CPT 80050: General Health Panel Screening

Commercial payers pay $62 on average nationally for this procedure.

CPT code 80050 describes a general health panel laboratory service where a lab analyst performs a defined group of clinical chemistry and related tests ordered specifically as a screening general health panel; service type is clinical laboratory testing (screening panel) and the typical site of service is a clinical laboratory or outpatient phlebotomy/ambulatory setting.

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National Reimbursement Benchmarks

BUCA (average commercial) centers the commercial market for CPT 80050 at $62.50 mean with an interquartile spread from $41.90 to $78.20, indicating moderate dispersion around that commercial average. Blue Cross Blue Shield’s interquartile span is $97.80 - $55.80 = $42.00, one of the wider IQRs here, while Aetna’s IQR is $60.90 - $28.60 = $32.30 and Cigna’s is $52.90 - $21.60 = $31.30. UnitedHealth Group is the tightest among provided payers with an IQR of $42.40 - $19.90 = $22.50, reflecting relatively concentrated commercial contracting for this code.

List-level comparisons show Blue Cross Blue Shield sits toward the higher end of central tendency ($76.80 mean) while UnitedHealth Group and Cigna present lower means ($36.30 and $40.70 respectively); Aetna’s mean of $52.80 falls between those groups. The P90 values where available further highlight tails: Aetna reaches $111.80 and Blue Cross Blue Shield $114.40, suggesting notable high-end reimbursement outcomes for those carriers compared with others.

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CPT 80050: General Health Panel Screening

Commercial payers pay $62 on average nationally for this procedure.

Customize your policy alerts

Sign up for cpt 80050 policy alerts

Get alerted when payer policies referencing 80050 are released or updated.

Monitor payer policy activity

Receive email alerts as soon as relevant payer policies are published or updated.

National Reimbursement Benchmarks

National Payer Mean Reimbursement Rates

Clinical & Coding Specifications

Clinical Context

A 52-year-old patient presents to a primary care clinic for an annual preventive visit and requests routine laboratory screening. The clinician orders a general health panel to evaluate baseline metabolic and hematologic status as part of screening rather than to investigate a specific symptom. The patient has no acute complaints; vital signs are stable. A phlebotomy technician draws blood in the clinic's ambulatory laboratory; specimens are sent to the clinical laboratory where the lab analyst performs the bundled tests included in the general health panel under 80050. Results are routed to the ordering clinician for review and documented in the electronic medical record. Typical workflow steps: order placement as a screening panel, patient registration and consent, venipuncture, specimen processing and testing in the laboratory, result verification by the laboratory analyst, electronic reporting to the clinician, and incorporation into the preventive visit note.

Related CPT Codes

CPT Code	Description	Relationship to This Procedure
`36415`	Collection of venous blood by venipuncture	Performed immediately prior to `80050` to obtain the specimen for the general health panel.
`80500`	Basic metabolic panel (example single-test code)	Individual component tests that may be ordered separately; when ordered diagnostically, individual test codes are used instead of the bundled `80050` panel.
`85025`	Complete CBC with automated differential	Often ordered alongside or as a component of a general health panel; may be billed separately if ordered diagnostically rather than as part of the screening panel.
`99000`	Handling and/or conveyance of specimen	Administrative or courier services associated with transporting specimens to the performing laboratory; used where applicable.
`G0008`	Administration of influenza virus vaccine (separate example of preventive service)	Preventive visit services commonly delivered the same day as screening labs; listed as an example of co-occurring preventive procedures.

