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    v1.0.30
    OpenPayerBilling CodesEndoscopic Retrograde Cholangiopancreatography (ERCP) ProceduresCPT cpt-43265-ercp-therapeutic-pancreaticobiliary-stone-destruction
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    CPT 43265: ERCP with Stone Destruction and Radiologic Assessment of Biliary/Pancreatic Ducts

    Medicare pays $384 on average nationally for this procedure.

    CPT code 43265 describes endoscopic retrograde cholangiopancreatography (ERCP) with endoscopic inspection of the duodenum and the papilla of Vater followed by radiologic assessment of the pancreatic duct and biliary tree and performance of stone destruction by any method; the service is an endoscopic therapeutic procedure typically performed in an endoscopy suite or hospital outpatient setting and is classified as an advanced gastrointestinal endoscopic procedure.

    For related coverage guidance, see recent payer policy updates: Percutaneous Electrical Nerve Field Stimulation for Functional Abdominal Pain Disorders, Esophagogastroduodenoscopy (EGD) Coverage Policy, Radiofrequency Therapy for Fecal Incontinence.

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    Table of contents

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    Clinical & Coding Specifications

    Clinical Context

    A 58-year-old patient presents with right upper quadrant abdominal pain, jaundice, and abnormal liver function tests suggesting obstructive biliary disease. Prior imaging (abdominal ultrasound and CT) demonstrates dilatation of the intrahepatic and extrahepatic bile ducts and a suspected common bile duct stone. The gastroenterologist schedules an endoscopic retrograde cholangiopancreatography (ERCP, CPT 43265) for diagnostic cholangiography and definitive stone management.

    The clinical workflow includes pre-procedure evaluation (consent, coagulation status, NPO), intravenous sedation or monitored anesthesia care, endoscopic duodenal intubation to identify the major papilla, cannulation of the bile duct, radiologic contrast injection for ductal imaging, and stone destruction using mechanical or lithotripsy methods as needed. Post-procedure monitoring includes assessment for complications (pancreatitis, bleeding, infection, perforation) and disposition planning (recovery unit observation, hospital admission if indicated).

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    43264Endoscopic retrograde cholangiopancreatography, diagnostic, including sphincterotomy if performedDiagnostic ERCP closely related when no stone destruction is performed; may be used for initial diagnostic evaluation
    43266ERCP with cannulation of pancreatic duct, includes diagnostic radiologic evaluation and therapeutic interventionsUsed when pancreatic duct access or therapy is required in addition to biliary work
    43267ERCP with removal of biliary or pancreatic duct stones by balloon or basketAlternative or adjunct technique for stone extraction when fragmentation is not required
    43268ERCP with endoscopic placement of prosthetic biliary stentUsed when stent placement is performed for biliary decompression after stone removal or if obstruction persists
    47562Laparoscopic cholecystectomy with cholangiographyMay be performed before or after ERCP in the broader management of biliary stone disease

    Related Modifiers

    10 rows

    ModifierDescriptionWhen to Use
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    59Modifier 59 indicates a distinct procedural service when two procedures that are not normally billed together are clinically and procedurally separate. The CPT definition (as reiterated by CMS)…- Use modifier -59 to report a distinct procedural service when documentation supports that the procedure reported is not normally billed together with another service on the same day because of a…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
    73Modifier 73 indicates a facility-level outpatient hospital or ASC procedure that was discontinued after the patient was prepared and taken to the procedure/operating room but before any anesthesia…- When to use: Apply CPT modifier 73 on the FACILITY (outpatient hospital or ASC) claim when the patient has been fully prepared and physically taken into the procedure/operating room but the…
    78CPT modifier -78 indicates an unplanned, related return to the operating or procedure room by the same provider during the global postoperative period. It is appended when treatment for a…- Use modifier -78 when an unplanned, related complication during the original procedure’s global postoperative period requires the patient to return to a formal operating or procedure room and the…
    80CPT® Modifier 80 (Assistant Surgeon) is appended to a surgical CPT code when a physician (MD or DO) provides full, continuous assistance throughout the operative procedure. It is intended only for…- Use CPT Modifier -80 when a physician (MD or DO) serves as an assistant surgeon and provides full, continuous assistance throughout the entire operative procedure; append -80 to the surgical CPT…
    81Modifier -81 indicates a physician served as a minimal assistant surgeon for part—not all—of an operative procedure. Use when a physician’s assisting role is limited and does not represent full…- Use CPT modifier -81 when a physician acts as a minimum assistant surgeon who assists during only part (a limited portion) of an operative procedure; append -81 to the primary surgical CPT code to…
    82Modifier 82 is appended to a surgical CPT code to indicate that an attending physician acted as an assistant because a qualified resident surgeon was unavailable. In teaching hospitals it documents…- When to use: Append modifier 82 in teaching-hospital settings to indicate a physician served as an assistant surgeon because a qualified resident surgeon was unavailable (includes situations where…

