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    OpenPayerBilling CodesIntroduction Procedures on the PenisCPT cpt-54250-nocturnal-penile-tumescence-npt-monitoring
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    CPT 54250: Nocturnal Penile Tumescence (NPT) Testing

    Medicare pays $84 on average nationally for this procedure.

    CPT code 54250 describes nocturnal penile tumescence (NPT) testing, an overnight electronic monitoring procedure that records frequency, rigidity, and circumferential changes of erections during REM sleep to evaluate the extent of erectile dysfunction; service type: diagnostic sleep-associated urologic testing, typical site of service: sleep lab or outpatient urology clinic with overnight monitoring capabilities.

    For related coverage guidance, see recent payer policy updates: Lymphedema - Surgical Treatment - Medical Policy, Breast Reduction (Mammoplasty) Surgery, Mastectomy Treatment, Breast Reconstruction and Mastectomy Hospital Stays Mandates.

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    Clinical & Coding Specifications

    Clinical Context

    A 48-year-old male presents to a urology clinic with a 6-month history of erectile dysfunction (ED) characterized by difficulty achieving and maintaining erections sufficient for sexual intercourse. The patient reports nocturnal and morning erections have decreased. The urologist orders nocturnal penile tumescence testing to distinguish organic from psychogenic causes. The procedure is scheduled as an overnight home-based or sleep-laboratory monitored test. A trained technician instructs the patient on device placement (rigidity rings, sensors) prior to sleep; the device electronically records frequency, duration, rigidity, and circumferential changes during REM cycles. The recording is retrieved the next day, interpreted by the urologist, and documented in the clinic note. Results help determine whether the ED is primarily physiologic (reduced nocturnal erections) or psychogenic (normal nocturnal erections), guiding further evaluation and management.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    54250Nocturnal penile tumescence (NPT), electronically monitoring frequency, rigidity, and/or circumferential changes of erections during REM sleepPrimary code for the overnight diagnostic monitoring procedure.
    90911Biofeedback training, any modality, per 15 minutes; therapist timeMay be used in pelvic floor rehabilitation programs for sexual dysfunction adjunctive to diagnostic evaluation.
    95810Polysomnography; sleep staging with continuous airway pressure titration, attended by technologistSleep laboratory-based NPT may be performed in conjunction with broader polysomnography when sleep disorder comorbidity is suspected.
    99000Handling and/or conveyance of specimen for transfer from physician to laboratoryNot typically used; Data not available in the input.
    99070Supplies and materials (e.g., bandages, gauze, instruments) provided by the physician over and above those usually included with the office visit or procedureUse for disposable sensors or recording supplies when billable separately.

    Related Modifiers

    9 rows

    ModifierDescriptionWhen to Use
    26Modifier 26 (Professional Component) identifies and bills only the professional portion of a split service — the physician’s interpretation, report, and medical judgment — when the technical…- Use CPT Modifier -26 when you are billing only the professional component (PC) of a split‑bill eligible service—i.e., you performed the physician interpretation, medical judgment and prepared a…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    59Modifier 59 indicates a distinct procedural service when two procedures that are not normally billed together are clinically and procedurally separate. The CPT definition (as reiterated by CMS)…- Use modifier -59 to report a distinct procedural service when documentation supports that the procedure reported is not normally billed together with another service on the same day because of a…
    76Modifier -76, Repeat Procedure or Service by Same Physician or Other Qualified Health Care Professional, is appended when the same provider performs an identical, medically necessary procedure or…- Use modifier -76 when the same physician or other qualified health care professional performs an identical procedure or service a second (or subsequent) time on the same date of service and the…
    77Modifier 77 indicates that a previously performed procedure or service was legitimately repeated by a different physician or other qualified health care professional. The AMA’s CPT definition…- Use modifier 77 when a basic procedure or service already performed is repeated by a different physician or other qualified health care professional (for example, a second provider independently…
    78CPT modifier -78 indicates an unplanned, related return to the operating or procedure room by the same provider during the global postoperative period. It is appended when treatment for a…- Use modifier -78 when an unplanned, related complication during the original procedure’s global postoperative period requires the patient to return to a formal operating or procedure room and the…
    79Modifier 79 indicates a surgical procedure performed during the postoperative global period of a prior surgery that is unrelated to the original procedure. Per AMA/CPT and CMS guidance, it is…- Use modifier 79 when the same physician (or same‑specialty physician in the same group) performs a surgical procedure during the postoperative global period of a prior surgery and the new procedure…
    91Modifier 91 — “Repeat Clinical Diagnostic Laboratory Test” — is appended when the exact same CPT laboratory test is performed more than once for the same patient on the same day because serial,…- Use modifier 91 when the exact same CPT laboratory test is performed more than once on the same patient on the same date because serial or repeated testing is medically necessary to monitor…