Related Modifiers

8 rows

Modifier	Description	When to Use
25	CPT modifier 25 indicates that on the same day as another procedure or service, the same physician or other qualified health care professional provided a significant, separately identifiable…	- When to apply: Use modifier 25 only on an E/M code to indicate the same provider delivered a significant, separately identifiable E/M service on the same day as another procedure or service — i.e.,…
26	Modifier 26 (Professional Component) identifies and bills only the professional portion of a split service — the physician’s interpretation, report, and medical judgment — when the technical…	- Use CPT Modifier -26 when you are billing only the professional component (PC) of a split‑bill eligible service—i.e., you performed the physician interpretation, medical judgment and prepared a…
52	Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…	- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
53	Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…	- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
59	Modifier 59 indicates a distinct procedural service when two procedures that are not normally billed together are clinically and procedurally separate. The CPT definition (as reiterated by CMS)…	- Use modifier -59 to report a distinct procedural service when documentation supports that the procedure reported is not normally billed together with another service on the same day because of a…
90	Modifier ‑90 (Reference/Outside Laboratory) indicates that a laboratory test was performed by an entity other than the treating or reporting provider. The American Medical Association defines…	- Use CPT modifier -90 when a laboratory test is performed by an outside/reference laboratory (an entity other than the treating or reporting physician or qualified professional) and the claim needs…
91	Modifier 91 — “Repeat Clinical Diagnostic Laboratory Test” — is appended when the exact same CPT laboratory test is performed more than once for the same patient on the same day because serial,…	- Use modifier 91 when the exact same CPT laboratory test is performed more than once on the same patient on the same date because serial or repeated testing is medically necessary to monitor…
95	Modifier 95 indicates that a service was provided via synchronous, real‑time audio‑video telehealth rather than in‑person. Per CMS, AAPC and professional associations, append modifier 95 to claim…	- Use modifier 95 to indicate a service was furnished via synchronous, real‑time audiovisual telehealth (a live audio‑video conference between patient and provider) rather than in‑person. - Pair…

Related Provider Taxonomies

8 rows

Taxonomy Code	Specialty	Notes
207Q00000X	Family Medicine Physician	Family Medicine is the medical specialty which is concerned with the total health care of the individual and the family. It is the specialty in breadt…
207R00000X	Internal Medicine Physician	A physician who provides long-term, comprehensive care in the office and the hospital, managing both common and complex illness of adolescents, adults…
207L00000X	Anesthesiology Physician	An anesthesiologist is trained to provide pain relief and maintenance, or restoration, of a stable condition during and immediately following an opera…
261QR0405X	Substance Use Disorder Rehabilitation Clinic/Center	Ambulatory Health Care Facilities · Clinic/Center
163WC1600X	Continuing Education/Staff Development Registered Nurse	Nursing Service Providers · Registered Nurse
261QD0000X	Dental Clinic/Center	Ambulatory Health Care Facilities · Clinic/Center
146L00000X	Paramedic	An EMT, Paramedic is an individual trained and certified to perform advanced life support (ALS) in medical emergencies based on individual state board…
246XC2903X	Vascular Specialist/Technologist Cardiovascular	A vascular technologist, also known as a vascular sonographer, creates images of blood vessels and collects data that help physicians diagnose disorde…

Related Codes

CPT-80047-BASIC-METABOLIC-PANEL-BMP

CPT 80047: Basic Metabolic Panel (BMP)

CPT-80048-BASIC-METABOLIC-PANEL-BMP

CPT 80048: Basic Metabolic Panel (BMP)

CPT-80051-ELECTROLYTE-PANEL-NA-CL-K-CLO-CO2

CPT 80051: Electrolyte Panel (Na, K, Cl, CO2)

CPT-80053-COMPREHENSIVE-METABOLIC-PANEL-CMP

CPT 80053: Comprehensive Metabolic Panel (CMP)

CPT-80055-OBSTETRIC-PANEL-PRENATAL-LAB-TESTING

CPT 80055: Obstetric Laboratory Panel

CPT-80061-LIPID-PANEL-CHOLESTEROL-TRIGLYCERIDES

CPT 80061: Lipid Panel (Cholesterol and Triglycerides)

CPT-80069-RENAL-FUNCTION-PANEL-LAB-TEST

CPT 80069: Renal Function Panel, Blood

CPT-80074-ACUTE-HEPATITIS-PANEL-SEROLOGY

CPT 80074: Acute Hepatitis Serology Panel

CPT-80076-HEPATIC-FUNCTION-PANEL-LIVER-CHEMISTRY

CPT 80076: Hepatic Function Panel (Liver Chemistry Tests)

CPT-80081-OBSTETRIC-PANEL-INITIAL-PRENATAL-TESTING

CPT 80081: Obstetric Screening Panel for Prenatal Care

Frequently Asked Questions

References

1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.

