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    v1.0.30
    OpenPayerBilling CodesExcision Procedures on the KidneyCPT cpt-50290-excision-kidney-surrounding-tissue-cyst
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    CPT 50290: Excision of Perirenal Cyst

    Medicare pays $824 on average nationally for this procedure.

    CPT code 50290 describes an excision of a cyst from the tissue surrounding the kidney, a surgical procedure to remove a perirenal cyst; the service is a surgical excision typically performed in an operating room or ambulatory surgery center and involves removal of cystic tissue adjacent to the kidney to address symptoms or diagnostic concerns.

    For related coverage guidance, see recent payer policy updates: Surgical Procedures, Outpatient Surgical Procedures - Site of Service, Site of Service Ambulatory Service Center (ASC) Select — Surgical or Diagnostic Procedures in Adults.

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    Table of contents

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    Clinical & Coding Specifications

    Clinical Context

    A 52-year-old patient presents with intermittent flank pain and an incidentally noted perirenal cyst on abdominal imaging. The urologist evaluates imaging (CT or ultrasound) that localizes a symptomatic cyst arising from the perinephric tissues. After informed consent, the patient is scheduled for an operative excision of the cyst under general anesthesia. Intraoperative workflow includes surgical exposure of the retroperitoneum, identification of the cystic lesion adjacent to the kidney, careful dissection to separate the cyst from renal capsule and surrounding structures, removal of the cyst wall, hemostasis, and placement of drains if indicated. Specimens are sent to pathology when indicated. Postoperative monitoring occurs in the PACU with routine pain control, wound care instructions, and follow-up imaging or clinic visit to assess healing and rule out recurrence or complications such as bleeding or infection.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    50260Renal biopsy, percutaneous, needle; unilateralMay be performed preoperatively for tissue diagnosis of a suspicious perirenal lesion prior to excision.
    50590Unilateral nephrectomy, including partial or complete excision of kidney for other indicationsPerformed when cyst involves or cannot be separated from renal parenchyma, necessitating partial or complete nephrectomy.
    54150Circumcision, procedure code example unrelated — placeholder not usedData not applicable; included only if clinically indicated (not typical for renal procedures).

    Related Modifiers

    8 rows

    ModifierDescriptionWhen to Use
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
    66Modifier 66 (Surgical Team) is used when three or more surgeons act as primary surgeons on a single, highly complex procedure. The AMA defines it for use when a surgical team — often composed of…- Use modifier 66 when three or more surgeons act as primary surgeons working collaboratively as a surgical team on a single, highly complex or difficult procedure (for example organ…
    78CPT modifier -78 indicates an unplanned, related return to the operating or procedure room by the same provider during the global postoperative period. It is appended when treatment for a…- Use modifier -78 when an unplanned, related complication during the original procedure’s global postoperative period requires the patient to return to a formal operating or procedure room and the…
    80CPT® Modifier 80 (Assistant Surgeon) is appended to a surgical CPT code when a physician (MD or DO) provides full, continuous assistance throughout the operative procedure. It is intended only for…- Use CPT Modifier -80 when a physician (MD or DO) serves as an assistant surgeon and provides full, continuous assistance throughout the entire operative procedure; append -80 to the surgical CPT…
    81Modifier -81 indicates a physician served as a minimal assistant surgeon for part—not all—of an operative procedure. Use when a physician’s assisting role is limited and does not represent full…- Use CPT modifier -81 when a physician acts as a minimum assistant surgeon who assists during only part (a limited portion) of an operative procedure; append -81 to the primary surgical CPT code to…

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    2082S0105X
    152WS0006X
    226000000X
    146N00000X
    2471R0002X
    1041S0200X
    246RH0600X
    2084P0800X

    Related Payer Policy Updates

    Specialty: General Surgery1 / 2

    10 rows

    PolicyPayerEffective Date
    Surgical ProceduresUnitedHealthcare2026-09-01
    Outpatient Surgical Procedures - Site of ServiceUnitedHealthcare2026-09-01
    Site of Service Ambulatory Service Center (ASC) Select — Surgical or Diagnostic Procedures in AdultsPremera Bluecross2026-09-01
    Site of Service Ambulatory Surgical Center (ASC) Select — Surgical or Diagnostic Procedures in AdultsPremera Bluecross2026-09-01
    Site of Service Ambulatory Service Center (ASC) SelectPremera Bluecross2026-09-01
    Site of Service Ambulatory Surgical Center (ASC) Select — Site of Service for Ambulatory Surgical Procedures (ASC Select)Premera Bluecross2026-09-01
    Site of Service Ambulatory Service Center (ASC) SelectPremera Bluecross2026-09-01
    Outpatient Surgical Procedures - Site of Servicesierra health and life2026-08-01
    Medical Necessity Guidelines — Inpatient Surgical CareMass General Brigham Health Plan2026-08-01
    Ambulatory Surgery Center (ASC) - Site of Care PolicyKaiser Permanente2026-08-01

    Related Codes

    CPT-50200-PERCUTANEOUS-RENAL-ASPIRATION-DIAGNOSTIC-BIOPSY

    CPT 50200: Percutaneous Renal Needle Biopsy

    CPT-50205-PERCUTANEOUS-KIDNEY-BIOPSY-SAMPLING

    CPT 50205: Kidney Needle Collection for Diagnostic Biopsy

    CPT-50220-NEPHRECTOMY-KIDNEY-REMOVAL

    CPT 50220: Partial or Complete Nephrectomy, Kidney Removal

    CPT-50225-NEPHRECTOMY-KIDNEY-REMOVAL

    CPT 50225: Nephrectomy (Kidney Removal)

    CPT-50230-NEPHRECTOMY-KIDNEY-REMOVAL

    CPT 50230: Nephrectomy, Kidney Removal

    CPT-50234-NEPHRECTOMY-KIDNEY-REMOVAL

    CPT 50234: Nephrectomy, Kidney Removal

    CPT-50236-NEPHRECTOMY-KIDNEY-REMOVAL

    CPT 50236: Nephrectomy (Kidney Removal)

    CPT-50240-NEPHRECTOMY-KIDNEY-REMOVAL

    CPT 50240: Nephrectomy, Kidney Removal

    CPT-50250-KIDNEY-CRYOABLATION-CRYOSURGERY

    CPT 50250: Kidney Cryoablation/Cryosurgery

    CPT-50280-RENAL-CYST-EXCISION-OPEN-DEROOFING

    CPT 50280: Excision/Removal of Renal Surface Cyst(s)

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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