CPT code 77074 defines a diagnostic radiographic series of specific bones used to assess skeletal conditions, including evaluation for metastatic disease. As a targeted imaging service, it supports clinical decision-making for oncology staging, orthopedic assessment, and follow-up of bone pathology. Nationally, this code matters because it informs payment for multi‑site skeletal imaging that differs from single‑site radiographs and has implications for care coordination between oncology, orthopedics, and radiology.

Key payers covered in this analysis include Aetna, Blue Cross Blue Shield, Cigna Health, UnitedHealthcare, and Medicare. Readers will find a concise review of reimbursement context and commonly observed billing modifiers, clinical scenarios where the series is used, and operational considerations for sites of service such as outpatient imaging centers and hospital radiology departments.

This publication provides benchmarks for typical use, summarizes relevant policy updates affecting radiology coding and coverage, and outlines the clinical context for ordering a skeletal radiographic series. Data not available in the input is noted where applicable.