Loading...

    Explore
    • Policy Monitoring
    • Live Policy Feed
    • Billing Codes
    • NPI Medicare & Medicaid
    • Healthcare Providers
    • Health Insurance Payers
    • States
    • Service Lines
    • Taxonomy Codes
    Lookup tools
    • Billing Code Lookup
    • CPT Modifier Lookup
    • Provider Taxonomy Code Lookup
    • Healthcare Provider & Facility Lookup
    • Health Insurance Payer Lookup
    • Payer Contact Directory

    Policy & Benchmark Tools

    • Prior Authorization Lookup
    • Coverage Criteria Lookup
    • Timely Filing Lookup
    • Billing Code Reimbursement Rates
    • Payer Comparison Dashboard
    • Facility Comparison Dashboard
    • All tools

    Company

    • About OpenPayer
    • Data Sources
    • Trek Health
    OpenPayerby Trek Health
    LinkedInYouTube

    © 2026 Trek Health. All rights reserved.

    OpenPayer is built and maintained by Trek Health.

    v1.0.28
    OpenPayerBilling CodesMalignant neoplasms of mesothelial and soft tissueICD-10-CM c46-kaposis-sarcoma
    Ask Trek AI about this page

    ICD-10-CM Code For Kaposi's Sarcoma: Group Overview

    The International Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM) code group C46 includes malignant vascular tumors known as Kaposi's sarcoma, encompassing skin, mucosal, and visceral presentations, including classic, endemic, iatrogenic, and epidemic forms. These ICD-10-CM diagnosis codes are used to document clinical scenarios such as localized skin lesions, multifocal disease with mucosal or visceral involvement, and immune-status–related presentations that capture disease severity and organ involvement. Accurate coding within the ICD-10-CM C46 group supports proper claim adjudication and complete clinical documentation and appropriate reimbursement.

    Customize your policy alerts

    Sign up for ICD-10-CM Code For Kaposi's Sarcoma: Group Overview policy alerts

    Get alerted when relevant policies change without checking for updates manually.

    Monitor payer policy activity

    Receive email alerts as soon as relevant payer policies are published or updated.

    ICD-10-CM C46: Kaposi's Sarcoma Overview

    Kaposi's sarcoma represents a group of vascular tumors caused by human herpesvirus 8 infection that primarily affect skin, mucous membranes, and sometimes visceral organs. These diagnoses target the integumentary and lymphatic systems as well as potential internal organ involvement. Accurate coding is important for reflecting disease extent and complexity, which affects clinical records and reimbursement.

    Table of contents

    Progress1 / 6

    Explore openpayer tools

    • Billing CodesCPT, HCPCS, DRG & more
    • Reimbursement RatesCommercial vs. Medicare rate reports
    • ProvidersHospitals & facilities
    • PayersPlans & market footprint
    • Taxonomy CodesNUCC specialty codes
    • ModifiersCPT modifiers & usage
    • Prior AuthorizationPA policies by payer & drug
    • Timely FilingFiling deadlines by payer
    • Coverage CriteriaMedical necessity by payer
    • Payer ContactsClaims, PA & appeals contacts
    View all tools

    When to Use

    Use a code from this group when a clinician documents Kaposi's sarcoma as the diagnosis, specifying site and any associated visceral or lymphatic involvement. Select the appropriate specific code to reflect disease distribution and clinical context, such as immune-suppressed states or transplant-related disease.

    ICD-10-CM Codes

    10 rows

    ICD-10-CM CodeDescription
    C46.0Kaposi's sarcoma of skin
    C46.1Kaposi's sarcoma of soft tissue
    C46.2Kaposi's sarcoma of palate
    C46.3Kaposi's sarcoma of lymph nodes
    C46.4Kaposi's sarcoma of gastrointestinal sites
    C46.50Kaposi's sarcoma of unspecified lung
    C46.51Kaposi's sarcoma of right lung
    C46.52Kaposi's sarcoma of left lung
    C46.7Kaposi's sarcoma of other sites
    C46.9Kaposi's sarcoma, unspecified

