Loading...

    Explore
    • Policy Monitoring
    • Live Policy Feed
    • Billing Codes
    • Healthcare Providers
    • Health Insurance Payers
    • States
    • Service Lines
    • Taxonomy Codes
    Lookup tools
    • Billing Code Lookup
    • CPT Modifier Lookup
    • Provider Taxonomy Code Lookup
    • Healthcare Provider & Facility Lookup
    • Health Insurance Payer Lookup
    • Payer Contact Directory

    Policy & Benchmark Tools

    • Prior Authorization Lookup
    • Coverage Criteria Lookup
    • Timely Filing Lookup
    • Billing Code Reimbursement Rates
    • Payer Comparison Dashboard
    • Facility Comparison Dashboard
    • All tools

    Company

    • About OpenPayer
    • Data Sources
    • Trek Health
    OpenPayerby Trek Health
    LinkedInYouTube

    © 2026 Trek Health. All rights reserved.

    OpenPayer is built and maintained by Trek Health.

    v1.0.30
    OpenPayerBilling CodesOphthalmoscopy ProceduresCPT cpt-92235-fluorescein-angiography-multiframe-interpretation
    Ask Trek AI about this page

    CPT 92235: Fluorescein Angiography, Multiframe/Serial Imaging

    Medicare pays $113 on average nationally for this procedure.

    CPT code 92235 is fluorescein angiography with multiframe or serial imaging through the pupil, where fluorescein dye highlights retinal and choroidal blood vessels; the performing physician interprets the images and prepares a report. Service type: diagnostic ocular angiography. Typical site of service: ophthalmology clinic or outpatient imaging suite for evaluation of retinal vascular disease, tumors, or preoperative planning for laser treatment.

    For related coverage guidance, see recent payer policy updates: Navigated Transcranial Magnetic Stimulation for Preoperative Brain Mapping, Navigated Transcranial Magnetic Stimulation for Preoperative Brain Mapping, Navigated Transcranial Magnetic Stimulation for Preoperative Brain Mapping.

    Customize your policy alerts

    Sign up for cpt 92235 policy alerts

    Get alerted when payer policies referencing 92235 are released or updated.

    Monitor payer policy activity

    Receive email alerts as soon as relevant payer policies are published or updated.

    Table of contents

    Progress1 / 6

    Explore openpayer tools

    • Billing CodesCPT, HCPCS, DRG & more
    • Reimbursement RatesCommercial vs. Medicare rate reports
    • Facility ComparisonBeds, revenue & payer mix
    • ProvidersHospitals & facilities
    • PayersPlans & market footprint
    • Taxonomy CodesNUCC specialty codes
    • ModifiersCPT modifiers & usage
    • Prior AuthorizationPA policies by payer & drug
    • Timely FilingFiling deadlines by payer
    • Coverage CriteriaMedical necessity by payer
    • Payer ContactsClaims, PA & appeals contacts
    View all tools

    Clinical & Coding Specifications

    Clinical Context

    A 62-year-old patient with a history of type 2 diabetes and progressively blurred central vision is referred to a retinal specialist for evaluation. The patient reports metamorphopsia and intermittent scotoma in the right eye. Visual acuity is reduced to 20/60 in the affected eye. The retinal specialist performs a fluorescein angiography study to visualize retinal and choroidal vasculature using intravenous fluorescein dye, acquires multiframe timed and serial images through the pupil of one eye, interprets the images, documents areas of microaneurysms, macular edema, and neovascularization, and prepares a formal report.

    Typical clinical workflow:

    • Referral and indications: Patient referred for diagnostic angiography for diabetic retinopathy, suspected macular edema, or retinal vascular occlusion.

    • Pre-procedure: Obtain informed consent, review allergies (especially to fluorescein), evaluate renal function if clinically indicated, explain possible sensations during dye injection (warmth, nausea), and verify any anticoagulation or pregnancy status.

    • Procedure: Intravenous administration of fluorescein dye, timed multiframe and serial photographic imaging of the retina through the pupil for one or both eyes, capture and store images, and monitor for immediate adverse reactions.

    • Post-procedure: Observe patient for a short period for adverse reactions, provide discharge instructions (possible yellow discoloration of skin/urine), and finalize the interpretive report with diagnostic impressions and recommended follow-up (e.g., anti-VEGF therapy, laser photocoagulation, or observation).

    Typical site of service: Outpatient ophthalmology clinic, hospital outpatient department, or ambulatory surgical center where retinal imaging equipment and emergency response capability are available.

    Service type: Diagnostic retinal angiography with interpretation and report using intravenous fluorescein.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    92235Fluorescein angiography with interpretation and reportPrimary code for diagnostic retinal angiography using fluorescein dye; includes interpretation and report.
    92250Fundus photography with interpretation and reportOften performed before or after angiography to document color fundus appearance and correlate with angiographic findings.
    92134Scanning computerized ophthalmic diagnostic imaging, posterior segment, with interpretation and report, unilateral or bilateralOptical coherence tomography (OCT) commonly performed alongside angiography to quantify macular edema and structural changes.
    67028Intravitreal injection of a pharmacologic agentTherapeutic procedure frequently performed after angiographic diagnosis of neovascularization or macular edema.

