Headline: CPT code 80344: Multi‑analyte antipsychotic panel for seven or more drugs

Lead: CPT code 80344 identifies a laboratory procedure for detecting or quantifying seven or more antipsychotic medications in a patient specimen. The code supports care coordination, medication safety, and forensic or compliance uses where broad antipsychotic screening is required.

CPT code 80344 represents comprehensive toxicology testing for antipsychotic medications when multiple agents must be assessed beyond single‑drug panels. Nationally, the code is relevant for inpatient and outpatient laboratories, behavioral health programs, and clinical toxicology services because it informs treatment decisions, monitors adherence or misuse, and supports medication reconciliation. Key payers addressed include Aetna, Blue Cross Blue Shield, Cigna Health, UnitedHealthcare, and Medicare.

Readers will learn the clinical context for ordering broad antipsychotic testing, the typical sites of service and service type, and which major payers commonly process claims for this testing. The publication also summarizes typical modifier usage (input provided), common operational settings for performing the test, and notes where input data were unavailable. Data not available in the input are identified as such rather than inferred.