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    v1.0.30
    OpenPayerBilling CodesMetabolic disordersICD-10-CM e84-cystic-fibrosis
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    ICD-10-CM Code For Cystic Fibrosis: Group Overview

    The International Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM) code group E84 includes diagnoses for cystic fibrosis and its common manifestations, such as chronic respiratory infections, bronchiectasis, and pancreatic insufficiency. These ICD-10-CM diagnosis codes are used to document clinical scenarios that capture disease severity, organ system involvement, and complications related to cystic fibrosis. Accurate coding within the ICD-10-CM E84 group supports proper claim adjudication and complete clinical documentation.

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    ICD-10-CM E84: Cystic Fibrosis Overview

    The ICD-10-CM E84 group represents cystic fibrosis diagnoses, a hereditary disorder primarily affecting the respiratory and digestive systems. These codes capture manifestations such as chronic pulmonary infections, bronchiectasis, and pancreatic insufficiency. Accurate coding is important for appropriate clinical documentation and reimbursement because it reflects disease severity and complications.

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    When to Use

    Use a code from this group when a patient has a confirmed diagnosis of cystic fibrosis or when documenting specific cystic fibrosis–related complications and organ system involvement. These codes are applied to reflect disease severity, presence of chronic infections, or treatment-related complications in claims and clinical records.

    ICD-10-CM Codes

    5 rows

    ICD-10-CM CodeDescription
    E84.0Cystic fibrosis with pulmonary manifestations
    E84.11Meconium ileus in cystic fibrosis
    E84.19Cystic fibrosis with other intestinal manifestations
    E84.8Cystic fibrosis with other manifestations
    E84.9Cystic fibrosis, unspecified

    DRG Codes

    10 rows

    DRG CodeDescription
    177Respiratory Infections and Inflammations with MCC
    178Respiratory Infections and Inflammations with CC
    179Respiratory Infections and Inflammations without CC/MCC
    393Other Digestive System Diagnoses with MCC
    394Other Digestive System Diagnoses with CC
    395Other Digestive System Diagnoses without CC/MCC
    640Miscellaneous Disorders of Nutrition, Metabolism, Fluids and Electrolytes with MCC
    641Miscellaneous Disorders of Nutrition, Metabolism, Fluids and Electrolytes without MCC
    791Prematurity with Major Problems
    793Full Term Neonate with Major Problems

    Typical Clinical Scenarios

    • A newborn with meconium ileus and failure to pass stool in the first 48 hours of life is evaluated in the neonatal unit; sweat chloride testing and genetic testing confirm cystic fibrosis as the underlying cause of intestinal obstruction, prompting initiation of pancreatic enzyme replacement and airway clearance planning. A diagnosis from this group is assigned to indicate cystic fibrosis as the primary genetic condition causing the neonatal presentation. Typical codes: E84.0
    • An adolescent with longstanding bronchiectasis, chronic productive cough, recurrent sinusitis, and malabsorption is seen in pulmonology for worsening respiratory symptoms and weight loss; care involves chronic respiratory therapies, monitoring for pulmonary exacerbations, and nutritional management. A code from this group is used to document the chronic multisystem genetic disorder driving pulmonary and gastrointestinal manifestations. Typical codes: E84.11, E84.19
    • An adult with known cystic fibrosis is hospitalized for an acute pulmonary exacerbation complicated by Pseudomonas aeruginosa infection and acute on chronic respiratory failure; the encounter documents the underlying cystic fibrosis as a comorbidity affecting treatment decisions and prognosis. A diagnosis from this group is recorded to identify the inherited disease complicating the acute illness. Typical codes: E84.8, E84.9

    Related Codes

    E70-DISORDERS-OF-AROMATIC-AMINO-ACID-METABOLISM

    ICD-10-CM Code For Disorders Of Aromatic Amino-Acid Metabolism: Group Overview

    E71-DISORDERS-OF-BRANCHED-CHAIN-AMINO-ACID-METABOLISM

    ICD-10-CM Code For Disorders Of Branched Chain Amino Acid Metabolism And Fatty Acid Metabolism: Group Overview

    E72-OTHER-DISORDERS-OF-AMINO-ACID-METABOLISM

    ICD-10-CM Code For Other Disorders Of Amino-Acid Metabolism: Group Overview

    E73-LACTOSE-INTOLERANCE

    ICD-10-CM Code For Lactose Intolerance: Group Overview

    E74-OTHER-DISORDERS-OF-CARBOHYDRATE-METABOLISM

    ICD-10-CM Code For Other Disorders Of Carbohydrate Metabolism: Group Overview

    E75-DISORDERS-OF-SPHINGOLIPID-METABOLISM

    ICD-10-CM Code For Disorders Of Sphingolipid Metabolism And Other Lipid Storage Disorders: Group Overview

    E76-DISORDERS-OF-GLYCOSAMINOGLYCAN-METABOLISM

    ICD-10-CM Code For Disorders Of Glycosaminoglycan Metabolism: Group Overview

    E77-DISORDERS-OF-GLYCOPROTEIN-METABOLISM

    ICD-10-CM Code For Disorders Of Glycoprotein Metabolism: Group Overview

    E78-DISORDERS-OF-LIPOPROTEIN-METABOLISM

    ICD-10-CM Code For Disorders Of Lipoprotein Metabolism And Other Lipidemias: Group Overview

    E79-DISORDERS-OF-PURINE-AND-PYRIMIDINE-METABOLISM

    ICD-10-CM Code For Disorders Of Purine And Pyrimidine Metabolism: Group Overview

    Showing 1–10 of 16

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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