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Trek Health ingests and normalizes Transparency in Coverage data and payer policy updates to give provider organizations a clear view of how commercial reimbursement behaves across markets, payers, and services. Our platform transforms raw payer disclosures into structured intelligence that supports contract evaluation, payer negotiations, and service line strategy. By combining market benchmarks with ongoing policy visibility, Trek helps teams identify variability, risk, and opportunity in commercial reimbursement. The result is faster insight, stronger negotiating positions, and more informed financial decisions.

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Clinical & Coding Specifications

Clinical Context

Related CPT Codes

CPT Code	Description	Relationship to This Procedure
`36415`	Collection of venous blood by venipuncture	Performed immediately prior to `80050` to obtain the specimen for the general health panel.
`80500`	Basic metabolic panel (example single-test code)	Individual component tests that may be ordered separately; when ordered diagnostically, individual test codes are used instead of the bundled `80050` panel.
`85025`	Complete CBC with automated differential	Often ordered alongside or as a component of a general health panel; may be billed separately if ordered diagnostically rather than as part of the screening panel.
`99000`	Handling and/or conveyance of specimen	Administrative or courier services associated with transporting specimens to the performing laboratory; used where applicable.
`G0008`	Administration of influenza virus vaccine (separate example of preventive service)	Preventive visit services commonly delivered the same day as screening labs; listed as an example of co-occurring preventive procedures.

Related Modifiers

8 rows

Modifier	Description	When to Use
25	CPT modifier 25 indicates that on the same day as another procedure or service, the same physician or other qualified health care professional provided a significant, separately identifiable…	- When to apply: Use modifier 25 only on an E/M code to indicate the same provider delivered a significant, separately identifiable E/M service on the same day as another procedure or service — i.e.,…
26	Modifier 26 (Professional Component) identifies and bills only the professional portion of a split service — the physician’s interpretation, report, and medical judgment — when the technical…	- Use CPT Modifier -26 when you are billing only the professional component (PC) of a split‑bill eligible service—i.e., you performed the physician interpretation, medical judgment and prepared a…
52	Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…	- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
53	Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…	- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
59	Modifier 59 indicates a distinct procedural service when two procedures that are not normally billed together are clinically and procedurally separate. The CPT definition (as reiterated by CMS)…	- Use modifier -59 to report a distinct procedural service when documentation supports that the procedure reported is not normally billed together with another service on the same day because of a…
90	Modifier ‑90 (Reference/Outside Laboratory) indicates that a laboratory test was performed by an entity other than the treating or reporting provider. The American Medical Association defines…	- Use CPT modifier -90 when a laboratory test is performed by an outside/reference laboratory (an entity other than the treating or reporting physician or qualified professional) and the claim needs…
91	Modifier 91 — “Repeat Clinical Diagnostic Laboratory Test” — is appended when the exact same CPT laboratory test is performed more than once for the same patient on the same day because serial,…	- Use modifier 91 when the exact same CPT laboratory test is performed more than once on the same patient on the same date because serial or repeated testing is medically necessary to monitor…
95	Modifier 95 indicates that a service was provided via synchronous, real‑time audio‑video telehealth rather than in‑person. Per CMS, AAPC and professional associations, append modifier 95 to claim…	- Use modifier 95 to indicate a service was furnished via synchronous, real‑time audiovisual telehealth (a live audio‑video conference between patient and provider) rather than in‑person. - Pair…

