Loading...

    Explore
    • Policy Monitoring
    • Live Policy Feed
    • Billing Codes
    • NPI Medicare & Medicaid
    • Healthcare Providers
    • Health Insurance Payers
    • States
    • Service Lines
    • Taxonomy Codes
    Lookup tools
    • Billing Code Lookup
    • CPT Modifier Lookup
    • Provider Taxonomy Code Lookup
    • Healthcare Provider & Facility Lookup
    • Health Insurance Payer Lookup
    • Payer Contact Directory

    Policy & Benchmark Tools

    • Prior Authorization Lookup
    • Coverage Criteria Lookup
    • Timely Filing Lookup
    • Billing Code Reimbursement Rates
    • Payer Comparison Dashboard
    • Facility Comparison Dashboard
    • All tools

    Company

    • About OpenPayer
    • Data Sources
    • Trek Health
    OpenPayerby Trek Health
    LinkedInYouTube

    © 2026 Trek Health. All rights reserved.

    OpenPayer is built and maintained by Trek Health.

    v1.0.28
    OpenPayerBilling CodesMetabolic disordersICD-10-CM e74-other-disorders-of-carbohydrate-metabolism
    Ask Trek AI about this page

    ICD-10-CM Code For Other Disorders Of Carbohydrate Metabolism: Group Overview

    The International Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM) code group E74 includes disorders of carbohydrate metabolism such as glycogen storage diseases, fructose intolerance, galactosemia, and other specific enzyme deficiencies that impair carbohydrate processing. These ICD-10-CM diagnosis codes are used to document clinical presentations including recurrent hypoglycemia, failure to thrive, hepatomegaly, and other organ involvement or metabolic decompensation indicating disease severity. Accurate coding within the ICD-10-CM E74 group supports appropriate reimbursement, complete clinical documentation, and proper claim adjudication.

    Customize your policy alerts

    Sign up for ICD-10-CM Code For Other Disorders Of Carbohydrate Metabolism: Group Overview policy alerts

    Get alerted when relevant policies change without checking for updates manually.

    Monitor payer policy activity

    Receive email alerts as soon as relevant payer policies are published or updated.

    ICD-10-CM E74: Other Disorders Of Carbohydrate Metabolism Overview

    This group represents inherited and acquired disorders that affect carbohydrate metabolism, including conditions that impair glycogen storage, fructose and galactose metabolism, and other enzymatic defects. These diagnoses target metabolic and endocrine systems with systemic clinical effects ranging from hypoglycemia to organ dysfunction. Accurate coding matters for reimbursement because it ensures claims reflect clinical complexity and supports correct payment and medical record clarity.

    Table of contents

    Progress1 / 6

    Explore openpayer tools

    • Billing CodesCPT, HCPCS, DRG & more
    • Reimbursement RatesCommercial vs. Medicare rate reports
    • ProvidersHospitals & facilities
    • PayersPlans & market footprint
    • Taxonomy CodesNUCC specialty codes
    • ModifiersCPT modifiers & usage
    • Prior AuthorizationPA policies by payer & drug
    • Timely FilingFiling deadlines by payer
    • Coverage CriteriaMedical necessity by payer
    • Payer ContactsClaims, PA & appeals contacts
    View all tools

    When to Use

    Use a code from this group when clinical evaluation documents a specific carbohydrate metabolism disorder or enzyme deficiency such as glycogen storage disease, hereditary fructose intolerance, or galactosemia. Apply the most specific code available that reflects the confirmed diagnosis, associated complications, and current clinical status.

    ICD-10-CM Codes

    24 rows

    ICD-10-CM CodeDescription
    E74.00Glycogen storage disease, unspecified
    E74.01von Gierke disease
    E74.02Pompe disease
    E74.03Cori disease
    E74.04McArdle disease
    E74.05Lysosome-associated membrane protein 2 [LAMP2] deficiency
    E74.09Other glycogen storage disease
    E74.10Disorder of fructose metabolism, unspecified
    E74.11Essential fructosuria
    E74.12Hereditary fructose intolerance
    E74.19Other disorders of fructose metabolism
    E74.20Disorders of galactose metabolism, unspecified
    E74.21Galactosemia
    E74.29Other disorders of galactose metabolism
    E74.31Sucrase-isomaltase deficiency
    E74.39Other disorders of intestinal carbohydrate absorption
    E74.4Disorders of pyruvate metabolism and gluconeogenesis
    E74.810Glucose transporter protein type 1 deficiency
    E74.818Other disorders of glucose transport
    E74.819Disorders of glucose transport, unspecified

