ICD-10-CM Code For Other Anemias: Group Overview

The International Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM) code group D64 includes a range of anemias not classified elsewhere such as sideroblastic anemia, unspecified anemias, and other specified anemias that affect red blood cell production or survival. These ICD-10-CM diagnosis codes are used to document clinical scenarios including symptomatic anemia, anemia associated with systemic disease, and cases where specific etiologies are not identified, capturing severity and treatment complexity. Accurate coding within the ICD-10-CM D64 group supports proper claim adjudication, complete clinical documentation, and appropriate reimbursement.

Customize your policy alerts

Sign up for ICD-10-CM Code For Other Anemias: Group Overview policy alerts

Get alerted when relevant policies change without checking for updates manually.

Monitor payer policy activity

Receive email alerts as soon as relevant payer policies are published or updated.

ICD-10-CM D64: Other Anemias Overview

The ICD-10-CM D64 group includes various anemias not classified elsewhere, including sideroblastic anemias, hemolytic anemias of unspecified etiology, and other specified and unspecified anemias. These diagnoses target hematologic conditions that affect red blood cell production, morphology, or survival. Precise coding is important because it reflects disease severity and clinical complexity and supports appropriate reimbursement for hematology services.

When to Use

Use a code from this group when clinical documentation indicates an anemia that is specified as other or unspecified and does not belong to a different ICD-10-CM anemia category. Choose the most specific code available based on laboratory findings, clinical notes, and any documented underlying causes.

ICD-10-CM Codes

8 rows

ICD-10-CM Code	Description
D64.0	Hereditary sideroblastic anemia
D64.1	Secondary sideroblastic anemia due to disease
D64.2	Secondary sideroblastic anemia due to drugs and toxins
D64.3	Other sideroblastic anemias
D64.4	Congenital dyserythropoietic anemia
D64.81	Anemia due to antineoplastic chemotherapy
D64.89	Other specified anemias
D64.9	Anemia, unspecified

DRG Codes

2 rows

DRG Code	Description
811	Red Blood Cell Disorders with MCC
812	Red Blood Cell Disorders without MCC

Typical Clinical Scenarios

An elderly patient with chronic kidney disease stage 4 presents to primary care for routine follow-up reporting progressive fatigue and dyspnea on exertion. Laboratory testing shows normocytic, normochromic anemia with hemoglobin decreased from prior baseline and no evidence of iron deficiency or hemolysis; the clinician documents anemia related to chronic disease/renal impairment and manages it with adjustment of erythropoiesis-stimulating therapy and iron studies. A code from this group is assigned to capture a non-aplastic, non-hemolytic anemia as a comorbid chronic condition. Typical codes: D64.9, D64.81.
A young adult presents to the emergency department with acute onset pallor, severe fatigue, and petechial rash after starting a new anticonvulsant medication two weeks prior. Labs reveal pancytopenia with markedly reduced reticulocyte count and bone marrow biopsy demonstrates marked hypocellularity consistent with aplastic process; the immediate management includes transfusion support and hematology admission for immunosuppressive therapy. A code from this group is assigned to document the acute aplastic anemia as the primary hematologic diagnosis requiring urgent care. Typical codes: D64.0, D64.3.
A middle-aged patient with long-standing rheumatoid arthritis on chronic immunosuppressive therapy is hospitalized for sepsis and found to have microcytic anemia unresponsive to oral iron and evidence of myelodysplastic features on peripheral smear; hematology documents other specified anemia related to bone marrow dysfunction as a secondary diagnosis impacting transfusion needs and prognosis. A code from this group is used to indicate a non-specific or other specified anemia complicating the patient’s chronic disease and treatment. Typical codes: D64.89, D64.9.

Related Codes

D60-ACQUIRED-PURE-RED-CELL-APLASIA

ICD-10-CM Code For Acquired Pure Red Cell Aplasia Erythroblastopenia: Group Overview

D61-OTHER-APLASTIC-ANEMIAS

ICD-10-CM Code For Other Aplastic Anemias And Other Bone Marrow Failure Syndromes: Group Overview

D62-ACUTE-POSTHEMORRHAGIC-ANEMIA

ICD-10-CM Code For Acute Posthemorrhagic Anemia: Group Overview

D63-ANEMIA-IN-CHRONIC-DISEASES

ICD-10-CM Code For Anemia In Chronic Diseases Classified Elsewhere: Group Overview

Frequently Asked Questions

References

1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.

Published by

Trek Health powers OpenPayer with a leading commercial payer intelligence platform, seamlessly converting fragmented payer data into actionable insights for provider organizations.

