CPT code 87591 represents an amplified nucleic acid probe test for Neisseria gonorrhoeae (GC), a molecular laboratory diagnostic used to detect the genetic material of the pathogen. This CPT code matters nationally because nucleic acid amplification tests are the clinical standard for gonorrhea diagnosis, guiding treatment decisions and public health reporting. Accurate lab coding affects claims processing, surveillance, and access to timely therapy.

Key payers in this national overview include Aetna, Blue Cross Blue Shield, Cigna Health, UnitedHealthcare, and Medicare. Readers will find concise benchmarks and practical context about clinical application, sites of service, and payer coverage considerations relevant to laboratory and billing staff. The summary addresses common reimbursement topics and coding context without state-specific detail.

This publication provides: a clear description of the test and its clinical role; typical sites where the service is performed; a checklist of what the code represents for claims and documentation; and guidance on where to find additional payer-specific coverage information. Data not available in the input is identified where applicable.