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    OpenPayerBilling CodesIntroduction Procedures on the PenisCPT cpt-54220-irrigation-of-corpora-cavernosa-priapism
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    CPT 54220: Irrigation of Corpora Cavernosa for Priapism

    Medicare pays $260 on average nationally for this procedure.

    CPT code 54220 describes irrigation of the corpora cavernosa to treat priapism, a urologic procedure performed to relieve a prolonged erection; this is an operative/therapeutic procedure typically delivered in an emergency department or operating room setting where the provider accesses and irrigates the penile corpora cavernosa to decompress and restore normal penile blood flow.

    For related coverage guidance, see recent payer policy updates: Lymphedema - Surgical Treatment - Medical Policy, Breast Reduction (Mammoplasty) Surgery, Mastectomy Treatment, Breast Reconstruction and Mastectomy Hospital Stays Mandates.

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    Clinical & Coding Specifications

    Clinical Context

    A typical patient is an adult male who presents to the emergency department with a painful, persistent penile erection lasting more than four hours. Initial evaluation includes history, focused genitourinary exam, penile Doppler ultrasound if available to distinguish ischemic (low-flow) from non-ischemic (high-flow) priapism, and baseline labs including complete blood count and coagulation studies. For ischemic priapism unresponsive to conservative measures (oral or intracavernosal sympathomimetic agents), the urology team performs bedside or procedure-room aspiration and irrigation of the corpora cavernosa to relieve trapped blood and restore perfusion. The procedure involves sterile preparation, local or regional anesthesia (or general anesthesia if needed), aspiration of blood from one or both corpora with a syringe and needle, irrigation with normal saline, and possible intracavernosal injection of sympathomimetic agent. Post-procedure monitoring includes pain control, assessment of detumescence, and instructions regarding follow-up and potential penile vascular evaluation if priapism recurs. Typical sites of service are the emergency department, hospital inpatient bed, or ambulatory procedure room depending on acuity and anesthesia needs.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    54210Evacuation of hematoma from penis; simpleMay be performed if penile hematoma complicates priapism management or after incision for shunt creation.
    54050Frenuloplasty; simpleSeparate penile procedures that may be performed in the same operative session for unrelated pathology (rarely directly related).
    54416Shunt procedure, penile (for treatment of priapism); cavernoso-spongiosal shunt (Quackel)Performed when irrigation/aspiration fails to resolve ischemic priapism; surgical shunt creates drainage to relieve priapism.
    54235Correction of buried penisDifferent penile surgical repair code; listed as potentially performed in same specialty but not directly related clinically.
    99284Emergency department visit, high severityTypical ED evaluation code that may be reported for the initial assessment leading to this procedure.

    Note: If a code above is not applicable in a specific encounter, report only procedures and evaluation services documented in the medical record.

    Related Modifiers

    13 rows

    ModifierDescriptionWhen to Use
    23Modifier -23 (Unusual Anesthesia) is used on anesthesia service CPT codes when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia…- Use modifier -23 only on anesthesia CPT codes (00100–01999) when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia because of…
    26Modifier 26 (Professional Component) identifies and bills only the professional portion of a split service — the physician’s interpretation, report, and medical judgment — when the technical…- Use CPT Modifier -26 when you are billing only the professional component (PC) of a split‑bill eligible service—i.e., you performed the physician interpretation, medical judgment and prepared a…
    50Modifier –50 (Bilateral Procedure) is appended to a CPT code when an identical procedure is performed on paired anatomical structures during the same operative session. The AMA states to add…- Use modifier -50 when the same CPT surgical, diagnostic, or radiology procedure is performed on paired anatomical structures (both sides of the body) during the same operative/session by the same…
    51Modifier –51 (Multiple Procedures) is used when the same provider performs multiple procedures in the same session to identify secondary, non‑exempt procedures and indicate payment reduction logic…- Use modifier -51 when the same provider performs multiple distinct procedures during the same patient encounter: report the highest‑valued procedure first (no modifier) and append -51 to…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    59Modifier 59 indicates a distinct procedural service when two procedures that are not normally billed together are clinically and procedurally separate. The CPT definition (as reiterated by CMS)…- Use modifier -59 to report a distinct procedural service when documentation supports that the procedure reported is not normally billed together with another service on the same day because of a…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
    76Modifier -76, Repeat Procedure or Service by Same Physician or Other Qualified Health Care Professional, is appended when the same provider performs an identical, medically necessary procedure or…- Use modifier -76 when the same physician or other qualified health care professional performs an identical procedure or service a second (or subsequent) time on the same date of service and the…
    77Modifier 77 indicates that a previously performed procedure or service was legitimately repeated by a different physician or other qualified health care professional. The AMA’s CPT definition…- Use modifier 77 when a basic procedure or service already performed is repeated by a different physician or other qualified health care professional (for example, a second provider independently…

