic comorbidity complicating management of the underlying cardiac disease. A code from this group is used to capture the electrolyte disturbance as a chronic complication affecting outpatient treatment decisions. Typical codes: E87.1, E87.7.
    • Hospitalized postoperative patient who becomes hypotensive and oliguric after major abdominal surgery; labs reveal metabolic acidosis with serum bicarbonate decrease and an elevated anion gap, consistent with an acute acid–base disorder related to tissue hypoperfusion. The acid–base imbalance is documented with an appropriate code from this group to reflect the acute metabolic disturbance complicating the inpatient course. Typical codes: E87.2, E87.3.

    Related Codes

    E70-DISORDERS-OF-AROMATIC-AMINO-ACID-METABOLISM

    ICD-10-CM Code For Disorders Of Aromatic Amino-Acid Metabolism: Group Overview

    E71-DISORDERS-OF-BRANCHED-CHAIN-AMINO-ACID-METABOLISM

    ICD-10-CM Code For Disorders Of Branched Chain Amino Acid Metabolism And Fatty Acid Metabolism: Group Overview

    E72-OTHER-DISORDERS-OF-AMINO-ACID-METABOLISM

    ICD-10-CM Code For Other Disorders Of Amino-Acid Metabolism: Group Overview

    E73-LACTOSE-INTOLERANCE

    ICD-10-CM Code For Lactose Intolerance: Group Overview

    E74-OTHER-DISORDERS-OF-CARBOHYDRATE-METABOLISM

    ICD-10-CM Code For Other Disorders Of Carbohydrate Metabolism: Group Overview

    E75-DISORDERS-OF-SPHINGOLIPID-METABOLISM

    ICD-10-CM Code For Disorders Of Sphingolipid Metabolism And Other Lipid Storage Disorders: Group Overview

    E76-DISORDERS-OF-GLYCOSAMINOGLYCAN-METABOLISM

    ICD-10-CM Code For Disorders Of Glycosaminoglycan Metabolism: Group Overview

    E77-DISORDERS-OF-GLYCOPROTEIN-METABOLISM

    ICD-10-CM Code For Disorders Of Glycoprotein Metabolism: Group Overview

    E78-DISORDERS-OF-LIPOPROTEIN-METABOLISM

    ICD-10-CM Code For Disorders Of Lipoprotein Metabolism And Other Lipidemias: Group Overview

    E79-DISORDERS-OF-PURINE-AND-PYRIMIDINE-METABOLISM

    ICD-10-CM Code For Disorders Of Purine And Pyrimidine Metabolism: Group Overview

    Showing 1–10 of 16

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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