    Showing 1–20 of 24

    DRG Codes

    3 rows

    DRG CodeDescription
    391Esophagitis, Gastroenteritis and Miscellaneous Digestive Disorders with MCC
    392Esophagitis, Gastroenteritis and Miscellaneous Digestive Disorders without MCC
    642Inborn and Other Disorders of Metabolism

    Typical Clinical Scenarios

    • An adult presents to the emergency department with new-onset, severe hypoglycemia unresponsive to oral glucose after several hours of fasting; laboratory testing shows abnormally low blood glucose with inappropriately elevated insulin and C-peptide levels, and imaging is pending to evaluate for an insulin-secreting tumor. A diagnosis from this group is assigned to capture a disorder of endogenous carbohydrate regulation causing hypoglycemia. Typical codes: E74.0, E74.00.
    • A pediatric patient with failure to thrive, recurrent vomiting, and developmental delay is evaluated by metabolic genetics; enzyme assays and genetic testing identify a congenital disorder of galactose metabolism leading to chronic feeding intolerance and growth problems. This chronic metabolic condition is coded from this group to document the inherited carbohydrate metabolism defect requiring long-term management and dietary modification. Typical codes: E74.2, E74.21.
    • A hospitalized adult with poorly controlled type 2 diabetes is found to have unexplained persistent lactic acidosis and features of a secondary carbohydrate metabolism disorder due to medication-induced mitochondrial dysfunction; the metabolic complication contributes to prolonged hospitalization and need for specialist consultation. A code from this group is used to indicate the secondary disorder of carbohydrate metabolism as a comorbidity affecting inpatient care. Typical codes: E74.89, E74.9.

    Related Codes

    E70-DISORDERS-OF-AROMATIC-AMINO-ACID-METABOLISM

    ICD-10-CM Code For Disorders Of Aromatic Amino-Acid Metabolism: Group Overview

    E71-DISORDERS-OF-BRANCHED-CHAIN-AMINO-ACID-METABOLISM

    ICD-10-CM Code For Disorders Of Branched Chain Amino Acid Metabolism And Fatty Acid Metabolism: Group Overview

    E72-OTHER-DISORDERS-OF-AMINO-ACID-METABOLISM

    ICD-10-CM Code For Other Disorders Of Amino-Acid Metabolism: Group Overview

    E73-LACTOSE-INTOLERANCE

    ICD-10-CM Code For Lactose Intolerance: Group Overview

    E75-DISORDERS-OF-SPHINGOLIPID-METABOLISM

    ICD-10-CM Code For Disorders Of Sphingolipid Metabolism And Other Lipid Storage Disorders: Group Overview

    E76-DISORDERS-OF-GLYCOSAMINOGLYCAN-METABOLISM

    ICD-10-CM Code For Disorders Of Glycosaminoglycan Metabolism: Group Overview

    E77-DISORDERS-OF-GLYCOPROTEIN-METABOLISM

    ICD-10-CM Code For Disorders Of Glycoprotein Metabolism: Group Overview

    E78-DISORDERS-OF-LIPOPROTEIN-METABOLISM

    ICD-10-CM Code For Disorders Of Lipoprotein Metabolism And Other Lipidemias: Group Overview

    E79-DISORDERS-OF-PURINE-AND-PYRIMIDINE-METABOLISM

    ICD-10-CM Code For Disorders Of Purine And Pyrimidine Metabolism: Group Overview

    E80-DISORDERS-OF-PORPHYRIN-AND-BILIRUBIN-METABOLISM

    ICD-10-CM Code For Disorders Of Porphyrin And Bilirubin Metabolism: Group Overview

    Showing 1–10 of 16

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
    Published by

    Trek Health powers OpenPayer with a leading commercial payer intelligence platform, seamlessly converting fragmented payer data into actionable insights for provider organizations.

    Trek Health ingests and normalizes Transparency in Coverage data and payer policy updates to give provider organizations a clear view of how commercial reimbursement behaves across markets, payers, and services. Our platform transforms raw payer disclosures into structured intelligence that supports contract evaluation, payer negotiations, and service line strategy. By combining market benchmarks with ongoing policy visibility, Trek helps teams identify variability, risk, and opportunity in commercial reimbursement. The result is faster insight, stronger negotiating positions, and more informed financial decisions.