CPT 82306: Vitamin D (25-Hydroxy) Serum Quantification
Commercial payers pay $56 on average nationally for this procedure.
CPT code 82306 reports quantification of vitamin D (25-hydroxyvitamin D) concentration, typically measured on a serum specimen by a clinical laboratory; the service is a laboratory biochemical assay used to assess vitamin D status and guide evaluation of bone metabolism and related endocrine conditions, generally performed in an outpatient clinical laboratory or hospital laboratory setting.
For related coverage guidance, see recent payer policy updates: Salivary Hormone Testing, Parathyroid Hormone, Phosphorus, Calcium, and Magnesium Testing, Bone Turnover Markers Testing.
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National Reimbursement Benchmarks
Commercial pricing for CPT 82306 centers around a BUCA average commercial rate of $56.5, with payer-specific medians and means that vary meaningfully. Blue Cross Blue Shield shows the highest dispersion between its 75th and 25th percentiles ($85.00 - $52.60 = $32.40), followed by Aetna ($46.00 - $22.90 = $23.10) and Cigna ($43.10 - $18.40 = $24.70). UnitedHealth Group displays the tightest interquartile spread at $29.60 - $13.30 = $16.30, indicating relatively more consistent commercial pricing.
Looking at central tendencies, Blue Cross Blue Shield’s mean ($74.1) sits well above the BUCA average, while UnitedHealth Group’s mean ($25.8) sits below it; Aetna ($39.6) and Cigna ($33.4) are closer to BUCA. Extreme values include Blue Cross Blue Shield’s high maximum of $429.1 and Aetna’s low minimum of $4.9, underlining pockets of outlier pricing even as interquartile ranges highlight where most negotiated rates cluster.