    Related Modifiers

    8 rows

    ModifierDescriptionWhen to Use
    26Modifier 26 (Professional Component) identifies and bills only the professional portion of a split service — the physician’s interpretation, report, and medical judgment — when the technical…- Use CPT Modifier -26 when you are billing only the professional component (PC) of a split‑bill eligible service—i.e., you performed the physician interpretation, medical judgment and prepared a…
    59Modifier 59 indicates a distinct procedural service when two procedures that are not normally billed together are clinically and procedurally separate. The CPT definition (as reiterated by CMS)…- Use modifier -59 to report a distinct procedural service when documentation supports that the procedure reported is not normally billed together with another service on the same day because of a…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    76Modifier -76, Repeat Procedure or Service by Same Physician or Other Qualified Health Care Professional, is appended when the same provider performs an identical, medically necessary procedure or…- Use modifier -76 when the same physician or other qualified health care professional performs an identical procedure or service a second (or subsequent) time on the same date of service and the…
    77Modifier 77 indicates that a previously performed procedure or service was legitimately repeated by a different physician or other qualified health care professional. The AMA’s CPT definition…- Use modifier 77 when a basic procedure or service already performed is repeated by a different physician or other qualified health care professional (for example, a second provider independently…
    50Modifier –50 (Bilateral Procedure) is appended to a CPT code when an identical procedure is performed on paired anatomical structures during the same operative session. The AMA states to add…- Use modifier -50 when the same CPT surgical, diagnostic, or radiology procedure is performed on paired anatomical structures (both sides of the body) during the same operative/session by the same…
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    207W00000X
    207K00000X
    103TP0814X
    163WN0800X
    363LN0000X
    385HR2050X
    207WX0108X
    2085R0001X

    Related Payer Policy Updates

    Specialty: Neurology/Neurosurgery1 / 2

    10 rows

    PolicyPayerEffective Date
    Navigated Transcranial Magnetic Stimulation for Preoperative Brain Mappingpremerabluecrossofwashington2027-02-05
    Navigated Transcranial Magnetic Stimulation for Preoperative Brain Mappingpremerabluecrossofwashington2027-02-05
    Navigated Transcranial Magnetic Stimulation for Preoperative Brain Mappingpremerabluecrossofwashington2027-02-05
    Calcitonin Gene-Related Peptide (CGRP) Inhibitors: Vyepti (eptinezumab-jjmr)Mass General Brigham Health Plan2027-01-04
    Clinical Review Criteria Intraoperative Neurophysiological Monitoring (IONM)Kaiser Permanente2027-01-01
    Open Neuroplasty Lumbar PlexusCigna2026-12-15
    Laser Interstitial Thermal TherapyCigna2026-11-15
    Remote Electrical Neuromodulation for Migraines (i.e., Nerivio®)bcbsvermont2026-11-01
    Artificial Cervical Intervertebral Discuniverahealthcare2026-10-15
    Lumbar Microdiscectomyuniverahealthcare2026-10-15

    Related Codes

    CPT-92201-EXTENDED-OPHTHALMOSCOPY-WITH-RETINAL-DRAWING

    CPT 92201: Extended Ophthalmoscopy with Retinal Drawing

    CPT-92202-EXTENDED-OPHTHALMOSCOPY-OPTIC-NERVE-MACULA-DRAWING

    CPT 92202: Extended Ophthalmoscopy with Optic Nerve or Macula Drawing

    CPT-92227-REMOTE-RETINAL-IMAGING-INTERPRETATION-REPORT

    CPT 92227: Remote Retinal Imaging with Remote Interpretation

    CPT-92228-REMOTE-RETINAL-IMAGING-INTERPRETATION-REPORTING

    CPT 92228: Remote Retinal Imaging Interpretation

    CPT-92229-POINT-OF-CARE-AUTONOMOUS-RETINAL-IMAGING

    CPT 92229: Autonomous Point-of-Care Retinal Imaging with Reporting

    CPT-92230-FLUORESCEIN-ANGIOGRAPHY-RETINAL-IMAGING-INTERPRETATION

    CPT 92230: Fluorescein Angiography with Interpretation and Report

    CPT-92240-INDOCYANINE-GREEN-ANGIOGRAPHY-RETINAL-CHOROIDAL-VESSELS

    CPT 92240: Indocyanine Green Angiography of Retinal/Choroidal Vessels

    CPT-92242-DUAL-DYE-FLUORESCEIN-INDOCYANINE-ANGIOGRAPHY

    CPT 92242: Dual-Dye Retinal Angiography with Interpretation

    CPT-92250-FUNDUS-PHOTOGRAPHY-RETINAL-IMAGING

    CPT 92250: Fundus Photography of Posterior Segment

    CPT-92260-RETINAL-ARTERIAL-BLOOD-PRESSURE-MEASUREMENT

    CPT 92260: Retinal Arterial Blood Pressure Measurement

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
    Published by

    Trek Health powers OpenPayer with a leading commercial payer intelligence platform, seamlessly converting fragmented payer data into actionable insights for provider organizations.

    Trek Health ingests and normalizes Transparency in Coverage data and payer policy updates to give provider organizations a clear view of how commercial reimbursement behaves across markets, payers, and services. Our platform transforms raw payer disclosures into structured intelligence that supports contract evaluation, payer negotiations, and service line strategy. By combining market benchmarks with ongoing policy visibility, Trek helps teams identify variability, risk, and opportunity in commercial reimbursement. The result is faster insight, stronger negotiating positions, and more informed financial decisions.

    67121
    Peripheral retinal cryotherapy
    Ancillary retinal treatment that may be planned based on angiographic localization of lesions.