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    v1.0.30
    OpenPayerBilling CodesEndoscopic Retrograde Cholangiopancreatography (ERCP) ProceduresCPT cpt-43264-ercp-endoscopy-ductal-stone-removal
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    CPT 43264: ERCP with Diagnostic Imaging and Ductal Stone Removal

    Medicare pays $323 on average nationally for this procedure.

    CPT code 43264 describes an endoscopic retrograde cholangiopancreatography (ERCP) diagnostic and therapeutic procedure combining upper endoscopy with retrograde injection of contrast into the biliary and pancreatic ducts to obtain fluoroscopic images of the bile ducts, gallbladder, and pancreas and to remove stones or debris; service type: endoscopic biliary/pancreatic diagnostic and therapeutic intervention; typical site of service: hospital outpatient department or ambulatory surgery center where endoscopy and fluoroscopy are performed.

    For related coverage guidance, see recent payer policy updates: Percutaneous Electrical Nerve Field Stimulation for Functional Abdominal Pain Disorders, Esophagogastroduodenoscopy (EGD) Coverage Policy, Radiofrequency Therapy for Fecal Incontinence.

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    Table of contents

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    Clinical & Coding Specifications

    Clinical Context

    A typical patient is a 58-year-old female presenting with right upper quadrant abdominal pain, jaundice, and abnormal liver function tests suggesting obstructive cholestasis. Noninvasive imaging (right upper quadrant ultrasound and/or MRCP) demonstrates a dilated common bile duct with suspected choledocholithiasis. The gastroenterology team schedules combined upper endoscopy with endoscopic retrograde cholangiopancreatography (ERCP) and stone extraction using biliary sphincterotomy and retrieval devices. The procedure is performed in an endoscopy suite or hybrid operating room under monitored anesthesia care or general anesthesia. The workflow includes pre-procedure consent and coagulation assessment, antibiotic prophylaxis when indicated, endoscopic cannulation of the ampulla, injection of contrast under fluoroscopy to visualize biliary and pancreatic ducts, removal of stones or debris from one or more ducts, placement of biliary stent if needed for drainage, post-procedure monitoring for pancreatitis, bleeding, perforation, or cholangitis, and documentation of findings and interventions in the procedural note. Typical payors include Aetna, Blue Cross Blue Shield, Cigna Health, UnitedHealthcare, BUCA, and Medicare.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    43235Upper gastrointestinal endoscopy including esophagus, stomach, and either the duodenum or jejunum; diagnostic, flexible, transoralMay be performed immediately prior to 43264 as the diagnostic upper endoscopic component or when diagnostic endoscopy alone is performed
    43267Endoscopic retrograde cholangiopancreatography, with endoscopic sphincterotomy, with or without dilation of the papilla; when performed with biliary stone extractionAlternative/add-on code used when sphincterotomy with stone extraction is the primary biliary therapeutic maneuver
    43268Endoscopic retrograde cholangiopancreatography with insertion of stent into bile or pancreatic ductPerformed during the same session if stent placement is required for drainage after stone extraction or ductal injury
    43246Endoscopic retrograde cholangiopancreatography, diagnostic, with or without collection of specimens by brushing or washingUsed when diagnostic ERCP without therapeutic intervention is performed
    43188Endoscopic removal of lesion(s) of esophagus, stomach or duodenum; polypectomy, hot or cold snareMay be performed during the same endoscopic session if mucosal lesions requiring removal are encountered

    Related Modifiers

    10 rows

    ModifierDescriptionWhen to Use
    26Modifier 26 (Professional Component) identifies and bills only the professional portion of a split service — the physician’s interpretation, report, and medical judgment — when the technical…- Use CPT Modifier -26 when you are billing only the professional component (PC) of a split‑bill eligible service—i.e., you performed the physician interpretation, medical judgment and prepared a…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    54Modifier ‑54 (“Surgical care only”) is appended to a CPT surgical procedure when the reporting surgeon performs the intraoperative (surgical) component but does not furnish the preoperative and/or…- Use modifier -54 when the reporting surgeon provided only the intraoperative (surgical) component of a procedure and preoperative and/or postoperative management has been or will be provided by…
    55Modifier –55 indicates the billing provider furnished only postoperative management for a procedure that has a global surgical period. According to AAPC, this modifier is appended to the same CPT…- Use modifier -55 when billing the same CPT surgical code that has a 10- or 90-day global period and you, as a provider other than the original surgeon, furnished ONLY postoperative management (no…
    59Modifier 59 indicates a distinct procedural service when two procedures that are not normally billed together are clinically and procedurally separate. The CPT definition (as reiterated by CMS)…- Use modifier -59 to report a distinct procedural service when documentation supports that the procedure reported is not normally billed together with another service on the same day because of a…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
    66Modifier 66 (Surgical Team) is used when three or more surgeons act as primary surgeons on a single, highly complex procedure. The AMA defines it for use when a surgical team — often composed of…- Use modifier 66 when three or more surgeons act as primary surgeons working collaboratively as a surgical team on a single, highly complex or difficult procedure (for example organ…
    73Modifier 73 indicates a facility-level outpatient hospital or ASC procedure that was discontinued after the patient was prepared and taken to the procedure/operating room but before any anesthesia…- When to use: Apply CPT modifier 73 on the FACILITY (outpatient hospital or ASC) claim when the patient has been fully prepared and physically taken into the procedure/operating room but the…
    91Modifier 91 — “Repeat Clinical Diagnostic Laboratory Test” — is appended when the exact same CPT laboratory test is performed more than once for the same patient on the same day because serial,…- Use modifier 91 when the exact same CPT laboratory test is performed more than once on the same patient on the same date because serial or repeated testing is medically necessary to monitor…