    DRG Codes

    26 rows

    DRG CodeDescription
    011Tracheostomy for Face, Mouth and Neck Diagnoses or Laryngectomy with MCC
    012Tracheostomy for Face, Mouth and Neck Diagnoses or Laryngectomy with CC
    013Tracheostomy for Face, Mouth and Neck Diagnoses or Laryngectomy without CC/MCC
    146Ear, Nose, Mouth and Throat Malignancy with MCC
    147Ear, Nose, Mouth and Throat Malignancy with CC
    148Ear, Nose, Mouth and Throat Malignancy without CC/MCC
    180Respiratory Neoplasms with MCC
    181Respiratory Neoplasms with CC
    182Respiratory Neoplasms without CC/MCC
    374Digestive Malignancy with MCC
    375Digestive Malignancy with CC
    376Digestive Malignancy without CC/MCC
    606Minor Skin Disorders with MCC
    607Minor Skin Disorders without MCC
    820Lymphoma and Leukemia with Major O.R. Procedures with MCC
    821Lymphoma and Leukemia with Major O.R. Procedures with CC
    822Lymphoma and Leukemia with Major O.R. Procedures without CC/MCC
    823Lymphoma and Non-Acute Leukemia with Other Procedures with MCC
    824Lymphoma and Non-Acute Leukemia with Other Procedures with CC
    825Lymphoma and Non-Acute Leukemia with Other Procedures without CC/MCC

    Showing 1–20 of 26

    Typical Clinical Scenarios

    • An older adult with HIV/AIDS presents to clinic with multiple violaceous, non-blanching papules and plaques on the lower extremities and oral mucosa that have progressively enlarged over months; biopsy confirms spindle-cell vascular tumor consistent with Kaposi sarcoma and staging evaluates for visceral involvement. A diagnosis from this group is assigned to specify the anatomic site(s) of the malignant lesion for treatment planning and coding. Typical codes: C46.0, C46.3
    • A young person with known pulmonary symptoms (dyspnea and cough) is hospitalized after imaging shows nodular masses in the lung and bronchoscopy with biopsy demonstrates Kaposi sarcoma of the respiratory tract; management focuses on supportive care and oncologic therapy. A code from this group is used to record the visceral respiratory involvement of the malignancy. Typical codes: C46.2, C46.9
    • A patient with long-standing cutaneous Kaposi sarcoma develops lymphedema and secondary infection of the affected limb, prompting urgent clinic visit for wound care and infection control; the visit documents the malignant skin lesions as the underlying cause of the edema and infection. Coding uses a code from this group to identify the primary malignant neoplasm as a comorbidity contributing to the complication. Typical codes: C46.1, C46.7

    Related Codes

    C45-MESOTHELIOMA

    ICD-10-CM Code For Mesothelioma: Group Overview

    C47-MALIGNANT-NEOPLASM-PERIPHERAL-NERVES

    ICD-10-CM Code For Malignant Neoplasm Of Peripheral Nerves And Autonomic Nervous System: Group Overview

    C48-MALIGNANT-NEOPLASM-RETROPERITONEUM-PERITONEUM

    ICD-10-CM Code For Malignant Neoplasm Of Retroperitoneum And Peritoneum: Group Overview

    C49-MALIGNANT-NEOPLASM-OF-SOFT-TISSUE

    ICD-10-CM Code For Malignant Neoplasm Of Other Connective And Soft Tissue: Group Overview

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
    Published by

    Trek Health powers OpenPayer with a leading commercial payer intelligence platform, seamlessly converting fragmented payer data into actionable insights for provider organizations.

    Trek Health ingests and normalizes Transparency in Coverage data and payer policy updates to give provider organizations a clear view of how commercial reimbursement behaves across markets, payers, and services. Our platform transforms raw payer disclosures into structured intelligence that supports contract evaluation, payer negotiations, and service line strategy. By combining market benchmarks with ongoing policy visibility, Trek helps teams identify variability, risk, and opportunity in commercial reimbursement. The result is faster insight, stronger negotiating positions, and more informed financial decisions.