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    OpenPayerBilling CodesDiagnostic Nuclear Medicine Procedures on the Genitourinary SystemCPT cpt-78740-voiding-cystourethrogram-ureteral-reflux-evaluation
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    CPT 78740: Voiding Cystourethrogram to Evaluate Ureteral Reflux

    Medicare pays $154 on average nationally for this procedure.

    CPT code 78740 describes a fluoroscopic voiding cystourethrogram (VCUG) procedure in which contrast is introduced into the bladder and imaging is captured during filling and voiding to evaluate for ureteral reflux and bladder/urethral anatomy; service type: diagnostic fluoroscopic contrast study, typical site of service: radiology suite or hospital outpatient imaging center.

    For related coverage guidance, see recent payer policy updates: Vafseo (vadadustat) for anemia in CKD on dialysis, Metabolic Disorders - Cysteamine (Oral) Products for Individual and Family Plans, Kerendia (finerenone) — Coverage Criteria.

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    Clinical & Coding Specifications

    Clinical Context

    A pediatric or adult patient presents with recurrent urinary tract infections, unexplained febrile episodes, hydronephrosis on ultrasound, or suspected vesicoureteral reflux. The patient is scheduled for a cystogram with retrograde contrast instillation to evaluate for ureteral reflux into one or both ureters and to document bladder anatomy and voiding dynamics. The procedure is typically performed in an outpatient radiology or pediatric radiology fluoroscopy suite, or in an ambulatory surgery center when sedation is required.

    Workflow:

    • Patient arrives with relevant history, prior imaging, and current urinalysis or urine culture results.

    • Informed consent is obtained; sedation is planned if the patient is uncooperative (common in young children).

    • A sterile catheter is inserted into the bladder; baseline fluoroscopic spot images may be obtained.

    • Contrast is instilled while fluoroscopic imaging captures filling of the bladder and any reflux into the ureters and collecting systems; voiding images may be obtained if indicated.

    • Images are archived and a radiologist documents findings including presence/grade of reflux, bladder contour, post-void residual, and any complications.

    • The patient is monitored briefly post-procedure and discharged with follow-up instructions and communication to the referring clinician.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    74240Radiologic examination, intestines; contrast meal and follow-through (Note: not typically related)Data not available in the input.
    51798Installation of temporary indwelling bladder catheter, simple; without imagingPerformed prior to contrast cystography when catheter placement is needed and billed separately if done as a distinct service
    74420Fluoroscopy, pelvic; with voiding cystourethrographyClosely related fluoroscopic exam to evaluate bladder and urethra during voiding; often performed as part of or instead of a cystogram to document reflux during voiding
    74450Voiding cystourethrogram, radiological supervision and interpretationReporting code for dynamic imaging of bladder and urethra during voiding; used in workflow when voiding images are required
    76770Ultrasound, scrotum and contents, real time with image documentation; unilateral or limitedOften used in parallel evaluation of genitourinary tract but not directly part of cystogram workflow

    Related Modifiers

    9 rows

    ModifierDescriptionWhen to Use
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    76Modifier -76, Repeat Procedure or Service by Same Physician or Other Qualified Health Care Professional, is appended when the same provider performs an identical, medically necessary procedure or…- Use modifier -76 when the same physician or other qualified health care professional performs an identical procedure or service a second (or subsequent) time on the same date of service and the…
    26Modifier 26 (Professional Component) identifies and bills only the professional portion of a split service — the physician’s interpretation, report, and medical judgment — when the technical…- Use CPT Modifier -26 when you are billing only the professional component (PC) of a split‑bill eligible service—i.e., you performed the physician interpretation, medical judgment and prepared a…
    59Modifier 59 indicates a distinct procedural service when two procedures that are not normally billed together are clinically and procedurally separate. The CPT definition (as reiterated by CMS)…- Use modifier -59 to report a distinct procedural service when documentation supports that the procedure reported is not normally billed together with another service on the same day because of a…
    78CPT modifier -78 indicates an unplanned, related return to the operating or procedure room by the same provider during the global postoperative period. It is appended when treatment for a…- Use modifier -78 when an unplanned, related complication during the original procedure’s global postoperative period requires the patient to return to a formal operating or procedure room and the…
    80CPT® Modifier 80 (Assistant Surgeon) is appended to a surgical CPT code when a physician (MD or DO) provides full, continuous assistance throughout the operative procedure. It is intended only for…- Use CPT Modifier -80 when a physician (MD or DO) serves as an assistant surgeon and provides full, continuous assistance throughout the entire operative procedure; append -80 to the surgical CPT…
    82Modifier 82 is appended to a surgical CPT code to indicate that an attending physician acted as an assistant because a qualified resident surgeon was unavailable. In teaching hospitals it documents…- When to use: Append modifier 82 in teaching-hospital settings to indicate a physician served as an assistant surgeon because a qualified resident surgeon was unavailable (includes situations where…

