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    v1.0.30
    OpenPayerBilling CodesOphthalmoscopy ProceduresCPT cpt-92242-dual-dye-fluorescein-indocyanine-angiography
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    CPT 92242: Dual-Dye Retinal Angiography with Interpretation

    Medicare pays $234 on average nationally for this procedure.

    CPT code 92242 describes retinal angiography in which a provider injects two different special dyes and captures multiple rapid-sequence photographic frames to highlight blood vessels, interprets the images, and prepares a report; service type: diagnostic ophthalmic imaging with angiographic interpretation; typical site of service: outpatient ophthalmology clinic or hospital outpatient imaging suite for evaluation of retinal and optic nerve vascular disorders, tumors, and preprocedure planning for certain laser treatments.

    For related coverage guidance, see recent payer policy updates: Navigated Transcranial Magnetic Stimulation for Preoperative Brain Mapping, Navigated Transcranial Magnetic Stimulation for Preoperative Brain Mapping, Navigated Transcranial Magnetic Stimulation for Preoperative Brain Mapping.

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    Table of contents

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    Clinical & Coding Specifications

    Clinical Context

    A 62-year-old patient with a history of diabetes and progressive visual disturbance is referred to a retinal specialist for evaluation of suspected diabetic retinopathy with possible macular edema. The patient presents to an outpatient ophthalmology clinic equipped with retinal imaging. After dilation and topical anesthesia as needed, the provider performs a dual-dye angiographic study, injecting fluorescein and indocyanine green intravenously while capturing timed rapid-sequence fundus photographs. The procedure documents retinal and choroidal vascular perfusion, identifies areas of leakage, neovascularization, or tumor vascularity, and guides treatment planning such as focal/grid laser or intravitreal injections. The interpreting physician reviews the image sequence, documents findings, provides diagnostic interpretation, and generates a signed report included in the medical record. Typical workflow steps include patient consent and allergy review, pupil dilation, IV access placement, sequential dye injections with imaging capture, post-procedure monitoring for adverse reactions, interpretation, and report generation. Typical sites of service are outpatient ophthalmology clinics, hospital outpatient departments, and ambulatory surgery centers when performed in conjunction with other procedures.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    92235Fluorescein angiography with interpretation and reportOften performed alone; 92242 expands to dual-dye studies when both fluorescein and indocyanine green are used
    92240Fluorescein angiography and angiographic imaging, less complexMay be performed in conjunction for single-dye studies or less extensive imaging
    92134Scanning computerized ophthalmic diagnostic imaging, posterior segment, with interpretation and report, unilateral or bilateralOptical coherence tomography (OCT) is commonly performed before or after angiography to assess macular edema and retinal thickness
    67028Intravitreal injection of a pharmacologic agentTherapeutic procedure that may follow angiographic diagnosis of neovascularization or macular edema
    67210Destruction of localized lesion of retina (e.g., photocoagulation)Laser photocoagulation treatments are often planned using angiographic findings

    Related Modifiers

    9 rows

    ModifierDescriptionWhen to Use
    26Modifier 26 (Professional Component) identifies and bills only the professional portion of a split service — the physician’s interpretation, report, and medical judgment — when the technical…- Use CPT Modifier -26 when you are billing only the professional component (PC) of a split‑bill eligible service—i.e., you performed the physician interpretation, medical judgment and prepared a…
    59Modifier 59 indicates a distinct procedural service when two procedures that are not normally billed together are clinically and procedurally separate. The CPT definition (as reiterated by CMS)…- Use modifier -59 to report a distinct procedural service when documentation supports that the procedure reported is not normally billed together with another service on the same day because of a…
    25CPT modifier 25 indicates that on the same day as another procedure or service, the same physician or other qualified health care professional provided a significant, separately identifiable…- When to apply: Use modifier 25 only on an E/M code to indicate the same provider delivered a significant, separately identifiable E/M service on the same day as another procedure or service — i.e.,…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    50Modifier –50 (Bilateral Procedure) is appended to a CPT code when an identical procedure is performed on paired anatomical structures during the same operative session. The AMA states to add…- Use modifier -50 when the same CPT surgical, diagnostic, or radiology procedure is performed on paired anatomical structures (both sides of the body) during the same operative/session by the same…
    76Modifier -76, Repeat Procedure or Service by Same Physician or Other Qualified Health Care Professional, is appended when the same provider performs an identical, medically necessary procedure or…- Use modifier -76 when the same physician or other qualified health care professional performs an identical procedure or service a second (or subsequent) time on the same date of service and the…
    78CPT modifier -78 indicates an unplanned, related return to the operating or procedure room by the same provider during the global postoperative period. It is appended when treatment for a…- Use modifier -78 when an unplanned, related complication during the original procedure’s global postoperative period requires the patient to return to a formal operating or procedure room and the…
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    207K00000X
    363L00000X
    207YS0123X
    225XM0800X
    207QP0002X
    207YX0901X
    222Z00000X
    224ZE0001X

