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    v1.0.30
    OpenPayerBilling CodesOrgan or Disease Oriented PanelsCPT cpt-80061-lipid-panel-cholesterol-triglycerides
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    CPT 80061: Lipid Panel (Cholesterol and Triglycerides)

    Commercial payers pay $37 on average nationally for this procedure.

    CPT code 80061 represents a lipid panel laboratory test in which a lab analyst measures blood levels of cholesterol and triglycerides to assess lipid status; the service is a clinical laboratory test typically performed on a blood specimen collected in an outpatient laboratory, hospital lab, or physician office-based lab setting.

    For related coverage guidance, see recent payer policy updates: Long-Acting Injectable Antiretroviral Agents for HIV, B-Hemolytic Streptococcus Testing, Human Immunodeficiency Virus (HIV) — Coverage Criteria for Testing and Resistance Assays.

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    National Reimbursement Benchmarks

    National commercial reimbursement for CPT 80061 centers on BUCA’s average commercial rate of $36.90, with notable variation among major carriers. Blue Cross Blue Shield posts the highest dispersion and top-end rates (P75 $60.40, P25 $40.30), while Aetna and Cigna sit in the mid range of means ($22.10 and $16.00 respectively). UnitedHealth Group shows lower central tendency (median $8.00) and a relatively compressed middle distribution compared with Blue Cross Blue Shield.

    Measuring interquartile spread (P75 minus P25) highlights where rates cluster: Blue Cross Blue Shield’s spread is $20.10, BUCA’s spread is $17.50, Cigna’s spread is $11.80, Aetna’s spread is $16.40, and UnitedHealth Group’s spread is $7.40. UnitedHealth Group is the tightest payer by that measure, while Blue Cross Blue Shield is the widest, signaling the greatest variability in negotiated commercial payments.

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    National Payer Mean Reimbursement Rates

    State Reimbursement Rates

    State: Alaska1 / 51

    Rate by payer

    Clinical & Coding Specifications

    Clinical Context

    A 52-year-old adult presents to a primary care clinic for routine cardiovascular risk assessment. The patient has a history of obesity and a family history of premature coronary artery disease. The clinician orders a fasting lipid panel to measure total cholesterol, low-density lipoprotein (LDL) cholesterol, high-density lipoprotein (HDL) cholesterol, and triglycerides to assess dyslipidemia and guide risk-based management. A phlebotomy technician obtains a blood specimen and the sample is sent to the clinical medical laboratory for analysis under the billing code 80061. Results are reviewed by the ordering Family Medicine or Internal Medicine physician during a follow-up visit or via secure patient portal. Typical workflow includes specimen collection in an outpatient clinic, community laboratory, or hospital outpatient phlebotomy draw station, transport to the laboratory, analytic measurement by automated chemistry analyzers, result verification by the laboratory analyst, and incorporation into the patient’s medical record for clinician interpretation and treatment planning.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    83718Lipoprotein, direct measurement, HDL cholesterolPerformed when a direct HDL measurement is ordered or when added to the panel for specificity; complements 80061.

    Related Modifiers

    6 rows

    ModifierDescriptionWhen to Use
    26Modifier 26 (Professional Component) identifies and bills only the professional portion of a split service — the physician’s interpretation, report, and medical judgment — when the technical…- Use CPT Modifier -26 when you are billing only the professional component (PC) of a split‑bill eligible service—i.e., you performed the physician interpretation, medical judgment and prepared a…
    59Modifier 59 indicates a distinct procedural service when two procedures that are not normally billed together are clinically and procedurally separate. The CPT definition (as reiterated by CMS)…- Use modifier -59 to report a distinct procedural service when documentation supports that the procedure reported is not normally billed together with another service on the same day because of a…
    90Modifier ‑90 (Reference/Outside Laboratory) indicates that a laboratory test was performed by an entity other than the treating or reporting provider. The American Medical Association defines…- Use CPT modifier -90 when a laboratory test is performed by an outside/reference laboratory (an entity other than the treating or reporting physician or qualified professional) and the claim needs…
    91Modifier 91 — “Repeat Clinical Diagnostic Laboratory Test” — is appended when the exact same CPT laboratory test is performed more than once for the same patient on the same day because serial,…- Use modifier 91 when the exact same CPT laboratory test is performed more than once on the same patient on the same date because serial or repeated testing is medically necessary to monitor…
    92Modifier 92 (Alternative Laboratory Platform Testing) is used when laboratory tests are performed with single‑use, disposable, portable kits or transportable instruments. The AMA defines it for tests…- Use modifier 92 when a laboratory test is performed using a single‑use, disposable analytical device or kit (an alternative laboratory platform) that is portable and may be taken to or near the…
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    291U00000X
    207Q00000X
    207R00000X
    207RH0003X
    1835N1003X
    313M00000X
    374700000X
    282N00000X

