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    v1.0.28
    OpenPayerBilling CodesRenal tubulo-interstitial diseasesICD-10-CM n10-acute-pyelonephritis
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    ICD-10-CM Code For Acute Pyelonephritis: Group Overview

    The International Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM) code group N10 includes acute bacterial infections of the renal pelvis and kidney parenchyma, commonly described as acute pyelonephritis, and covers presentations with varying severity and complications related to renal tubulo-interstitial inflammation. These ICD-10-CM diagnosis codes are used to document clinical encounters for acute upper urinary tract infections, capturing disease severity, organ involvement, and clinical complexity relevant to this group. Accurate coding within the ICD-10-CM N10 group supports proper claim adjudication, complete clinical documentation, and appropriate reimbursement.

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    ICD-10-CM N10: Acute Pyelonephritis Overview

    The ICD-10-CM N10 group represents acute bacterial infection of the renal pelvis and kidney tissue, commonly referred to as acute pyelonephritis, affecting the urinary tract and renal parenchyma. These diagnoses target renal tubulo-interstitial infections and complications arising from ascending urinary tract infections. Accurate coding matters for appropriate clinical documentation and supports correct billing and reimbursement processes by capturing disease acuity and organ involvement.

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    When to Use

    Use a code from this group when a clinician documents acute pyelonephritis or an acute upper urinary tract infection involving the kidney with clinical signs such as fever, flank pain, or pyuria. Codes from this group apply when the encounter focuses on active infection of the renal parenchyma rather than lower urinary tract infections or chronic interstitial conditions.

    ICD-10-CM Codes

    1 rows

    ICD-10-CM CodeDescription
    N10Acute pyelonephritis

    DRG Codes

    4 rows

    DRG CodeDescription
    689Kidney and Urinary Tract Infections with MCC
    690Kidney and Urinary Tract Infections without MCC
    791Prematurity with Major Problems
    793Full Term Neonate with Major Problems

    Typical Clinical Scenarios

    • An adult woman presents to the emergency department with sudden onset high fever, rigors, flank pain on the right side, nausea, and urinary frequency. Urinalysis shows positive nitrites and leukocyte esterase with many white blood cells, and blood tests reveal leukocytosis; imaging excludes obstructing stones. A working diagnosis of acute bacterial infection of the renal parenchyma is made, so a code from this group is assigned. Typical codes: N10
    • An elderly male nursing home resident develops acute worsening of baseline confusion, new-onset fever, and suprapubic and flank tenderness after a recent urinary catheter placement; urinalysis and urine culture are consistent with a severe upper urinary tract infection. Because the clinical picture represents a new acute infection of the kidney rather than chronic tubulointerstitial disease, a code from this group is used to document the acute pyelonephritis episode. Typical codes: N10
    • A pregnant patient in the outpatient prenatal clinic reports fever, costovertebral angle tenderness, and dysuria; urine culture grows a uropathogen requiring urgent treatment to prevent maternal and fetal complications. The clinician documents an acute pyelonephritis episode to capture the acute infectious process and guide management decisions, so a code from this group is assigned. Typical codes: N10

    Related Codes

    N11-CHRONIC-TUBULO-INTERSTITIAL-NEPHRITIS

    ICD-10-CM Code For Chronic Tubulo-Interstitial Nephritis: Group Overview

    N12-TUBULO-INTERSTITIAL-NEPHRITIS

    ICD-10-CM Code For Tubulo-Interstitial Nephritis Not Specified As Acute Or Chronic: Group Overview

    N13-OBSTRUCTIVE-AND-REFLUX-UROPATHY

    ICD-10-CM Code For Obstructive And Reflux Uropathy: Group Overview

    N14-DRUG-AND-HEAVY-METAL-INDUCED-TUBULO-INTERSTITIAL-CONDITIONS

    ICD-10-CM Code For Drug- And Heavy-Metal-Induced Tubulo-Interstitial And Tubular Conditions: Group Overview

    N15-OTHER-RENAL-TUBULO-INTERSTITIAL-DISEASES

    ICD-10-CM Code For Other Renal Tubulo Interstitial Diseases: Group Overview

    N16-RENAL-TUBULO-INTERSTITIAL-DISORDERS

    ICD-10-CM Code For Renal Tubulo-Interstitial Disorders In Diseases Classified Elsewhere: Group Overview

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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