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    207R00000X
    363A00000X
    208800000X
    363L00000X
    322D00000X
    2081P0301X
    156FX1800X
    111NS0005X

    Related Payer Policy Updates

    Specialty: Nephrology1 / 3

    10 rows

    PolicyPayerEffective Date
    Vafseo (vadadustat) for anemia in CKD on dialysisCigna2026-08-15
    Metabolic Disorders - Cysteamine (Oral) Products for Individual and Family PlansCigna2026-08-15
    Kerendia (finerenone) — Coverage CriteriaBlue Cross Blue Shield - Iowa2026-08-05
    Voyxact (sibeprenlimab-szsl) — Prior authorization / medical necessity for primary IgA nephropathyColorado Rocky Mountain Health Plans2026-08-01
    Oxlumo (lumasiran) and Rivfloza (nedosiran) — Coverage Criteria (Ohio)Colorado Rocky Mountain Health Plans2026-08-01
    Korsuva (difelikefalin) — Medical Benefit Drug Coverage Criteria (Ohio)Colorado Rocky Mountain Health Plans2026-08-01
    Complement Inhibitors - EmpaveliCigna2026-08-01
    Tolvaptan (Jynarque)Cigna2026-08-01
    Nephrology - Filspari (sparsentan) coverageCigna2026-08-01
    Rivfloza (nedosiran) prior authorization for PH1UnitedHealthcare2026-08-01

    Related Codes

    CPT-78700-KIDNEY-SCAN-NUCLEAR-MEDICINE-RENAL-FUNCTION

    CPT 78700: Kidney Scan (Cortical and Functional Renal Scintigraphy)

    CPT-78701-KIDNEY-SCAN-NUCLEAR-MEDICINE-KIDNEY-IMAGING

    CPT 78701: Kidney Nuclear Scan (Cortical and Functional)

    CPT-78707-KIDNEY-SCAN-NUCLEAR-MEDICINE

    CPT 78707: Kidney Scan (Renal Nuclear Medicine)

    CPT-78708-KIDNEY-SCAN-NUCLEAR-MEDICINE-RENAL-IMAGING

    CPT 78708: Kidney Scan (Renal Scintigraphy)

    CPT-78709-KIDNEY-SCAN-RENAL-NUCLEAR-IMAGING

    CPT 78709: Renal Nuclear Medicine Scan

    CPT-78725-KIDNEY-SCAN-NUCLEAR-MEDICINE-RENAL-IMAGING

    CPT 78725: Kidney Scan, Cortical and Functional

    CPT-78730-URETERAL-REFLUX-AND-BLADDER-FUNCTION-RADIOISOTOPE-STUDY

    CPT 78730: Ureteral Reflux Study with Bladder Functional Evaluation

    CPT-78761-NUCLEAR-MEDICINE-TESTICULAR-IMAGING-RADIOPHARMACEUTICAL

    CPT 78761: Scrotal Nuclear Medicine Scintigraphy for Acute Testicular Pain

    CPT-78799-DIAGNOSTIC-NUCLEAR-MEDICINE-GENITOURINARY

    CPT 78799: Diagnostic Nuclear Medicine Procedure, Genitourinary

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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