    Related ICD-10-CM Codes

    5 rows

    ICD-10-CM CodeDescription
    E78.0
    E78.1Pure hyperglyceridemia
    E78.2Mixed hyperlipidemia
    E78.5Hyperlipidemia, unspecified
    Z13.220Encounter for screening for lipoid disorders

    Related Payer Policy Updates

    Specialty: Infectious Disease1 / 3

    10 rows

    PolicyPayerEffective Date
    Long-Acting Injectable Antiretroviral Agents for HIVColorado Rocky Mountain Health Plans2026-10-01
    B-Hemolytic Streptococcus TestingOscar Health2026-10-01
    Human Immunodeficiency Virus (HIV) — Coverage Criteria for Testing and Resistance AssaysOscar Health2026-10-01
    Hepatitis Testing (A, B, C, D) Coverage CriteriaOscar Health2026-10-01
    Lyme Disease Testing Coverage CriteriaOscar Health2026-10-01
    Pathogen Panel TestingOscar Health2026-10-01
    Diagnostic Testing of Common Sexually Transmitted InfectionsOscar Health2026-10-01
    Coronavirus Testing in the Outpatient SettingOscar Health2026-10-01
    Testing for Vector-Borne InfectionsOscar Health2026-10-01
    Testing for Diagnosis of Active or Latent TuberculosisOscar Health2026-10-01

    Related Codes

    CPT-80047-BASIC-METABOLIC-PANEL-BMP

    CPT 80047: Basic Metabolic Panel (BMP)

    CPT-80048-BASIC-METABOLIC-PANEL-BMP

    CPT 80048: Basic Metabolic Panel (BMP)

    CPT-80050-GENERAL-HEALTH-PANEL-SCREENING-LAB

    CPT 80050: General Health Panel Screening

    CPT-80051-ELECTROLYTE-PANEL-NA-CL-K-CLO-CO2

    CPT 80051: Electrolyte Panel (Na, K, Cl, CO2)

    CPT-80053-COMPREHENSIVE-METABOLIC-PANEL-CMP

    CPT 80053: Comprehensive Metabolic Panel (CMP)

    CPT-80055-OBSTETRIC-PANEL-PRENATAL-LAB-TESTING

    CPT 80055: Obstetric Laboratory Panel

    CPT-80069-RENAL-FUNCTION-PANEL-LAB-TEST

    CPT 80069: Renal Function Panel, Blood

    CPT-80074-ACUTE-HEPATITIS-PANEL-SEROLOGY

    CPT 80074: Acute Hepatitis Serology Panel

    CPT-80076-HEPATIC-FUNCTION-PANEL-LIVER-CHEMISTRY

    CPT 80076: Hepatic Function Panel (Liver Chemistry Tests)

    CPT-80081-OBSTETRIC-PANEL-INITIAL-PRENATAL-TESTING

    CPT 80081: Obstetric Screening Panel for Prenatal Care

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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    Trek Health powers OpenPayer with a leading commercial payer intelligence platform, seamlessly converting fragmented payer data into actionable insights for provider organizations.

    Trek Health ingests and normalizes Transparency in Coverage data and payer policy updates to give provider organizations a clear view of how commercial reimbursement behaves across markets, payers, and services. Our platform transforms raw payer disclosures into structured intelligence that supports contract evaluation, payer negotiations, and service line strategy. By combining market benchmarks with ongoing policy visibility, Trek helps teams identify variability, risk, and opportunity in commercial reimbursement. The result is faster insight, stronger negotiating positions, and more informed financial decisions.

    84478TriglyceridesIndividual triglyceride measurement; component of the lipid panel and may be billed separately if ordered alone.
    80053Comprehensive metabolic panelOften ordered alongside 80061 to evaluate metabolic contributors to dyslipidemia (liver function, glucose, electrolytes).
    83036Hemoglobin A1cFrequently ordered with lipid testing to assess glycemic control and cardiometabolic risk in patients with or at risk for diabetes.