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    OpenPayerBilling CodesMalignant neoplasms of female genital organsICD-10-CM c54-malignant-neoplasm-of-corpus-uteri
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    ICD-10-CM Code For Malignant Neoplasm Of Corpus Uteri: Group Overview

    The International Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM) code group C54 includes malignant neoplasms arising in the corpus uteri, covering primary endometrial cancers and other tumors centered in the uterine body. These ICD-10-CM diagnosis codes are used to document primary uterine malignancy diagnoses, capture tumor site specificity, and reflect clinical extent such as local invasion or extension. Accurate coding within the ICD-10-CM C54 group supports proper claim adjudication, complete clinical documentation, and appropriate reimbursement.

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    ICD-10-CM C54: Malignant Neoplasm Of Corpus Uteri Overview

    The ICD-10-CM C54 code group represents malignant tumors originating in the body (corpus) of the uterus, primarily endometrial carcinomas and other malignant uterine neoplasms. These diagnoses target the female reproductive system and often involve assessment of tumor location, extent, and histology. Accurate coding matters for correct claim adjudication, clinical record completeness, and appropriate resource allocation.

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    When to Use

    Use a code from this group when a primary malignant neoplasm is documented as arising in the body of the uterus. Assign the most specific code reflecting documented tumor location, histology details if required, and any noted extension or invasion.

    ICD-10-CM Codes

    6 rows

    ICD-10-CM CodeDescription
    C54.0Malignant neoplasm of isthmus uteri
    C54.1Malignant neoplasm of endometrium
    C54.2Malignant neoplasm of myometrium
    C54.3Malignant neoplasm of fundus uteri
    C54.8Malignant neoplasm of overlapping sites of corpus uteri
    C54.9Malignant neoplasm of corpus uteri, unspecified

    DRG Codes

    9 rows

    DRG CodeDescription
    736Uterine and Adnexa Procedures for Ovarian or Adnexal Malignancy with MCC
    737Uterine and Adnexa Procedures for Ovarian or Adnexal Malignancy with CC
    738Uterine and Adnexa Procedures for Ovarian or Adnexal Malignancy without CC/MCC
    739Uterine and Adnexa Procedures for Non-Ovarian and Non-Adnexal Malignancy with MCC
    740Uterine and Adnexa Procedures for Non-Ovarian and Non-Adnexal Malignancy with CC
    741Uterine and Adnexa Procedures for Non-Ovarian and Non-Adnexal Malignancy without CC/MCC
    754Malignancy, Female Reproductive System with MCC
    755Malignancy, Female Reproductive System with CC
    756Malignancy, Female Reproductive System without CC/MCC

    Typical Clinical Scenarios

    • A 62-year-old postmenopausal woman presents with several months of painless vaginal bleeding and pelvic pressure; pelvic examination reveals an enlarged, irregular uterus and transvaginal ultrasound shows an endometrial mass. An endometrial biopsy confirms endometrioid adenocarcinoma confined to the corpus of the uterus, and the diagnosis code from this group is assigned to capture the primary malignant tumor. Typical codes: C54.1, C54.3
    • A 49-year-old premenopausal woman with abnormal uterine bleeding and pelvic pain undergoes hysterectomy after imaging suggests deep myometrial invasion; pathology demonstrates malignant neoplasm originating in the uterine fundus with extension into the myometrium. The code is used to document the malignant primary site and guide staging and treatment planning. Typical codes: C54.0, C54.2
    • A 70-year-old woman with known uterine cancer treated previously presents with new pelvic pain and evidence of recurrent tumor invading adjacent pelvic structures on imaging and biopsy; she is evaluated for palliative management of local progression and potential metastasis. A code from this group is assigned to indicate the site of recurrent or progressive malignancy as a comorbidity impacting care. Typical codes: C54.8, C54.9

    Related Codes

    C51-MALIGNANT-NEOPLASM-OF-VULVA

    ICD-10-CM Code For Malignant Neoplasm Of Vulva: Group Overview

    C52-MALIGNANT-NEOPLASM-OF-VAGINA

    ICD-10-CM Code For Malignant Neoplasm Of Vagina: Group Overview

    C53-MALIGNANT-NEOPLASM-OF-CERVIX-UTERI

    ICD-10-CM Code For Malignant Neoplasm Of Cervix Uteri: Group Overview

    C55-MALIGNANT-NEOPLASM-OF-UTERUS

    ICD-10-CM Code For Malignant Neoplasm Of Uterus Part Unspecified: Group Overview

    C56-MALIGNANT-NEOPLASM-OF-OVARY

    ICD-10-CM Code For Malignant Neoplasm Of Ovary: Group Overview

    C57-MALIGNANT-NEOPLASM-OTHER-FEMALE-GENITAL-ORGANS

    ICD-10-CM Code For Malignant Neoplasm Of Other And Unspecified Female Genital Organs: Group Overview

    C58-MALIGNANT-NEOPLASM-OF-PLACENTA

    ICD-10-CM Code For Malignant Neoplasm Of Placenta: Group Overview

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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