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    OpenPayerBilling CodesEndoscopic Retrograde Cholangiopancreatography (ERCP) ProceduresCPT cpt-43270-egd-upper-gastrointestinal-endoscopy-with-ablation
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    CPT 43270: Esophagogastroduodenoscopy with Dilation and Lesion Ablation

    Medicare pays $836 on average nationally for this procedure.

    CPT code 43270 describes an esophagogastroduodenoscopy (EGD) performed with passage of guidewires, dilation of strictures as needed, and ablation (destruction) of one or more lesions using a flexible endoscope passed through the mouth; service type: upper endoscopic therapeutic procedure; typical site of service: endoscopy suite or hospital outpatient endoscopy unit.

    For related coverage guidance, see recent payer policy updates: Dental Anesthesia Services, Anesthesia Services for Interventional Pain Management Procedures in an Adult, General Anesthesia and Conscious Sedation Services.

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    Table of contents

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    Clinical & Coding Specifications

    Clinical Context

    A 62-year-old patient with progressive dysphagia and weight loss is referred to gastroenterology for diagnostic and therapeutic evaluation. The clinician schedules an esophagogastroduodenoscopy (EGD) with possible dilation and endoscopic ablation of mucosal lesions. On the day of service the patient arrives to an outpatient endoscopy center, is assessed by nursing, and consents for the procedure. Procedural sedation (monitored anesthesia care or conscious sedation) is provided per facility policy. A flexible upper endoscope is advanced through the mouth to inspect the esophagus, stomach, and duodenum. Narrowed segments are traversed with guidewires and dilated if necessary. Visualized lesions (for example Barrett mucosa with dysplasia or isolated nodular lesions) are treated with endoscopic ablation (e.g., radiofrequency ablation or cryoablation) or focal destruction as indicated. Biopsies or specimen retrieval may be performed during the same session. The patient is recovered in the post-anesthesia area and discharged with procedure instructions and follow-up arranged based on findings and pathology results.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    43239Upper gastrointestinal endoscopy including esophagus, stomach, and either the duodenum or jejunum, with biopsy, single or multiplePerformed when mucosal biopsies are taken during an EGD; may be reported when biopsy-only specimens are obtained.
    43249Upper gastrointestinal endoscopy with removal of tumor(s), polyp(s), or other lesion(s) by hot biopsy forceps or snare techniqueReported when lesions visualized during EGD are excised endoscopically rather than ablated.
    43264EGD; with endoscopic controlled radial expansion (CRE) balloon dilation of esophagus, each dilationReported when dilation of strictures is performed using balloon dilation techniques in the same or staged session.
    43273EGD with ablation of tumors, polyps, or other lesions; using cryotherapyRepresents cryoablation modality when used to ablate lesions identified during EGD.
    43280EGD with complex endoscopic procedures such as submucosal dissection or esophageal stent placementUsed for advanced therapeutic interventions that may follow diagnostic EGD findings.
    99152Anesthesia for procedures on the upper gastrointestinal tract; with patient in ASA I–II, monitored anesthesia care/conscious sedation (reporting depends on payer policy)Billed when monitored anesthesia care or general anesthesia is provided for the EGD session (anesthesia coding may vary by payer).

    Related Modifiers

    9 rows

    ModifierDescriptionWhen to Use
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    23Modifier -23 (Unusual Anesthesia) is used on anesthesia service CPT codes when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia…- Use modifier -23 only on anesthesia CPT codes (00100–01999) when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia because of…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    59Modifier 59 indicates a distinct procedural service when two procedures that are not normally billed together are clinically and procedurally separate. The CPT definition (as reiterated by CMS)…- Use modifier -59 to report a distinct procedural service when documentation supports that the procedure reported is not normally billed together with another service on the same day because of a…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
    76Modifier -76, Repeat Procedure or Service by Same Physician or Other Qualified Health Care Professional, is appended when the same provider performs an identical, medically necessary procedure or…- Use modifier -76 when the same physician or other qualified health care professional performs an identical procedure or service a second (or subsequent) time on the same date of service and the…
    78CPT modifier -78 indicates an unplanned, related return to the operating or procedure room by the same provider during the global postoperative period. It is appended when treatment for a…- Use modifier -78 when an unplanned, related complication during the original procedure’s global postoperative period requires the patient to return to a formal operating or procedure room and the…
    79Modifier 79 indicates a surgical procedure performed during the postoperative global period of a prior surgery that is unrelated to the original procedure. Per AMA/CPT and CMS guidance, it is…- Use modifier 79 when the same physician (or same‑specialty physician in the same group) performs a surgical procedure during the postoperative global period of a prior surgery and the new procedure…

