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CPT 82306: Vitamin D Level, Serum
CPT code 82306 designates laboratory measurement of vitamin D levels from a serum specimen, a widely used test for assessing vitamin D status and related metabolic health. Nationwide, vitamin D testing is clinically significant for evaluating deficiency, bone health, and certain endocrine or metabolic conditions; its frequency and coverage policies affect outpatient laboratory utilization and payer spending.
Key payers in this analysis include Aetna, Blue Cross Blue Shield (BCBS), Cigna Health, UnitedHealthcare, and Medicare. Readers will find a concise overview of clinical context for the test, common service settings, and related laboratory panels. The publication summarizes payer coverage patterns and benchmarking context where available, highlights coding relationships to other common lab tests such as calcium and comprehensive metabolic panels, and outlines operational considerations for billing and claim submission.
This summary provides a national-level reference for revenue cycle, clinical laboratory, and practice leadership seeking clear attribution of the code, typical sites of service, and the kinds of clinical and billing relationships to expect when 82306 is ordered.
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Billing Code Overview
CPT code 82306 reports measurement of vitamin D levels, typically performed on a serum specimen. The analyte measured is a steroid hormone commonly referred to as the sunshine vitamin, produced in part by hepatic processes and largely sourced from skin exposure to sunlight.
Service Type: Laboratory test — clinical chemistry analyte measurement
Typical Site of Service: Clinical laboratory or hospital outpatient laboratory
National Reimbursement Benchmarks
Commercial pricing for CPT 82306 centers around a BUCA average commercial rate of $56.5, with payer-specific medians and means that vary meaningfully. Blue Cross Blue Shield shows the highest dispersion between its 75th and 25th percentiles ($85.00 - $52.60 = $32.40), followed by Aetna ($46.00 - $22.90 = $23.10) and Cigna ($43.10 - $18.40 = $24.70). UnitedHealth Group displays the tightest interquartile spread at $29.60 - $13.30 = $16.30, indicating relatively more consistent commercial pricing.
Looking at central tendencies, Blue Cross Blue Shield’s mean ($74.1) sits well above the BUCA average, while UnitedHealth Group’s mean ($25.8) sits below it; Aetna ($39.6) and Cigna ($33.4) are closer to BUCA. Extreme values include Blue Cross Blue Shield’s high maximum of $429.1 and Aetna’s low minimum of $4.9, underlining pockets of outlier pricing even as interquartile ranges highlight where most negotiated rates cluster.