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    v1.0.30
    OpenPayerBilling CodesImmunization Administration for Vaccines/ToxoidsCPT cpt-90461-additional-live-attenuated-vaccine-administration-pediatrics
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    CPT 90461: Additional Live Attenuated Vaccine Administration, Pediatrics

    Medicare pays $9 on average nationally for this procedure.

    CPT code 90461 describes administration of an additional live attenuated vaccine (parenteral, oral, intranasal, intramuscular, or intravenous) given to a patient up to 18 years of age after the first vaccine; service type: vaccine administration / immunization service provided typically in ** outpatient clinic, pediatric office, public health clinic, or school-based immunization settings**.

    For related coverage guidance, see recent payer policy updates: Abortion Services, Prolonged Services for Labor Management, Prolonged Services for Labor Management.

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    Clinical & Coding Specifications

    Clinical Context

    A 12-year-old child presents to a pediatric primary care clinic for routine immunizations during a well-child visit. The clinician administers an initial live attenuated vaccine (for example, intranasal live attenuated influenza vaccine or oral rotavirus vaccine) and, per the immunization schedule or clinical indications, administers an additional live attenuated vaccine during the same visit for ongoing protection. The clinical workflow includes verification of patient identity and age (patient must be ≤18 years), review of immunization history and contraindications, obtaining informed assent/consent from the parent or guardian, preparation of the appropriate vaccine formulation (parenteral, oral, intranasal, intramuscular, or intravenous if applicable), administration, observation for immediate adverse reactions (typically 15–30 minutes), and documentation of vaccine product, lot number, site, route, date/time, and provider information. Billing is submitted using 90461 to report the administration of the additional live attenuated vaccine for a patient up to 18 years of age after the first vaccine was administered during the same encounter.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    90460Immunization administration through 18 years of age via any route of administration, with counseling by physician or other qualified health care professional; first or only component of each vaccine or toxoid administeredUse for the initial immunization administration when counseling is provided; 90461 is billed for the additional live attenuated vaccine given during the same visit.
    90471Immunization administration (includes percutaneous, intradermal, subcutaneous, or intramuscular injections); one vaccine (single or combination vaccine/toxoid)Use when a single parenteral vaccine is administered without counseling; for multiple injections, other related administration codes may apply.
    90472Each additional vaccine (single or combination vaccine/toxoid) administered to a patient through 18 years of age, per injectionUse when additional injectable vaccines are administered in the same visit (alternative reporting to 90461 depending on vaccine type and payer guidance).
    90732Pneumococcal conjugate vaccine, 13-valent, for intramuscular useExample of a vaccine product that may be administered in the same visit; product/procedure codes for vaccine supply are often billed separately.
    90734Hepatitis A vaccine, pediatric/adolescent dosage, intramuscularAnother vaccine product commonly administered in pediatric visits alongside live attenuated vaccines.

    Related Modifiers

    7 rows

    ModifierDescriptionWhen to Use
    25CPT modifier 25 indicates that on the same day as another procedure or service, the same physician or other qualified health care professional provided a significant, separately identifiable…- When to apply: Use modifier 25 only on an E/M code to indicate the same provider delivered a significant, separately identifiable E/M service on the same day as another procedure or service — i.e.,…
    59Modifier 59 indicates a distinct procedural service when two procedures that are not normally billed together are clinically and procedurally separate. The CPT definition (as reiterated by CMS)…- Use modifier -59 to report a distinct procedural service when documentation supports that the procedure reported is not normally billed together with another service on the same day because of a…
    76Modifier -76, Repeat Procedure or Service by Same Physician or Other Qualified Health Care Professional, is appended when the same provider performs an identical, medically necessary procedure or…- Use modifier -76 when the same physician or other qualified health care professional performs an identical procedure or service a second (or subsequent) time on the same date of service and the…
    77Modifier 77 indicates that a previously performed procedure or service was legitimately repeated by a different physician or other qualified health care professional. The AMA’s CPT definition…- Use modifier 77 when a basic procedure or service already performed is repeated by a different physician or other qualified health care professional (for example, a second provider independently…
    51Modifier –51 (Multiple Procedures) is used when the same provider performs multiple procedures in the same session to identify secondary, non‑exempt procedures and indicate payment reduction logic…- Use modifier -51 when the same provider performs multiple distinct procedures during the same patient encounter: report the highest‑valued procedure first (no modifier) and append -51 to…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    208000000X
    207Q00000X
    363A00000X
    207L00000X
    207SC0300X
    2278P1006X
    2084E0001X
    225X00000X

    Related Payer Policy Updates

    Specialty: Obstetrics/Gynecology1 / 3

    10 rows

    PolicyPayerEffective Date
    Abortion ServicesNew Mexico Health Care Authority2027-01-01
    Prolonged Services for Labor ManagementPremera Bluecross2027-01-01
    Prolonged Services for Labor ManagementPremera Bluecross2027-01-01
    Maternal Serum Testing for Prediction of Adverse Obstetric OutcomesPremera Bluecross2026-10-01
    Maternal Serum Testing for Prediction of Adverse Obstetric OutcomesPremera Bluecross2026-10-01
    Maternal Serum Testing for Prediction of Adverse Obstetric OutcomesBlue Cross Blue Shield - Massachusetts2026-10-01
    Cervical Cancer ScreeningOscar Health2026-10-01
    Prenatal Testing for Fetal AneuploidyOscar Health2026-10-01
    Diagnosis of VaginitisOscar Health2026-10-01
    Prenatal Screening (Nongenetic)Oscar Health2026-10-01

    Related Codes

    CPT-90460-SINGLE-LIVE-ATTENUATED-VACCINE-ADMINISTRATION-PEDIATRIC

    CPT 90460: Administration of Single Live Attenuated Vaccine, ≤18 Years

    CPT-90471-LIVE-ATTENUATED-VACCINE-ADMINISTRATION

    CPT 90471: Live Attenuated Vaccine Administration

    CPT-90472-ADDITIONAL-VACCINE-INJECTION

    CPT 90472: Vaccine Injection, Subsequent Dose

    CPT-90473-LIVE-ATTENUATED-INTRANASAL-OR-ORAL-VACCINE-ADMINISTRATION

    CPT 90473: Live Attenuated Intranasal or Oral Vaccine Administration

    CPT-90474-ADDITIONAL-LIVE-ATTENUATED-VACCINE-ORAL-INTRANASAL-ADMINISTRATION

    CPT 90474: Additional Live Attenuated Vaccine, Oral or Intranasal

    CPT-90480-COVID19-VACCINE-IM-INJECTION-FIRST-DOSE

    CPT 90480: COVID-19 Vaccine, First or Only Intramuscular Dose

    CPT-90481-MULTICOMPONENT-COVID19-VACCINE-INTRAMUSCULAR-ADD-ON

    CPT 90481: Multicomponent SARS–CoV–2 Vaccine Administration, Intramuscular

    CPT-90482-IMMUNIZATION-COUNSELING-NO-VACCINE-ADMINISTERED

    CPT 90482: Immunization Counseling, 3–10 Minutes

    CPT-90483-IMMUNIZATION-COUNSELING-NO-ADMINISTRATION-10-20-MIN

    CPT 90483: Immunization Counseling, 10–20 Minutes

    CPT-90484-IMMUNIZATION-COUNSELING-NO-VACCINE-ADMINISTERED

    CPT 90484: Immunization Counseling >20 Minutes

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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