ICD-10-CM Code For Hemorrhagic Disease Of Newborn: Group Overview

The International Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM) code group P53 includes diagnoses for hemorrhagic disease of the newborn, encompassing bleeding disorders in neonates primarily due to vitamin K deficiency and related hemorrhagic conditions. These ICD-10-CM diagnosis codes are used to document clinical scenarios such as neonatal mucosal, gastrointestinal, or intracranial bleeding, capturing disease severity and bleeding site involvement relevant to this group. Accurate coding within the ICD-10-CM P53 group supports proper claim adjudication / complete clinical documentation / appropriate reimbursement.

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ICD-10-CM P53: Hemorrhagic Disease Of Newborn Overview

The ICD-10-CM P53 group captures hemorrhagic disease of the newborn, a bleeding disorder of the neonatal period related to vitamin K deficiency and related coagulopathies. These conditions affect the hematologic system and present with bleeding from mucous membranes, gastrointestinal tract, or intracranial sites. Accurate coding matters for proper clinical documentation and reimbursement because it reflects disease severity and informs neonatal care and claim adjudication.

When to Use

Use codes from this group when a neonate presents with documented bleeding attributed to vitamin K deficiency or other neonatal coagulopathies during the newborn period. Apply the specific code that reflects timing, severity, and anatomic site of the hemorrhage as documented in the medical record.

ICD-10-CM Codes

1 rows

ICD-10-CM Code	Description
P53	Hemorrhagic disease of newborn

DRG Codes

2 rows

DRG Code	Description
791	Prematurity with Major Problems
793	Full Term Neonate with Major Problems

Typical Clinical Scenarios

A full-term infant born at a community hospital presents within the first 48 hours of life with unexpected diffuse petechiae and ecchymoses, a prolonged bleeding umbilical stump, and declining hematocrit despite no maternal anticoagulant exposure; the neonate is admitted to the newborn nursery for laboratory evaluation and supportive care, and a diagnosis from this group is assigned to reflect hemorrhagic disease of the newborn as the cause of early bleeding. Typical codes: P53
A 2-week-old exclusively breastfed infant is brought to the emergency department with new-onset cephalohematoma and intracranial hemorrhage confirmed on head imaging after an episode of irritability and lethargy; there is no evidence of trauma, and maternal vitamin K prophylaxis at birth was not documented, prompting assignment of a code from this group to indicate late-onset hemorrhagic disease of the newborn. Typical codes: P53
A premature infant in the NICU with multiple comorbidities (including sepsis and thrombocytopenia) develops unexplained bleeding from venipuncture sites and gastrointestinal bleeding while receiving respiratory support; clinicians assign a code from this group to capture hemorrhagic disease of the newborn as a concurrent bleeding disorder contributing to the infant’s complications and management. Typical codes: P53

ICD-10-CM Code For Newborn Affected By Intrauterine Blood Loss: Group Overview

P51-UMBILICAL-HEMORRHAGE-OF-NEWBORN

ICD-10-CM Code For Umbilical Hemorrhage Of Newborn: Group Overview

P52-INTRACRANIAL-HEMORRHAGE-NEWBORN

ICD-10-CM Code For Intracranial Nontraumatic Hemorrhage Of Newborn: Group Overview

P54-OTHER-NEONATAL-HEMORRHAGES

ICD-10-CM Code For Other Neonatal Hemorrhages: Group Overview

P56-HYDROPS-FETALIS-DUE-TO-HEMOLYTIC-DISEASE

ICD-10-CM Code For Hydrops Fetalis Due To Hemolytic Disease: Group Overview

P57-KERNICTERUS-AND-NEONATAL-JAUNDICE

ICD-10-CM Code For Kernicterus: Group Overview

P59-NEONATAL-JAUNDICE-OTHER-UNSPECIFIED

ICD-10-CM Code For Neonatal Jaundice From Other And Unspecified Causes: Group Overview

P60-DISSEMINATED-INTRAVASCULAR-COAGULATION-NEWBORN

ICD-10-CM Code For Disseminated Intravascular Coagulation Of Newborn: Group Overview

P61-OTHER-PERINATAL-HEMATOLOGICAL-DISORDERS

ICD-10-CM Code For Other Perinatal Hematological Disorders: Group Overview

Frequently Asked Questions

References

1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.