    Showing 1–10 of 13

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    2080P0207X
    208000000X
    207RH0000X
    276400000X
    282NR1301X
    207ZP0105X
    207VX0000X
    322D00000X

    Related ICD-10-CM Codes

    24 rows

    ICD-10-CM CodeDescription
    E10.9Type 1 diabetes mellitus without complications
    E11.9Type 2 diabetes mellitus without complications
    F10.20Alcohol dependence, uncomplicated
    F11.20Opioid dependence, uncomplicated
    G62.9Polyneuropathy, unspecified
    G82.20Paraplegia, unspecified
    G96.9Disorder of central nervous system, unspecified
    I95.1Orthostatic hypotension
    N48.89Other specified disorders of penis
    N48.9Disorder of penis, unspecified

    Showing 1–10 of 24

    Related Payer Policy Updates

    Specialty: Plastic/Reconstructive Surgery1 / 2

    10 rows

    PolicyPayerEffective Date
    Lymphedema - Surgical Treatment - Medical PolicyHealth-New-England2027-02-01
    Breast Reduction (Mammoplasty) SurgeryKaiser Permanente2027-02-01
    Mastectomy Treatment, Breast Reconstruction and Mastectomy Hospital Stays MandatesBlue Cross Blue Shield - Rhode Island2027-01-01
    Lipodystrophy Syndrome - HIV Associated - Medical PolicyHealth-New-England2026-12-01
    Abdominal Panniculectomy and Excision of Excessive Skin and Subcutaneous Tissue - Medical PolicyHealth-New-England2026-12-01
    Reduction MammaplastyBlue Cross Blue Shield - North Dakota2026-11-01
    Cosmetic and Reconstructive ProceduresAmbetter Georgia2026-11-01
    Surgical Treatment of Lipedema and Lymphedemahusky_health2026-11-01
    Rhinoplasty Medical Necessity and Site of ServicePremera Bluecross2026-10-14
    Reconstructive Breast Surgery/Mastopexy, and Management of Breast ImplantsBlue Cross Blue Shield - North Dakota2026-10-01

    Related Codes

    CPT-54200-PENILE-INJECTION-FOR-PEYRONIE-DISEASE

    CPT 54200: Intralesional Injection for Peyronie Disease

    CPT-54205-PENILE-PLAQUE-EXPOSURE-AND-INJECTION-FOR-PEYRONIE-DISEASE

    CPT 54205: Penile Plaque Exposure and Injection for Peyronie Disease

    CPT-54230-CAVERNOSOGRAPHY-VENOUS-LEAKAGE-EVALUATION

    CPT 54230: Cavernosography for Venous Leakage Evaluation

    CPT-54231-DYNAMIC-CAVERNOSOMETRY-WITH-PHARMACOLOGIC-INJECTION

    CPT 54231: Dynamic Cavernosometry with Intracavernosal Injection

    CPT-54235-INTRACAVERNOSAL-PHARMACOLOGIC-INJECTION-FOR-ED

    CPT 54235: Intracavernosal Injection for Erectile Dysfunction

    CPT-54240-PENILE-PLETHYSMOGRAPHY-ERECTILE-DYSFUNCTION-ASSESSMENT

    CPT 54240: Penile Plethysmography for Erectile Dysfunction Assessment

    CPT-54250-NOCTURNAL-PENILE-TUMESCENCE-NPT-MONITORING

    CPT 54250: Nocturnal Penile Tumescence (NPT) Testing

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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