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    207RH0000X
    207RC0000X
    207RN0300X
    363LA2200X
    163WC0400X
    221700000X
    2084P0015X
    261QC1800X

    Related ICD-10-CM Codes

    24 rows

    ICD-10-CM CodeDescription
    C15.9Malignant neoplasm of esophagus, unspecified
    C16.9Malignant neoplasm of stomach, unspecified
    K21.9Gastro-esophageal reflux disease without esophagitis
    K22.2Esophageal obstruction
    K22.3Perforation of esophagus
    K25.4Chronic or unspecified gastric ulcer with hemorrhage
    K25.9Gastric ulcer, unspecified as acute or chronic, without hemorrhage or perforation
    K26.9Duodenal ulcer, unspecified as acute or chronic, without hemorrhage or perforation
    K27.9Peptic ulcer, site unspecified, unspecified as acute or chronic, without hemorrhage or perforation
    K29.70Gastritis, unspecified, without bleeding

    Showing 1–10 of 24

    Related Payer Policy Updates

    Specialty: Anesthesiology1 / 3

    10 rows

    PolicyPayerEffective Date
    Dental Anesthesia ServicesProvidence Health Plan2026-10-01
    Anesthesia Services for Interventional Pain Management Procedures in an AdultCigna2026-09-15
    General Anesthesia and Conscious Sedation ServicesUnitedHealthcare2026-09-01
    Intravenous Anesthetics for the Treatment of Chronic Pain and Psychiatric or Substance Use DisordersPremera Bluecross2026-07-01
    Intravenous Anesthetics for the Treatment of Chronic Pain and Psychiatric or Substance Use DisordersPremera Bluecross2026-07-01
    Intravenous Anesthetics for the Treatment of Chronic Pain and Psychiatric or Substance Use DisordersPremera Bluecross2026-07-01
    Intravenous Anesthetics for the Treatment of Chronic Pain and Psychiatric or Substance Use DisordersPremera Bluecross2026-07-01
    Elective Inpatient Services (for Idaho Only)UnitedHealthcare2026-06-01
    Sites of Servicepriority health2026-06-01
    Coverage for Ambulatory Surgery Unit (ASU)/Outpatient Facility and Anesthesia for Dental Servicesuniverahealthcare2026-05-21

    Related Codes

    CPT-43260-DIAGNOSTIC-ERCP-UPPER-ENDOSCOPY-BILIARY-CONTRAST

    CPT 43260: Diagnostic Upper Endoscopy with Cholangiography and Brushing

    CPT-43261-ERCP-WITH-BIOPSY-DIAGNOSTIC-ENDOSCOPY-BILIARY-PANCREATIC-IMAGING

    CPT 43261: Upper Endoscopy with ERCP and Biopsy

    CPT-43262-ERCP-SPHINCTEROTOMY-PAPILLOTOMY

    CPT 43262: ERCP with Sphincterotomy/Papillotomy

    CPT-43263-ENDOSCOPIC-ERCP-WITH-SPHINCTER-OF-ODDI-MANOMETRY

    CPT 43263: Endoscopic Retrograde Cholangiopancreatography with Sphincter of Oddi Manometry

    CPT-43264-ERCP-ENDOSCOPY-DUCTAL-STONE-REMOVAL

    CPT 43264: ERCP with Diagnostic Imaging and Ductal Stone Removal

    CPT-43265-ERCP-THERAPEUTIC-PANCREATICOBILIARY-STONE-DESTRUCTION

    CPT 43265: ERCP with Stone Destruction and Radiologic Assessment of Biliary/Pancreatic Ducts

    CPT-43273-ERCP-VISUALIZATION-PANCREATIC-COMMON-BILE-DUCTS

    CPT 43273: ERCP Visualization of Pancreatic or Bile Ducts

    CPT-43274-ERCP-BILIARY-OR-PANCREATIC-DUCT-STENT-PLACEMENT

    CPT 43274: ERCP with Biliary or Pancreatic Duct Stent Placement

    CPT-43275-ERCP-ENDOSCOPIC-REMOVAL-BILIARY-PANCREATIC-STENT-FOREIGN-BODY

    CPT 43275: ERCP with Removal of Biliary/Pancreatic Foreign Body or Stent

    CPT-43276-ERCP-WITH-SINGLE-DUCT-STENT-REMOVAL-AND-EXCHANGE

    CPT 43276: ERCP with Single Duct Stent Removal and Exchange

    Showing 1–10 of 12

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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