    Related ICD-10-CM Codes

    8 rows

    ICD-10-CM CodeDescription
    D44.5Neoplasm of uncertain behavior of pineal gland
    H21.9Unspecified disorder of iris and ciliary body
    H35.52Pigmentary retinal dystrophy
    H35.70Unspecified separation of retinal layers
    H35.81Retinal edema
    H44.9Unspecified disorder of globe
    H52.4Presbyopia
    H54.7Unspecified visual loss

    Related Payer Policy Updates

    Specialty: Neurology/Neurosurgery1 / 2

    10 rows

    PolicyPayerEffective Date
    Navigated Transcranial Magnetic Stimulation for Preoperative Brain Mappingpremerabluecrossofwashington2027-02-05
    Navigated Transcranial Magnetic Stimulation for Preoperative Brain Mappingpremerabluecrossofwashington2027-02-05
    Navigated Transcranial Magnetic Stimulation for Preoperative Brain Mappingpremerabluecrossofwashington2027-02-05
    Calcitonin Gene-Related Peptide (CGRP) Inhibitors: Vyepti (eptinezumab-jjmr)Mass General Brigham Health Plan2027-01-04
    Clinical Review Criteria Intraoperative Neurophysiological Monitoring (IONM)Kaiser Permanente2027-01-01
    Open Neuroplasty Lumbar PlexusCigna2026-12-15
    Laser Interstitial Thermal TherapyCigna2026-11-15
    Remote Electrical Neuromodulation for Migraines (i.e., Nerivio®)bcbsvermont2026-11-01
    Artificial Cervical Intervertebral Discuniverahealthcare2026-10-15
    Lumbar Microdiscectomyuniverahealthcare2026-10-15

    Related Codes

    CPT-92201-EXTENDED-OPHTHALMOSCOPY-WITH-RETINAL-DRAWING

    CPT 92201: Extended Ophthalmoscopy with Retinal Drawing

    CPT-92202-EXTENDED-OPHTHALMOSCOPY-OPTIC-NERVE-MACULA-DRAWING

    CPT 92202: Extended Ophthalmoscopy with Optic Nerve or Macula Drawing

    CPT-92227-REMOTE-RETINAL-IMAGING-INTERPRETATION-REPORT

    CPT 92227: Remote Retinal Imaging with Remote Interpretation

    CPT-92228-REMOTE-RETINAL-IMAGING-INTERPRETATION-REPORTING

    CPT 92228: Remote Retinal Imaging Interpretation

    CPT-92229-POINT-OF-CARE-AUTONOMOUS-RETINAL-IMAGING

    CPT 92229: Autonomous Point-of-Care Retinal Imaging with Reporting

    CPT-92230-FLUORESCEIN-ANGIOGRAPHY-RETINAL-IMAGING-INTERPRETATION

    CPT 92230: Fluorescein Angiography with Interpretation and Report

    CPT-92235-FLUORESCEIN-ANGIOGRAPHY-MULTIFRAME-INTERPRETATION

    CPT 92235: Fluorescein Angiography, Multiframe/Serial Imaging

    CPT-92240-INDOCYANINE-GREEN-ANGIOGRAPHY-RETINAL-CHOROIDAL-VESSELS

    CPT 92240: Indocyanine Green Angiography of Retinal/Choroidal Vessels

    CPT-92250-FUNDUS-PHOTOGRAPHY-RETINAL-IMAGING

    CPT 92250: Fundus Photography of Posterior Segment

    CPT-92260-RETINAL-ARTERIAL-BLOOD-PRESSURE-MEASUREMENT

    CPT 92260: Retinal Arterial Blood Pressure Measurement

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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