ICD-10-CM Code For Acute Nephritic Syndrome: Group Overview

The International Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM) code group N00 includes acute nephritic syndromes characterized by inflammatory glomerular diseases causing hematuria, proteinuria, edema, and varying degrees of renal impairment. These ICD-10-CM diagnosis codes are used to document acute presentations of glomerulonephritis and related inflammatory kidney conditions, capturing disease severity, organ involvement, or clinical complexity relevant to this group. Accurate coding within the ICD-10-CM N00 group supports proper claim adjudication, complete clinical documentation, and appropriate reimbursement.

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ICD-10-CM N00: Acute Nephritic Syndrome Overview

The International Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM) code group N00 represents acute nephritic syndromes characterized by sudden onset glomerular inflammation affecting the kidneys. These diagnoses target the renal glomeruli and often present with hematuria, proteinuria, edema, and reduced kidney function. Accurate coding matters for appropriate claim processing and reflects clinical severity and resource use tied to reimbursement.

When to Use

Use a code from this group for patients presenting with clinical or laboratory evidence of acute nephritic syndrome, including new hematuria, proteinuria, edema, and reduced renal function attributable to glomerular inflammation. Select the most specific code that reflects laterality, severity, and any documented underlying etiology when available to support accurate documentation and billing.

ICD-10-CM Codes

13 rows

ICD-10-CM Code	Description
N00.0	Acute nephritic syndrome with minor glomerular abnormality
N00.1	Acute nephritic syndrome with focal and segmental glomerular lesions
N00.2	Acute nephritic syndrome with diffuse membranous glomerulonephritis
N00.3	Acute nephritic syndrome with diffuse mesangial proliferative glomerulonephritis
N00.4	Acute nephritic syndrome with diffuse endocapillary proliferative glomerulonephritis
N00.5	Acute nephritic syndrome with diffuse mesangiocapillary glomerulonephritis
N00.6	Acute nephritic syndrome with dense deposit disease
N00.7	Acute nephritic syndrome with diffuse crescentic glomerulonephritis
N00.8	Acute nephritic syndrome with other morphologic changes
N00.9	Acute nephritic syndrome with unspecified morphologic changes
N00.A	Acute nephritic syndrome with C3 glomerulonephritis
N00.B1	Acute nephritic syndrome with idiopathic immune membranoproliferative glomerulonephritis (IC-MPGN)
N00.B2	Acute nephritic syndrome with secondary immune complex membranoproliferative glomerulonephritis (IC-MPGN)

DRG Codes

5 rows

DRG Code	Description
698	Other Kidney and Urinary Tract Diagnoses with MCC
699	Other Kidney and Urinary Tract Diagnoses with CC
700	Other Kidney and Urinary Tract Diagnoses without CC/MCC
791	Prematurity with Major Problems
793	Full Term Neonate with Major Problems

Typical Clinical Scenarios

An adult presents to the emergency department with sudden onset hematuria, oliguria, edema, hypertension, and rising serum creatinine over 48 hours after a recent streptococcal throat infection. Urinalysis shows red blood cell casts and nephritic-range proteinuria; the clinical picture is consistent with an acute postinfectious glomerulonephritis causing acute nephritic syndrome, so a code from this group is assigned to reflect the acute glomerular inflammatory process. Typical codes: N00.0, N00.1
A middle-aged patient with known rapidly progressive glomerulonephritis develops days-to-weeks of worsening renal function, heavy proteinuria, and active urinary sediment; they are admitted for biopsy-proven crescentic glomerulonephritis requiring urgent immunosuppressive therapy. Because the presentation is an acute nephritic process with crescent formation and rapidly declining GFR, an acute nephritic syndrome code from this group is used to capture the glomerular disease acuity and subtype. Typical codes: N00.2, N00.3
An elderly patient with systemic lupus erythematosus is seen in clinic for new hypertension, edema, and microscopic hematuria on routine labs; renal biopsy confirms lupus nephritis with an acute nephritic component superimposed on chronic changes. In this comorbidity scenario where chronic autoimmune kidney disease has an acute nephritic exacerbation, a code from this group is assigned to indicate the acute nephritic involvement of the glomeruli alongside the underlying disorder. Typical codes: N00.4, N00.9