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When to Use

ICD-10-CM Codes

1 rows

ICD-10-CM Code	Description
P53	Hemorrhagic disease of newborn

DRG Codes

2 rows

DRG Code	Description
791	Prematurity with Major Problems
793	Full Term Neonate with Major Problems

Typical Clinical Scenarios

A full-term infant born at a community hospital presents within the first 48 hours of life with unexpected diffuse petechiae and ecchymoses, a prolonged bleeding umbilical stump, and declining hematocrit despite no maternal anticoagulant exposure; the neonate is admitted to the newborn nursery for laboratory evaluation and supportive care, and a diagnosis from this group is assigned to reflect hemorrhagic disease of the newborn as the cause of early bleeding. Typical codes: P53
A 2-week-old exclusively breastfed infant is brought to the emergency department with new-onset cephalohematoma and intracranial hemorrhage confirmed on head imaging after an episode of irritability and lethargy; there is no evidence of trauma, and maternal vitamin K prophylaxis at birth was not documented, prompting assignment of a code from this group to indicate late-onset hemorrhagic disease of the newborn. Typical codes: P53
A premature infant in the NICU with multiple comorbidities (including sepsis and thrombocytopenia) develops unexplained bleeding from venipuncture sites and gastrointestinal bleeding while receiving respiratory support; clinicians assign a code from this group to capture hemorrhagic disease of the newborn as a concurrent bleeding disorder contributing to the infant’s complications and management. Typical codes: P53

ICD-10-CM Code For Newborn Affected By Intrauterine Blood Loss: Group Overview

P51-UMBILICAL-HEMORRHAGE-OF-NEWBORN

ICD-10-CM Code For Umbilical Hemorrhage Of Newborn: Group Overview

P52-INTRACRANIAL-HEMORRHAGE-NEWBORN

ICD-10-CM Code For Intracranial Nontraumatic Hemorrhage Of Newborn: Group Overview

P54-OTHER-NEONATAL-HEMORRHAGES

ICD-10-CM Code For Other Neonatal Hemorrhages: Group Overview

P56-HYDROPS-FETALIS-DUE-TO-HEMOLYTIC-DISEASE

ICD-10-CM Code For Hydrops Fetalis Due To Hemolytic Disease: Group Overview

P57-KERNICTERUS-AND-NEONATAL-JAUNDICE

ICD-10-CM Code For Kernicterus: Group Overview

P59-NEONATAL-JAUNDICE-OTHER-UNSPECIFIED

ICD-10-CM Code For Neonatal Jaundice From Other And Unspecified Causes: Group Overview

P60-DISSEMINATED-INTRAVASCULAR-COAGULATION-NEWBORN

ICD-10-CM Code For Disseminated Intravascular Coagulation Of Newborn: Group Overview

P61-OTHER-PERINATAL-HEMATOLOGICAL-DISORDERS

ICD-10-CM Code For Other Perinatal Hematological Disorders: Group Overview

Frequently Asked Questions

References

1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.

Published by

Trek Health powers OpenPayer with a leading commercial payer intelligence platform, seamlessly converting fragmented payer data into actionable insights for provider organizations.

ICD-10-CM Code For Hemorrhagic Disease Of Newborn: Group Overview

Sign up for ICD-10-CM Code For Hemorrhagic Disease Of Newborn: Group Overview policy alerts

ICD-10-CM P53: Hemorrhagic Disease Of Newborn Overview

ICD-10-CM Code For Hemorrhagic Disease Of Newborn: Group Overview

Sign up for ICD-10-CM Code For Hemorrhagic Disease Of Newborn: Group Overview policy alerts

ICD-10-CM P53: Hemorrhagic Disease Of Newborn Overview

When to Use

ICD-10-CM Codes

DRG Codes

Typical Clinical Scenarios

Related Codes

References

When to Use

ICD-10-CM Codes

DRG Codes

Typical Clinical Scenarios

Related Codes

References

ICD-10-CM Code For Hemorrhagic Disease Of Newborn: Group Overview

Sign up for ICD-10-CM Code For Hemorrhagic Disease Of Newborn: Group Overview policy alerts

ICD-10-CM P53: Hemorrhagic Disease Of Newborn Overview

ICD-10-CM Code For Hemorrhagic Disease Of Newborn: Group Overview

Sign up for ICD-10-CM Code For Hemorrhagic Disease Of Newborn: Group Overview policy alerts

ICD-10-CM P53: Hemorrhagic Disease Of Newborn Overview

When to Use

ICD-10-CM Codes

DRG Codes

Typical Clinical Scenarios

Related Codes

What conditions are included in the ICD-10-CM P53 group?

Why is accurate coding of `P53` important for billing and clinical documentation?

Which DRGs are related to the `P53` hemorrhagic disease of newborn group?

What types of bleeding presentations are noted within `ICD-10-CM P53`?

Does the P53 group specify the underlying cause of neonatal bleeding?

References

When to Use

ICD-10-CM Codes

DRG Codes

Typical Clinical Scenarios

Related Codes

What conditions are included in the ICD-10-CM P53 group?

Why is accurate coding of `P53` important for billing and clinical documentation?

Which DRGs are related to the `P53` hemorrhagic disease of newborn group?

What types of bleeding presentations are noted within `ICD-10-CM P53`?

Does the P53 group specify the underlying cause of neonatal bleeding?

References