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    v1.0.30
    OpenPayerBilling CodesChemistry ProceduresCPT cpt-82040-quantitative-albumin-measurement
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    CPT 82040: Quantitative Albumin Measurement

    Commercial payers pay $10 on average nationally for this procedure.

    CPT code 82040 describes a quantitative albumin measurement performed by a laboratory analyst on a serum, plasma, or whole blood specimen; this is a clinical laboratory service typically provided in an outpatient or hospital laboratory setting for evaluation of protein status and liver or renal function.

    For related coverage guidance, see recent payer policy updates: Diabetic Supplies, Radiofrequency Ablation for Thyroid Nodules, Continuous Glucose Monitoring and Insulin Delivery for Managing Diabetes (for Idaho Only).

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    National Reimbursement Benchmarks

    The national commercial average represented by BUCA sits at $10.4 for CPT 82040, framing the market midline while individual payer patterns vary. Blue Cross Blue Shield shows a relatively wide spread between its 25th and 75th percentiles ($7.40 to $16.90), a P75–P25 range of $9.50, and Aetna presents an even broader dispersion from $3.00 to $6.90 (range $3.90) but with extreme outliers up to $514.90. Cigna and UnitedHealth Group exhibit tighter interquartile spreads—Cigna’s P25–P75 runs $3.30 to $7.10 (range $3.80) and UnitedHealth Group’s $2.10 to $5.00 (range $2.90)—indicating more consistent negotiated commercial rates.

    Comparatively, Blue Cross Blue Shield and Aetna demonstrate the widest variability in the middle 50% of their commercial reimbursements, while UnitedHealth Group and Cigna are the tightest. BUCA’s mean of $10.4 functions as a practical market benchmark against which those payer dispersions can be viewed; payers with narrow interquartile ranges suggest greater pricing consistency, while wider ranges point to greater regional or contractual variability.

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    National Payer Mean Reimbursement Rates

    State Reimbursement Rates

    State: Alaska1 / 51

    Rate by payer

    Clinical & Coding Specifications

    Clinical Context

    A 62-year-old patient with a history of chronic liver disease and progressive peripheral edema presents to the outpatient clinic for routine monitoring. The primary care physician orders laboratory evaluation including a quantitative serum albumin measurement to assess nutritional status, hepatic synthetic function, and oncotic pressure. A phlebotomist collects a venous blood specimen (serum) and sends it to the clinical laboratory. In the laboratory, a medical technologist or lab analyst performs the quantitative assay for albumin using a colorimetric or automated chemistry analyzer. Results are reported in g/dL and routed to the ordering provider for interpretation alongside hepatic function tests and total protein. Typical workflow steps include specimen collection, accessioning, processing (centrifugation if serum/plasma), analysis using the albumin assay, verification by a qualified technologist or laboratory director, and electronic reporting to the clinician. This service is commonly performed as a stand-alone quantitative albumin test or as a component of a hepatic function panel for patients with suspected liver disease, malnutrition, nephrotic-range protein loss, or abnormal blood chemistry findings.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    80076Hepatic function panel (includes Albumin 82040, Bilirubin total 82247, Bilirubin direct , Alkaline phosphatase , Protein total , ALT , AST )

    Related Modifiers

    6 rows

    ModifierDescriptionWhen to Use
    26Modifier 26 (Professional Component) identifies and bills only the professional portion of a split service — the physician’s interpretation, report, and medical judgment — when the technical…- Use CPT Modifier -26 when you are billing only the professional component (PC) of a split‑bill eligible service—i.e., you performed the physician interpretation, medical judgment and prepared a…
    59Modifier 59 indicates a distinct procedural service when two procedures that are not normally billed together are clinically and procedurally separate. The CPT definition (as reiterated by CMS)…- Use modifier -59 to report a distinct procedural service when documentation supports that the procedure reported is not normally billed together with another service on the same day because of a…
    90Modifier ‑90 (Reference/Outside Laboratory) indicates that a laboratory test was performed by an entity other than the treating or reporting provider. The American Medical Association defines…- Use CPT modifier -90 when a laboratory test is performed by an outside/reference laboratory (an entity other than the treating or reporting physician or qualified professional) and the claim needs…
    91Modifier 91 — “Repeat Clinical Diagnostic Laboratory Test” — is appended when the exact same CPT laboratory test is performed more than once for the same patient on the same day because serial,…- Use modifier 91 when the exact same CPT laboratory test is performed more than once on the same patient on the same date because serial or repeated testing is medically necessary to monitor…
    92Modifier 92 (Alternative Laboratory Platform Testing) is used when laboratory tests are performed with single‑use, disposable, portable kits or transportable instruments. The AMA defines it for tests…- Use modifier 92 when a laboratory test is performed using a single‑use, disposable analytical device or kit (an alternative laboratory platform) that is portable and may be taken to or near the…
    99Modifier 99 is a placeholder modifier used when more modifiers apply to a single procedure than the claim form or electronic field allows. The AMA classifies it under Provider Services and Ambulatory…- Use CPT modifier -99 when more modifiers apply to a single procedure line than the claim form or payer field allows (CMS/Noridian: when more than four modifiers are needed); append modifier 99 on…

