CPT code 54111 covers surgical excision of penile plaque or abnormal fibrous tissue with closure using a skin graft up to five centimeters, a procedure used to treat Peyronie’s disease. Nationally, this code captures definitive surgical management for patients experiencing significant penile curvature, pain during erection, palpable shaft lumps, or penile shortening that are refractory to conservative therapy. Because Peyronie’s disease can significantly affect quality of life and sexual function, accurate coding for reconstructive procedures matters for clinical tracking, access to specialty surgical care, and payment policy.

Key payers included in this analysis are Aetna, Blue Cross Blue Shield, Cigna Health, UnitedHealthcare, and Medicare. The publication provides readers with clinical context for when the procedure is performed, typical sites of service (ambulatory surgery centers and hospital operating rooms), and the coding specifics clinicians and billing teams need to document this reconstructive surgery. Readers will find benchmarks and payer coverage summaries where available, discussion of documentation elements required to support medical necessity, and summaries of common billing considerations. Data not available in the input are noted where applicable.