CPT 86833: HLA Class II Single-Antigen Solid-Phase Immunoassay

CPT code 86833 describes a laboratory solid-phase immunoassay performed on patient serum to detect specific antibodies to Class II human leukocyte antigens (HLA) using a high-definition single-antigen-per-bead method; the service is a specialized immunology serologic test typically performed in an ambulatory reference or hospital clinical laboratory setting to evaluate antibody specificity for transplant compatibility and immune monitoring.

For related coverage guidance, see recent payer policy updates: Biomarker Testing for Autoimmune Rheumatic Disease, Immune Cell Function Assay, Immunopharmacologic Monitoring of Therapeutic Serum Antibodies.