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    291U00000X
    207Q00000X
    207R00000X
    207U00000X
    122300000X
    364SP0807X
    3416S0300X
    251X00000X

    Related ICD-10-CM Codes

    30 rows

    ICD-10-CM CodeDescription
    D50.9Iron deficiency anemia, unspecified
    D64.9Anemia, unspecified
    E10.21Type 1 diabetes mellitus with diabetic nephropathy
    E10.9Type 1 diabetes mellitus without complications
    E11.22Type 2 diabetes mellitus with diabetic chronic kidney disease
    E11.9Type 2 diabetes mellitus without complications
    E40Kwashiorkor
    E41Nutritional marasmus
    E43Unspecified severe protein-calorie malnutrition
    E44.1Mild protein-calorie malnutrition

    Showing 1–10 of 30

    Related Payer Policy Updates

    Specialty: Endocrinology1 / 3

    10 rows

    PolicyPayerEffective Date
    Diabetic SuppliesCigna2026-10-15
    Radiofrequency Ablation for Thyroid NodulesCigna2026-10-15
    Continuous Glucose Monitoring and Insulin Delivery for Managing Diabetes (for Idaho Only)UnitedHealthcare2026-10-01
    Tzield (teplizumab-mzwv) CoverageUnitedHealthcare2026-10-01
    Continuous Glucose Monitoring and Insulin Delivery for Managing Diabetes (for Indiana Only)UnitedHealthcare2026-10-01
    Medical Necessity Guidelines Insulin PumpsMass General Brigham Health Plan2026-10-01
    Medical Necessity Guidelines: Continuous Glucose MonitorsMass General Brigham Health Plan2026-10-01
    Continuous Glucose MonitoringAmbetter Nevada2026-10-01
    Salivary Hormone TestingOscar Health2026-10-01
    Bone Turnover Markers TestingOscar Health2026-10-01

    Related Codes

    CPT-82009-KETONE-BODIES-QUALITATIVE-TEST

    CPT 82009: Qualitative Ketone Bodies Test

    CPT-82010-QUANTITATIVE-KETONE-BODIES-ASSAY-SERUM-PLASMA

    CPT 82010: Quantitative Ketone Bodies in Serum or Plasma

    CPT-82013-ACETYLCHOLINESTERASE-QUANTITATIVE-ASSAY

    CPT 82013: Quantitative Acetylcholinesterase (Acetylhydrolase) Assay

    CPT-82016-QUALITATIVE-ACYLCARNITINES-METABOLIC-SCREEN

    CPT 82016: Qualitative Acylcarnitines, Plasma/Serum/Urine

    CPT-82017-QUANTITATIVE-ACYLCARNITINE-ANALYSIS

    CPT 82017: Quantitative Acylcarnitine Analysis

    CPT-82024-QUANTITATIVE-CORTICOTROPIN-ACTH-ASSAY

    CPT 82024: Adrenocorticotropic Hormone (ACTH) Quantitative Assay

    CPT-82030-QUANTITATIVE-CAMP-PLASMA-URINE-ASSAY

    CPT 82030: Quantitative cyclic AMP assay on plasma or urine

    CPT-82042-QUANTITATIVE-ALBUMIN-NONBLOOD-FLUID

    CPT 82042: Albumin Quantitation in Non-Blood Body Fluid

    CPT-82043-URINE-ALBUMIN-QUANTITATION-KIDNEY-DISEASE

    CPT 82043: Urine Albumin Quantitative Assay

    CPT-82044-POINT-OF-CARE-URINE-MICROALBUMIN-SEMIQUANTITATIVE

    CPT 82044: Semiquantitative Urine Albumin (Microalbumin) Strip Test

    Showing 1–10 of 411

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    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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    Trek Health ingests and normalizes Transparency in Coverage data and payer policy updates to give provider organizations a clear view of how commercial reimbursement behaves across markets, payers, and services. Our platform transforms raw payer disclosures into structured intelligence that supports contract evaluation, payer negotiations, and service line strategy. By combining market benchmarks with ongoing policy visibility, Trek helps teams identify variability, risk, and opportunity in commercial reimbursement. The result is faster insight, stronger negotiating positions, and more informed financial decisions.

    82248
    84075
    84155
    84460
    84450
    A comprehensive panel that includes the albumin assay as a component; commonly ordered when evaluating liver function or abnormal liver enzymes.