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    v1.0.28
    OpenPayerBilling CodesGlomerular diseasesICD-10-CM n05-unspecified-nephritic-syndrome
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    ICD-10-CM Code For Unspecified Nephritic Syndrome: Group Overview

    The International Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM) code group N05 includes unspecified nephritic syndrome diagnoses characterized by glomerular inflammation leading to hematuria, proteinuria, edema, and renal impairment. These ICD-10-CM diagnosis codes are used to document clinical presentations of nephritic pathology, capturing disease severity, organ involvement, and clinical complexity relevant to glomerular disease. Accurate coding within the ICD-10-CM N05 group supports proper claim adjudication, complete clinical documentation, and appropriate reimbursement.

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    ICD-10-CM N05: Unspecified Nephritic Syndrome Overview

    The diagnoses in this group represent nephritic syndrome presentations characterized by glomerular inflammation affecting the kidneys and often causing hematuria, proteinuria, edema, and hypertension. These conditions target the renal glomeruli within the genitourinary system and can reflect acute or chronic inflammatory processes. Accurate coding matters for reimbursement because it documents clinical severity and guides claims adjudication tied to nephrology care.

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    When to Use

    Use a code from this group when the clinical record documents nephritic syndrome without specification of the exact cause or histologic subtype. These codes apply when providers report glomerular inflammation with characteristic signs like hematuria, proteinuria, edema, or reduced renal function but do not assign a more specific ICD-10-CM glomerular diagnosis.

    ICD-10-CM Codes

    11 rows

    ICD-10-CM CodeDescription
    N05.0Unspecified nephritic syndrome with minor glomerular abnormality
    N05.1Unspecified nephritic syndrome with focal and segmental glomerular lesions
    N05.2Unspecified nephritic syndrome with diffuse membranous glomerulonephritis
    N05.3Unspecified nephritic syndrome with diffuse mesangial proliferative glomerulonephritis
    N05.4Unspecified nephritic syndrome with diffuse endocapillary proliferative glomerulonephritis
    N05.5Unspecified nephritic syndrome with diffuse mesangiocapillary glomerulonephritis
    N05.6Unspecified nephritic syndrome with dense deposit disease
    N05.7Unspecified nephritic syndrome with diffuse crescentic glomerulonephritis
    N05.8Unspecified nephritic syndrome with other morphologic changes
    N05.9Unspecified nephritic syndrome with unspecified morphologic changes
    N05.AUnspecified nephritic syndrome with C3 glomerulonephritis

    DRG Codes

    3 rows

    DRG CodeDescription
    698Other Kidney and Urinary Tract Diagnoses with MCC
    699Other Kidney and Urinary Tract Diagnoses with CC
    700Other Kidney and Urinary Tract Diagnoses without CC/MCC

    Typical Clinical Scenarios

    • An adult presents to the emergency department with sudden-onset swelling of the face and legs, dark cola-colored urine, hypertension, and oliguria over 48–72 hours following a recent streptococcal throat infection. Urinalysis shows hematuria with red blood cell casts and moderate proteinuria; serum creatinine is acutely elevated, suggesting an acute glomerular inflammatory process. A diagnosis from this group is assigned to capture the nephritic syndrome presentation and acute glomerular injury. Typical codes: N05.0, N05.1
    • A middle-aged patient in outpatient nephrology care has persistent microscopic hematuria, intermittent edema, and slowly worsening proteinuria over months with stable but reduced renal function; kidney biopsy demonstrates chronic proliferative changes consistent with a glomerular disease producing ongoing nephritic features. The chronic, non-acute course with biopsy-proven glomerular involvement prompts use of a code from this group to document the chronic nephritic condition and guide longitudinal care. Typical codes: N05.2, N05.9
    • A hospitalized patient with systemic lupus erythematosus develops new hypertension, active urinary sediment with red cell casts, and a rise in serum creatinine while receiving immunosuppressive therapy; this represents nephritic syndrome as a complication of their systemic autoimmune disease requiring escalation of management and monitoring. Coding from this group is used to indicate nephritic involvement as a comorbidity complicating the systemic condition and hospital course. Typical codes: N05.6, N05.8

    Related Codes

    N00-ACUTE-NEPHRITIC-SYNDROME

    ICD-10-CM Code For Acute Nephritic Syndrome: Group Overview

    N01-RAPIDLY-PROGRESSIVE-NEPHRITIC-SYNDROME

    ICD-10-CM Code For Rapidly Progressive Nephritic Syndrome: Group Overview

    N02-RECURRENT-AND-PERSISTENT-HEMATURIA

    ICD-10-CM Code For Recurrent And Persistent Hematuria: Group Overview

    N03-CHRONIC-NEPHRITIC-SYNDROME

    ICD-10-CM Code For Chronic Nephritic Syndrome: Group Overview

    N04-NEPHROTIC-SYNDROME

    ICD-10-CM Code For Nephrotic Syndrome: Group Overview

    N06-ISOLATED-PROTEINURIA-WITH-LESION

    ICD-10-CM Code For Isolated Proteinuria With Specified Morphological Lesion: Group Overview

    N07-HEREDITARY-NEPHROPATHY-NOT-ELSEWHERE-CLASSIFIED

    ICD-10-CM Code For Hereditary Nephropathy Not Elsewhere Classified: Group Overview

    N08-GLOMERULAR-DISORDERS-IN-DISEASES-CLASSIFIED-ELSEWHERE

    ICD-10-CM Code For Glomerular Disorders In Diseases Classified Elsewhere: Group Overview

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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