Trek Health ingests and normalizes Transparency in Coverage data and payer policy updates to give provider organizations a clear view of how commercial reimbursement behaves across markets, payers, and services. Our platform transforms raw payer disclosures into structured intelligence that supports contract evaluation, payer negotiations, and service line strategy. By combining market benchmarks with ongoing policy visibility, Trek helps teams identify variability, risk, and opportunity in commercial reimbursement. The result is faster insight, stronger negotiating positions, and more informed financial decisions.

Explore openpayer tools

View all tools

When to Use

ICD-10-CM Codes

8 rows

ICD-10-CM Code	Description
D64.0	Hereditary sideroblastic anemia
D64.1	Secondary sideroblastic anemia due to disease
D64.2	Secondary sideroblastic anemia due to drugs and toxins
D64.3	Other sideroblastic anemias
D64.4	Congenital dyserythropoietic anemia
D64.81	Anemia due to antineoplastic chemotherapy
D64.89	Other specified anemias
D64.9	Anemia, unspecified

DRG Codes

2 rows

DRG Code	Description
811	Red Blood Cell Disorders with MCC
812	Red Blood Cell Disorders without MCC

Typical Clinical Scenarios

An elderly patient with chronic kidney disease stage 4 presents to primary care for routine follow-up reporting progressive fatigue and dyspnea on exertion. Laboratory testing shows normocytic, normochromic anemia with hemoglobin decreased from prior baseline and no evidence of iron deficiency or hemolysis; the clinician documents anemia related to chronic disease/renal impairment and manages it with adjustment of erythropoiesis-stimulating therapy and iron studies. A code from this group is assigned to capture a non-aplastic, non-hemolytic anemia as a comorbid chronic condition. Typical codes: D64.9, D64.81.
A young adult presents to the emergency department with acute onset pallor, severe fatigue, and petechial rash after starting a new anticonvulsant medication two weeks prior. Labs reveal pancytopenia with markedly reduced reticulocyte count and bone marrow biopsy demonstrates marked hypocellularity consistent with aplastic process; the immediate management includes transfusion support and hematology admission for immunosuppressive therapy. A code from this group is assigned to document the acute aplastic anemia as the primary hematologic diagnosis requiring urgent care. Typical codes: D64.0, D64.3.
A middle-aged patient with long-standing rheumatoid arthritis on chronic immunosuppressive therapy is hospitalized for sepsis and found to have microcytic anemia unresponsive to oral iron and evidence of myelodysplastic features on peripheral smear; hematology documents other specified anemia related to bone marrow dysfunction as a secondary diagnosis impacting transfusion needs and prognosis. A code from this group is used to indicate a non-specific or other specified anemia complicating the patient’s chronic disease and treatment. Typical codes: D64.89, D64.9.

Related Codes

D60-ACQUIRED-PURE-RED-CELL-APLASIA

ICD-10-CM Code For Acquired Pure Red Cell Aplasia Erythroblastopenia: Group Overview

D61-OTHER-APLASTIC-ANEMIAS

ICD-10-CM Code For Other Aplastic Anemias And Other Bone Marrow Failure Syndromes: Group Overview

D62-ACUTE-POSTHEMORRHAGIC-ANEMIA

ICD-10-CM Code For Acute Posthemorrhagic Anemia: Group Overview

D63-ANEMIA-IN-CHRONIC-DISEASES

ICD-10-CM Code For Anemia In Chronic Diseases Classified Elsewhere: Group Overview

Frequently Asked Questions

References

1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.

Published by

Trek Health powers OpenPayer with a leading commercial payer intelligence platform, seamlessly converting fragmented payer data into actionable insights for provider organizations.

ICD-10-CM Code For Other Anemias: Group Overview

Sign up for ICD-10-CM Code For Other Anemias: Group Overview policy alerts

ICD-10-CM D64: Other Anemias Overview

ICD-10-CM Code For Other Anemias: Group Overview

Sign up for ICD-10-CM Code For Other Anemias: Group Overview policy alerts

ICD-10-CM D64: Other Anemias Overview

When to Use

ICD-10-CM Codes

DRG Codes

Typical Clinical Scenarios

Related Codes

Which ICD-10-CM codes are included in the D64 group for other anemias?

How does accurate coding within `D64` affect reimbursement and claims?

What clinical scenarios are documented using `D64` codes?

Which related DRGs are associated with the D64 code group?

Are specific treatment recommendations provided for diagnoses in the `D64` group?

References

When to Use

ICD-10-CM Codes

DRG Codes

Typical Clinical Scenarios

Related Codes

Which ICD-10-CM codes are included in the D64 group for other anemias?

How does accurate coding within `D64` affect reimbursement and claims?

What clinical scenarios are documented using `D64` codes?

Which related DRGs are associated with the D64 code group?

Are specific treatment recommendations provided for diagnoses in the `D64` group?

References