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    2084P0800X
    363L00000X
    207UN0901X
    364SP0811X
    225400000X
    251V00000X
    332B00000X
    207RH0003X

    Related ICD-10-CM Codes

    24 rows

    ICD-10-CM CodeDescription
    E03.9Hypothyroidism, unspecified
    E11.65Type 2 diabetes mellitus with hyperglycemia
    E29.1Testicular hypofunction
    E29.8Other testicular dysfunction
    E29.9Testicular dysfunction, unspecified
    E78.5Hyperlipidemia, unspecified
    F10.20Alcohol dependence, uncomplicated
    F11.20Opioid dependence, uncomplicated
    F52.21Male erectile disorder
    F52.22Female sexual arousal disorder

    Showing 1–10 of 24

    Related Payer Policy Updates

    Specialty: Plastic/Reconstructive Surgery1 / 2

    10 rows

    PolicyPayerEffective Date
    Lymphedema - Surgical Treatment - Medical PolicyHealth-New-England2027-02-01
    Breast Reduction (Mammoplasty) SurgeryKaiser Permanente2027-02-01
    Mastectomy Treatment, Breast Reconstruction and Mastectomy Hospital Stays MandatesBlue Cross Blue Shield - Rhode Island2027-01-01
    Lipodystrophy Syndrome - HIV Associated - Medical PolicyHealth-New-England2026-12-01
    Abdominal Panniculectomy and Excision of Excessive Skin and Subcutaneous Tissue - Medical PolicyHealth-New-England2026-12-01
    Reduction MammaplastyBlue Cross Blue Shield - North Dakota2026-11-01
    Cosmetic and Reconstructive ProceduresAmbetter Georgia2026-11-01
    Surgical Treatment of Lipedema and Lymphedemahusky_health2026-11-01
    Rhinoplasty Medical Necessity and Site of ServicePremera Bluecross2026-10-14
    Reconstructive Breast Surgery/Mastopexy, and Management of Breast ImplantsBlue Cross Blue Shield - North Dakota2026-10-01

    Related Codes

    CPT-54200-PENILE-INJECTION-FOR-PEYRONIE-DISEASE

    CPT 54200: Intralesional Injection for Peyronie Disease

    CPT-54205-PENILE-PLAQUE-EXPOSURE-AND-INJECTION-FOR-PEYRONIE-DISEASE

    CPT 54205: Penile Plaque Exposure and Injection for Peyronie Disease

    CPT-54220-IRRIGATION-OF-CORPORA-CAVERNOSA-PRIAPISM

    CPT 54220: Irrigation of Corpora Cavernosa for Priapism

    CPT-54230-CAVERNOSOGRAPHY-VENOUS-LEAKAGE-EVALUATION

    CPT 54230: Cavernosography for Venous Leakage Evaluation

    CPT-54231-DYNAMIC-CAVERNOSOMETRY-WITH-PHARMACOLOGIC-INJECTION

    CPT 54231: Dynamic Cavernosometry with Intracavernosal Injection

    CPT-54235-INTRACAVERNOSAL-PHARMACOLOGIC-INJECTION-FOR-ED

    CPT 54235: Intracavernosal Injection for Erectile Dysfunction

    CPT-54240-PENILE-PLETHYSMOGRAPHY-ERECTILE-DYSFUNCTION-ASSESSMENT

    CPT 54240: Penile Plethysmography for Erectile Dysfunction Assessment

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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