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    207K00000X
    208000000X
    3336C0003X
    261QM0801X
    2086S0102X
    152WP0200X
    363LC0200X
    133V00000X

    Related Payer Policy Updates

    Specialty: Gastroenterology1 / 2

    10 rows

    PolicyPayerEffective Date
    Percutaneous Electrical Nerve Field Stimulation for Functional Abdominal Pain Disordersbcbsvermont2026-12-01
    Esophagogastroduodenoscopy (EGD) Coverage Policyevicore2026-11-05
    Radiofrequency Therapy for Fecal IncontinenceCigna2026-10-15
    Magnetic Sphincter Augmentation for the Treatment of Gastroesophageal Reflux Disease (GERD)univerahealthcare2026-10-15
    High-Resolution Anoscopy (HRA)Premera Bluecross2026-10-01
    Gastroesophageal and Gastrointestinal (GI) Services and ProceduresColorado Rocky Mountain Health Plans2026-10-01
    Fecal Analysis in the Diagnosis of Intestinal Dysbiosis and Fecal Microbiota Transplant TestingOscar Health2026-10-01
    Serum Testing for Hepatic Fibrosis in the Evaluation and Monitoring of Chronic Liver DiseaseOscar Health2026-10-01
    Pancreatic Enzyme Testing for Acute PancreatitisOscar Health2026-10-01
    Helicobacter pylori TestingOscar Health2026-10-01

    Related Codes

    CPT-43260-DIAGNOSTIC-ERCP-UPPER-ENDOSCOPY-BILIARY-CONTRAST

    CPT 43260: Diagnostic Upper Endoscopy with Cholangiography and Brushing

    CPT-43261-ERCP-WITH-BIOPSY-DIAGNOSTIC-ENDOSCOPY-BILIARY-PANCREATIC-IMAGING

    CPT 43261: Upper Endoscopy with ERCP and Biopsy

    CPT-43262-ERCP-SPHINCTEROTOMY-PAPILLOTOMY

    CPT 43262: ERCP with Sphincterotomy/Papillotomy

    CPT-43263-ENDOSCOPIC-ERCP-WITH-SPHINCTER-OF-ODDI-MANOMETRY

    CPT 43263: Endoscopic Retrograde Cholangiopancreatography with Sphincter of Oddi Manometry

    CPT-43265-ERCP-THERAPEUTIC-PANCREATICOBILIARY-STONE-DESTRUCTION

    CPT 43265: ERCP with Stone Destruction and Radiologic Assessment of Biliary/Pancreatic Ducts

    CPT-43270-EGD-UPPER-GASTROINTESTINAL-ENDOSCOPY-WITH-ABLATION

    CPT 43270: Esophagogastroduodenoscopy with Dilation and Lesion Ablation

    CPT-43273-ERCP-VISUALIZATION-PANCREATIC-COMMON-BILE-DUCTS

    CPT 43273: ERCP Visualization of Pancreatic or Bile Ducts

    CPT-43274-ERCP-BILIARY-OR-PANCREATIC-DUCT-STENT-PLACEMENT

    CPT 43274: ERCP with Biliary or Pancreatic Duct Stent Placement

    CPT-43275-ERCP-ENDOSCOPIC-REMOVAL-BILIARY-PANCREATIC-STENT-FOREIGN-BODY

    CPT 43275: ERCP with Removal of Biliary/Pancreatic Foreign Body or Stent

    CPT-43276-ERCP-WITH-SINGLE-DUCT-STENT-REMOVAL-AND-EXCHANGE

    CPT 43276: ERCP with Single Duct Stent Removal and Exchange

    Showing 1–10 of 12

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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