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    208VP0000X
    208800000X
    207RH0000X
    2279P4000X
    367500000X
    333300000X
    103TH0004X
    122400000X

    Related ICD-10-CM Codes

    24 rows

    ICD-10-CM CodeDescription
    K80.00Calculus of gallbladder with acute cholecystitis without obstruction
    K80.01Calculus of gallbladder with acute cholecystitis with obstruction
    K80.10Calculus of gallbladder with chronic cholecystitis without obstruction
    K80.11Calculus of gallbladder with chronic cholecystitis with obstruction
    K80.20Calculus of gallbladder without cholecystitis without obstruction
    K80.21Calculus of gallbladder without cholecystitis with obstruction
    K80.30Calculus of bile duct with cholangitis, unspecified, without obstruction
    K80.31Calculus of bile duct with cholangitis, unspecified, with obstruction
    K80.40Calculus of bile duct with cholecystitis, unspecified, without obstruction
    K80.41Calculus of bile duct with cholecystitis, unspecified, with obstruction

    Showing 1–10 of 24

    Related Payer Policy Updates

    Specialty: Gastroenterology1 / 2

    10 rows

    PolicyPayerEffective Date
    Percutaneous Electrical Nerve Field Stimulation for Functional Abdominal Pain Disordersbcbsvermont2026-12-01
    Esophagogastroduodenoscopy (EGD) Coverage Policyevicore2026-11-05
    Radiofrequency Therapy for Fecal IncontinenceCigna2026-10-15
    Magnetic Sphincter Augmentation for the Treatment of Gastroesophageal Reflux Disease (GERD)univerahealthcare2026-10-15
    High-Resolution Anoscopy (HRA)Premera Bluecross2026-10-01
    Gastroesophageal and Gastrointestinal (GI) Services and ProceduresColorado Rocky Mountain Health Plans2026-10-01
    Fecal Analysis in the Diagnosis of Intestinal Dysbiosis and Fecal Microbiota Transplant TestingOscar Health2026-10-01
    Serum Testing for Hepatic Fibrosis in the Evaluation and Monitoring of Chronic Liver DiseaseOscar Health2026-10-01
    Pancreatic Enzyme Testing for Acute PancreatitisOscar Health2026-10-01
    Helicobacter pylori TestingOscar Health2026-10-01

    Related Codes

    CPT-43260-DIAGNOSTIC-ERCP-UPPER-ENDOSCOPY-BILIARY-CONTRAST

    CPT 43260: Diagnostic Upper Endoscopy with Cholangiography and Brushing

    CPT-43261-ERCP-WITH-BIOPSY-DIAGNOSTIC-ENDOSCOPY-BILIARY-PANCREATIC-IMAGING

    CPT 43261: Upper Endoscopy with ERCP and Biopsy

    CPT-43262-ERCP-SPHINCTEROTOMY-PAPILLOTOMY

    CPT 43262: ERCP with Sphincterotomy/Papillotomy

    CPT-43263-ENDOSCOPIC-ERCP-WITH-SPHINCTER-OF-ODDI-MANOMETRY

    CPT 43263: Endoscopic Retrograde Cholangiopancreatography with Sphincter of Oddi Manometry

    CPT-43264-ERCP-ENDOSCOPY-DUCTAL-STONE-REMOVAL

    CPT 43264: ERCP with Diagnostic Imaging and Ductal Stone Removal

    CPT-43270-EGD-UPPER-GASTROINTESTINAL-ENDOSCOPY-WITH-ABLATION

    CPT 43270: Esophagogastroduodenoscopy with Dilation and Lesion Ablation

    CPT-43273-ERCP-VISUALIZATION-PANCREATIC-COMMON-BILE-DUCTS

    CPT 43273: ERCP Visualization of Pancreatic or Bile Ducts

    CPT-43274-ERCP-BILIARY-OR-PANCREATIC-DUCT-STENT-PLACEMENT

    CPT 43274: ERCP with Biliary or Pancreatic Duct Stent Placement

    CPT-43275-ERCP-ENDOSCOPIC-REMOVAL-BILIARY-PANCREATIC-STENT-FOREIGN-BODY

    CPT 43275: ERCP with Removal of Biliary/Pancreatic Foreign Body or Stent

    CPT-43276-ERCP-WITH-SINGLE-DUCT-STENT-REMOVAL-AND-EXCHANGE

    CPT 43276: ERCP with Single Duct Stent Removal and Exchange

    Showing 1–10 of 12

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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