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    OpenPayerBilling CodesHemorrhagic and hematological disorders of newbornICD-10-CM p57-kernicterus-and-neonatal-jaundice
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    ICD-10-CM Code For Kernicterus: Group Overview

    The International Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM) code group P57 includes diagnoses for kernicterus and bilirubin-induced neurologic dysfunction in newborns, covering acute and chronic neurologic damage caused by severe neonatal hyperbilirubinemia. These ICD-10-CM diagnosis codes are used to document neonatal neurologic injury from elevated bilirubin levels, capturing clinical severity, neurologic involvement, and chronic sequelae relevant to this group. Accurate coding within the ICD-10-CM P57 group supports proper claim adjudication, complete clinical documentation, and appropriate reimbursement.

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    ICD-10-CM P57: Kernicterus Overview

    The ICD-10-CM P57 group represents kernicterus and related bilirubin-induced neurologic dysfunction in newborns, targeting neonatal neurologic injury due to severe hyperbilirubinemia. These diagnoses affect the central nervous system in the neonate and can result in long-term motor and cognitive impairments. Accurate coding matters for correct severity reporting and appropriate reimbursement for neonatal care and long-term follow-up.

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    When to Use

    Use a code from this group when a newborn has documented neurologic injury attributable to elevated bilirubin levels, including both acute encephalopathy and chronic dysfunction. Codes are appropriate when clinical notes or diagnostic testing link neurologic signs or long-term sequelae directly to neonatal hyperbilirubinemia.

    ICD-10-CM Codes

    3 rows

    ICD-10-CM CodeDescription
    P57.0Kernicterus due to isoimmunization
    P57.8Other specified kernicterus
    P57.9Kernicterus, unspecified

    DRG Codes

    2 rows

    DRG CodeDescription
    791Prematurity with Major Problems
    793Full Term Neonate with Major Problems

    Typical Clinical Scenarios

    • A newborn term infant presents in the nursery on day 3 with progressive jaundice, lethargy, poor feeding, hypertonia and intermittent upward gaze after previously rising bilirubin levels despite phototherapy; neonatology documents bilirubin-induced neurologic dysfunction with kernicterus features and orders neuroimaging and exchange transfusion consideration. A diagnosis from this group is assigned to indicate bilirubin encephalopathy complicating the neonatal course. Typical codes: P57.0
    • An infant with a history of prematurity and prolonged hemolytic disease of the newborn is followed in outpatient neurology at 6 months for developmental delay, sensorineural hearing loss, and choreoathetoid movements attributed to prior bilirubin brain injury; the clinician codes the visit to reflect chronic sequelae of neonatal bilirubin encephalopathy. Typical codes: P57.8, P57.9
    • A neonate transferred emergently from a community hospital with acute bilirubin encephalopathy after late-presenting severe hyperbilirubinemia, requiring intensive care, temperature-controlled phototherapy, and consideration of exchange transfusion; coding captures the acute bilirubin-induced neurologic disorder complicating the newborn admission. Typical codes: P57.0

    Related Codes

    P50-NEWBORN-AFFECTED-BY-INTRAUTERINE-BLOOD-LOSS

    ICD-10-CM Code For Newborn Affected By Intrauterine Blood Loss: Group Overview

    P51-UMBILICAL-HEMORRHAGE-OF-NEWBORN

    ICD-10-CM Code For Umbilical Hemorrhage Of Newborn: Group Overview

    P52-INTRACRANIAL-HEMORRHAGE-NEWBORN

    ICD-10-CM Code For Intracranial Nontraumatic Hemorrhage Of Newborn: Group Overview

    P53-HEMORRHAGIC-DISEASE-OF-NEWBORN

    ICD-10-CM Code For Hemorrhagic Disease Of Newborn: Group Overview

    P54-OTHER-NEONATAL-HEMORRHAGES

    ICD-10-CM Code For Other Neonatal Hemorrhages: Group Overview

    P56-HYDROPS-FETALIS-DUE-TO-HEMOLYTIC-DISEASE

    ICD-10-CM Code For Hydrops Fetalis Due To Hemolytic Disease: Group Overview

    P59-NEONATAL-JAUNDICE-OTHER-UNSPECIFIED

    ICD-10-CM Code For Neonatal Jaundice From Other And Unspecified Causes: Group Overview

    P60-DISSEMINATED-INTRAVASCULAR-COAGULATION-NEWBORN

    ICD-10-CM Code For Disseminated Intravascular Coagulation Of Newborn: Group Overview

    P61-OTHER-PERINATAL-HEMATOLOGICAL-DISORDERS

    ICD-10-CM Code For Other Perinatal Hematological Disorders: Group Overview

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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