Related Provider Taxonomies

8 rows

Taxonomy Code	Specialty	Notes
207Q00000X	Family Medicine Physician	Family Medicine is the medical specialty which is concerned with the total health care of the individual and the family. It is the specialty in breadt…
207R00000X	Internal Medicine Physician	A physician who provides long-term, comprehensive care in the office and the hospital, managing both common and complex illness of adolescents, adults…
207L00000X	Anesthesiology Physician	An anesthesiologist is trained to provide pain relief and maintenance, or restoration, of a stable condition during and immediately following an opera…
261QR0405X	Substance Use Disorder Rehabilitation Clinic/Center	Ambulatory Health Care Facilities · Clinic/Center
163WC1600X	Continuing Education/Staff Development Registered Nurse	Nursing Service Providers · Registered Nurse
261QD0000X	Dental Clinic/Center	Ambulatory Health Care Facilities · Clinic/Center
146L00000X	Paramedic	An EMT, Paramedic is an individual trained and certified to perform advanced life support (ALS) in medical emergencies based on individual state board…
246XC2903X	Vascular Specialist/Technologist Cardiovascular	A vascular technologist, also known as a vascular sonographer, creates images of blood vessels and collects data that help physicians diagnose disorde…

Related Codes

CPT-80047-BASIC-METABOLIC-PANEL-BMP

CPT 80047: Basic Metabolic Panel (BMP)

CPT-80048-BASIC-METABOLIC-PANEL-BMP

CPT 80048: Basic Metabolic Panel (BMP)

CPT-80051-ELECTROLYTE-PANEL-NA-CL-K-CLO-CO2

CPT 80051: Electrolyte Panel (Na, K, Cl, CO2)

CPT-80053-COMPREHENSIVE-METABOLIC-PANEL-CMP

CPT 80053: Comprehensive Metabolic Panel (CMP)

CPT-80055-OBSTETRIC-PANEL-PRENATAL-LAB-TESTING

CPT 80055: Obstetric Laboratory Panel

CPT-80061-LIPID-PANEL-CHOLESTEROL-TRIGLYCERIDES

CPT 80061: Lipid Panel (Cholesterol and Triglycerides)

CPT-80069-RENAL-FUNCTION-PANEL-LAB-TEST

CPT 80069: Renal Function Panel, Blood

CPT-80074-ACUTE-HEPATITIS-PANEL-SEROLOGY

CPT 80074: Acute Hepatitis Serology Panel

CPT-80076-HEPATIC-FUNCTION-PANEL-LIVER-CHEMISTRY

CPT 80076: Hepatic Function Panel (Liver Chemistry Tests)

CPT-80081-OBSTETRIC-PANEL-INITIAL-PRENATAL-TESTING

CPT 80081: Obstetric Screening Panel for Prenatal Care

Frequently Asked Questions

References

1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.

Published by

Trek Health powers OpenPayer with a leading commercial payer intelligence platform, seamlessly converting fragmented payer data into actionable insights for provider organizations.

CPT 80050: General Health Panel Screening

Sign up for cpt 80050 policy alerts

National Reimbursement Benchmarks

CPT 80050: General Health Panel Screening

Sign up for cpt 80050 policy alerts

National Reimbursement Benchmarks

Clinical & Coding Specifications

Clinical Context

Related CPT Codes

Related Modifiers

Related Provider Taxonomies

Related Codes

What does CPT 80050 describe?

When is it appropriate to use the 80050 panel code instead of individual test codes?

Can venipuncture be billed separately when 80050 is performed?

Which diagnosis codes commonly accompany an order for CPT 80050?

Where does the clinical workflow for 80050 typically occur and what steps are involved?

References

Clinical & Coding Specifications

Clinical Context

Related CPT Codes

Related Modifiers

Related Provider Taxonomies

Related Codes

What does CPT 80050 describe?

When is it appropriate to use the 80050 panel code instead of individual test codes?

Can venipuncture be billed separately when 80050 is performed?

Which diagnosis codes commonly accompany an order for CPT 80050?

Where does the clinical workflow for 80050 typically occur and what steps are involved?

References