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    OpenPayerBilling CodesIntroduction Procedures on the PenisCPT cpt-54231-dynamic-cavernosometry-with-pharmacologic-injection
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    CPT 54231: Dynamic Cavernosometry with Intracavernosal Injection

    Medicare pays $153 on average nationally for this procedure.

    CPT code 54231 describes dynamic cavernosometry with intracavernosal injection of vasoactive agents to measure corporaw cavernosa pressures, assess arterial inflow, and quantify venous leakage during induced erection; the service is a diagnostic vascular study of the penis typically performed by a urologist in an outpatient procedural suite or ambulatory surgery center under monitored conditions.

    For related coverage guidance, see recent payer policy updates: Lymphedema - Surgical Treatment - Medical Policy, Breast Reduction (Mammoplasty) Surgery, Mastectomy Treatment, Breast Reconstruction and Mastectomy Hospital Stays Mandates.

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    Clinical & Coding Specifications

    Clinical Context

    A 52-year-old male presents to a urology clinic with a 2-year history of persistent erectile dysfunction not responsive to oral phosphodiesterase-5 inhibitors. Prior noninvasive testing (penile Doppler ultrasound) suggests arterial inflow is preserved but there is concern for veno-occlusive dysfunction (venous leakage). The urologist recommends dynamic cavernosometry and cavernosography to measure intracavernosal pressure during pharmacologically induced erection and to quantify the severity and pattern of venous leak.

    The clinical workflow: the patient undergoes pre-procedure consent and medication review, baseline vital signs and penile Doppler review. In the procedure room, the provider places a small-gauge intracavernosal needle into the corpora cavernosa, measures resting intracavernosal pressure, then injects a vasoactive agent (eg, prostaglandin E1) to induce erection. Serial pressure measurements during erection are recorded. Dynamic cavernosography with radiographic contrast may follow to visualize venous outflow if indicated. Post-procedure monitoring includes hemostasis at the injection site, observation for priapism, and discharge instructions with analgesia and emergency contact information.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    54231Dynamic cavernosometry and intracavernosal injection of vasoactive agent to assess erectile functionPrimary procedure to measure intracavernosal pressure and diagnose venous leakage
    54235Cavernosography (radiographic visualization of corporal venous drainage)Often performed immediately after dynamic cavernosometry when venous leak is suspected to delineate venous anatomy
    54240Penile vascular surgery; venous ligation (deep dorsal vein or cavernosal veins)Surgical treatment option for clinically significant venous leak identified by cavernosometry/cavernosography
    54520Injection for diagnostic or therapeutic purposes into the penis (other than intracavernosal diagnostic studies)Related intracavernosal injection codes when performed for diagnostic testing or therapeutic injection
    93971Duplex ultrasound, arterial and venous evaluation of lower extremity arteries — bilateral; noninvasive physiologic vascular study (example similar noninvasive testing)Noninvasive vascular studies such as penile duplex ultrasound are commonly performed prior to invasive cavernosometry

    Related Modifiers

    9 rows

    ModifierDescriptionWhen to Use
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
    66Modifier 66 (Surgical Team) is used when three or more surgeons act as primary surgeons on a single, highly complex procedure. The AMA defines it for use when a surgical team — often composed of…- Use modifier 66 when three or more surgeons act as primary surgeons working collaboratively as a surgical team on a single, highly complex or difficult procedure (for example organ…
    76Modifier -76, Repeat Procedure or Service by Same Physician or Other Qualified Health Care Professional, is appended when the same provider performs an identical, medically necessary procedure or…- Use modifier -76 when the same physician or other qualified health care professional performs an identical procedure or service a second (or subsequent) time on the same date of service and the…
    78CPT modifier -78 indicates an unplanned, related return to the operating or procedure room by the same provider during the global postoperative period. It is appended when treatment for a…- Use modifier -78 when an unplanned, related complication during the original procedure’s global postoperative period requires the patient to return to a formal operating or procedure room and the…
    80CPT® Modifier 80 (Assistant Surgeon) is appended to a surgical CPT code when a physician (MD or DO) provides full, continuous assistance throughout the operative procedure. It is intended only for…- Use CPT Modifier -80 when a physician (MD or DO) serves as an assistant surgeon and provides full, continuous assistance throughout the entire operative procedure; append -80 to the surgical CPT…
    99Modifier 99 is a placeholder modifier used when more modifiers apply to a single procedure than the claim form or electronic field allows. The AMA classifies it under Provider Services and Ambulatory…- Use CPT modifier -99 when more modifiers apply to a single procedure line than the claim form or payer field allows (CMS/Noridian: when more than four modifiers are needed); append modifier 99 on…

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    208000000X
    208800000X
    207R00000X
    363L00000X
    2080P0206X
    363LC1500X
    251C00000X
    207ZI0100X

    Related Payer Policy Updates

    Specialty: Plastic/Reconstructive Surgery1 / 2

    10 rows

    PolicyPayerEffective Date
    Lymphedema - Surgical Treatment - Medical PolicyHealth-New-England2027-02-01
    Breast Reduction (Mammoplasty) SurgeryKaiser Permanente2027-02-01
    Mastectomy Treatment, Breast Reconstruction and Mastectomy Hospital Stays MandatesBlue Cross Blue Shield - Rhode Island2027-01-01
    Lipodystrophy Syndrome - HIV Associated - Medical PolicyHealth-New-England2026-12-01
    Abdominal Panniculectomy and Excision of Excessive Skin and Subcutaneous Tissue - Medical PolicyHealth-New-England2026-12-01
    Reduction MammaplastyBlue Cross Blue Shield - North Dakota2026-11-01
    Cosmetic and Reconstructive ProceduresAmbetter Georgia2026-11-01
    Surgical Treatment of Lipedema and Lymphedemahusky_health2026-11-01
    Rhinoplasty Medical Necessity and Site of ServicePremera Bluecross2026-10-14
    Reconstructive Breast Surgery/Mastopexy, and Management of Breast ImplantsBlue Cross Blue Shield - North Dakota2026-10-01

    Related Codes

    CPT-54200-PENILE-INJECTION-FOR-PEYRONIE-DISEASE

    CPT 54200: Intralesional Injection for Peyronie Disease

    CPT-54205-PENILE-PLAQUE-EXPOSURE-AND-INJECTION-FOR-PEYRONIE-DISEASE

    CPT 54205: Penile Plaque Exposure and Injection for Peyronie Disease

    CPT-54220-IRRIGATION-OF-CORPORA-CAVERNOSA-PRIAPISM

    CPT 54220: Irrigation of Corpora Cavernosa for Priapism

    CPT-54230-CAVERNOSOGRAPHY-VENOUS-LEAKAGE-EVALUATION

    CPT 54230: Cavernosography for Venous Leakage Evaluation

    CPT-54235-INTRACAVERNOSAL-PHARMACOLOGIC-INJECTION-FOR-ED

    CPT 54235: Intracavernosal Injection for Erectile Dysfunction

    CPT-54240-PENILE-PLETHYSMOGRAPHY-ERECTILE-DYSFUNCTION-ASSESSMENT

    CPT 54240: Penile Plethysmography for Erectile Dysfunction Assessment

    CPT-54250-NOCTURNAL-PENILE-TUMESCENCE-NPT-MONITORING

    CPT 54250: Nocturnal Penile Tumescence (NPT) Testing

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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