CPT code 87273 represents an immunofluorescent laboratory test to detect antigens of Herpes simplex virus type 2 (HSV-2), the virus commonly responsible for genital herpes. This test is a targeted diagnostic procedure used in clinical and hospital laboratories to identify viral proteins in patient specimens and support acute or suspected HSV-2 infection evaluation. Nationally, accurate laboratory identification of HSV-2 informs patient management, infection control, and public health surveillance.

Key payers covered in this analysis include Aetna, Blue Cross Blue Shield, Cigna Health, UnitedHealthcare, and Medicare. Readers will find a concise overview of clinical context for CPT code 87273, typical sites of service, and the kinds of benchmarks and payer coverage considerations commonly examined for laboratory virology codes. The publication also summarizes relevant billing modifiers and common administrative details where available.

The report is organized to provide: a clinical description and service use case; payer coverage scope and typical reimbursement considerations; and operational context for laboratories that perform immunofluorescent antigen detection for HSV-2. Data not available in the input is identified where applicable.