ICD-10-CM Code For Rapidly Progressive Nephritic Syndrome: Group Overview

N02-RECURRENT-AND-PERSISTENT-HEMATURIA

ICD-10-CM Code For Recurrent And Persistent Hematuria: Group Overview

N03-CHRONIC-NEPHRITIC-SYNDROME

ICD-10-CM Code For Chronic Nephritic Syndrome: Group Overview

N04-NEPHROTIC-SYNDROME

ICD-10-CM Code For Nephrotic Syndrome: Group Overview

N05-UNSPECIFIED-NEPHRITIC-SYNDROME

ICD-10-CM Code For Unspecified Nephritic Syndrome: Group Overview

N06-ISOLATED-PROTEINURIA-WITH-LESION

ICD-10-CM Code For Isolated Proteinuria With Specified Morphological Lesion: Group Overview

N07-HEREDITARY-NEPHROPATHY-NOT-ELSEWHERE-CLASSIFIED

ICD-10-CM Code For Hereditary Nephropathy Not Elsewhere Classified: Group Overview

N08-GLOMERULAR-DISORDERS-IN-DISEASES-CLASSIFIED-ELSEWHERE

ICD-10-CM Code For Glomerular Disorders In Diseases Classified Elsewhere: Group Overview

Frequently Asked Questions

References

1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.

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When to Use

ICD-10-CM Codes

13 rows

ICD-10-CM Code	Description
N00.0	Acute nephritic syndrome with minor glomerular abnormality
N00.1	Acute nephritic syndrome with focal and segmental glomerular lesions
N00.2	Acute nephritic syndrome with diffuse membranous glomerulonephritis
N00.3	Acute nephritic syndrome with diffuse mesangial proliferative glomerulonephritis
N00.4	Acute nephritic syndrome with diffuse endocapillary proliferative glomerulonephritis
N00.5	Acute nephritic syndrome with diffuse mesangiocapillary glomerulonephritis
N00.6	Acute nephritic syndrome with dense deposit disease
N00.7	Acute nephritic syndrome with diffuse crescentic glomerulonephritis
N00.8	Acute nephritic syndrome with other morphologic changes
N00.9	Acute nephritic syndrome with unspecified morphologic changes
N00.A	Acute nephritic syndrome with C3 glomerulonephritis
N00.B1	Acute nephritic syndrome with idiopathic immune membranoproliferative glomerulonephritis (IC-MPGN)
N00.B2	Acute nephritic syndrome with secondary immune complex membranoproliferative glomerulonephritis (IC-MPGN)

DRG Codes

5 rows

DRG Code	Description
698	Other Kidney and Urinary Tract Diagnoses with MCC
699	Other Kidney and Urinary Tract Diagnoses with CC
700	Other Kidney and Urinary Tract Diagnoses without CC/MCC
791	Prematurity with Major Problems
793	Full Term Neonate with Major Problems

Typical Clinical Scenarios

An adult presents to the emergency department with sudden onset hematuria, oliguria, edema, hypertension, and rising serum creatinine over 48 hours after a recent streptococcal throat infection. Urinalysis shows red blood cell casts and nephritic-range proteinuria; the clinical picture is consistent with an acute postinfectious glomerulonephritis causing acute nephritic syndrome, so a code from this group is assigned to reflect the acute glomerular inflammatory process. Typical codes: N00.0, N00.1
A middle-aged patient with known rapidly progressive glomerulonephritis develops days-to-weeks of worsening renal function, heavy proteinuria, and active urinary sediment; they are admitted for biopsy-proven crescentic glomerulonephritis requiring urgent immunosuppressive therapy. Because the presentation is an acute nephritic process with crescent formation and rapidly declining GFR, an acute nephritic syndrome code from this group is used to capture the glomerular disease acuity and subtype. Typical codes: N00.2, N00.3
An elderly patient with systemic lupus erythematosus is seen in clinic for new hypertension, edema, and microscopic hematuria on routine labs; renal biopsy confirms lupus nephritis with an acute nephritic component superimposed on chronic changes. In this comorbidity scenario where chronic autoimmune kidney disease has an acute nephritic exacerbation, a code from this group is assigned to indicate the acute nephritic involvement of the glomeruli alongside the underlying disorder. Typical codes: N00.4, N00.9

ICD-10-CM Code For Rapidly Progressive Nephritic Syndrome: Group Overview

N02-RECURRENT-AND-PERSISTENT-HEMATURIA

ICD-10-CM Code For Recurrent And Persistent Hematuria: Group Overview

N03-CHRONIC-NEPHRITIC-SYNDROME

ICD-10-CM Code For Chronic Nephritic Syndrome: Group Overview

N04-NEPHROTIC-SYNDROME

ICD-10-CM Code For Nephrotic Syndrome: Group Overview

N05-UNSPECIFIED-NEPHRITIC-SYNDROME

ICD-10-CM Code For Unspecified Nephritic Syndrome: Group Overview

N06-ISOLATED-PROTEINURIA-WITH-LESION

ICD-10-CM Code For Isolated Proteinuria With Specified Morphological Lesion: Group Overview

N07-HEREDITARY-NEPHROPATHY-NOT-ELSEWHERE-CLASSIFIED

ICD-10-CM Code For Hereditary Nephropathy Not Elsewhere Classified: Group Overview

N08-GLOMERULAR-DISORDERS-IN-DISEASES-CLASSIFIED-ELSEWHERE

ICD-10-CM Code For Glomerular Disorders In Diseases Classified Elsewhere: Group Overview

Frequently Asked Questions

References

1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.

Published by

Trek Health powers OpenPayer with a leading commercial payer intelligence platform, seamlessly converting fragmented payer data into actionable insights for provider organizations.

ICD-10-CM Code For Acute Nephritic Syndrome: Group Overview

Sign up for ICD-10-CM Code For Acute Nephritic Syndrome: Group Overview policy alerts

ICD-10-CM N00: Acute Nephritic Syndrome Overview

ICD-10-CM Code For Acute Nephritic Syndrome: Group Overview

Sign up for ICD-10-CM Code For Acute Nephritic Syndrome: Group Overview policy alerts

ICD-10-CM N00: Acute Nephritic Syndrome Overview

When to Use

ICD-10-CM Codes

DRG Codes

Typical Clinical Scenarios

Related Codes

References

When to Use

ICD-10-CM Codes

DRG Codes

Typical Clinical Scenarios

Related Codes

References

ICD-10-CM Code For Acute Nephritic Syndrome: Group Overview

Sign up for ICD-10-CM Code For Acute Nephritic Syndrome: Group Overview policy alerts

ICD-10-CM N00: Acute Nephritic Syndrome Overview

ICD-10-CM Code For Acute Nephritic Syndrome: Group Overview

Sign up for ICD-10-CM Code For Acute Nephritic Syndrome: Group Overview policy alerts

ICD-10-CM N00: Acute Nephritic Syndrome Overview

When to Use

ICD-10-CM Codes

DRG Codes

Typical Clinical Scenarios

Related Codes

Which ICD-10-CM codes identify specific morphologic patterns of acute nephritic syndrome?

What clinical features are associated with diagnoses in ICD-10-CM group `N00`?

How does accurate coding within the `N00` group affect claims and documentation?

Which DRGs are related to diagnoses in the acute nephritic syndrome `N00` group?

Are there specific subcodes for immune-mediated membranoproliferative forms in `N00`?

References

When to Use

ICD-10-CM Codes

DRG Codes

Typical Clinical Scenarios

Related Codes

Which ICD-10-CM codes identify specific morphologic patterns of acute nephritic syndrome?

What clinical features are associated with diagnoses in ICD-10-CM group `N00`?

How does accurate coding within the `N00` group affect claims and documentation?

Which DRGs are related to diagnoses in the acute nephritic syndrome `N00` group?

Are there specific subcodes for immune-mediated membranoproliferative forms in `N00`?

References