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    v1.0.28
    OpenPayerBilling CodesMalignant neoplasms of female genital organsICD-10-CM c53-malignant-neoplasm-of-cervix-uteri
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    ICD-10-CM Code For Malignant Neoplasm Of Cervix Uteri: Group Overview

    The International Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM) code group C53 includes malignant neoplasms of the cervix uteri, covering invasive cancers of the cervical canal and exocervix and specifying laterality and anatomic subsite when applicable. These ICD-10-CM diagnosis codes are used to document clinical encounters for cervical cancer, capturing disease extent, tumor location, and any complications or metastases relevant to patient management. Accurate coding within the ICD-10-CM C53 group supports proper claim adjudication, complete clinical documentation, and appropriate reimbursement.

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    ICD-10-CM C53: Malignant Neoplasm Of Cervix Uteri Overview

    The ICD-10-CM C53 group represents malignant tumors originating in the cervix uteri, affecting the lower portion of the uterus and adjacent tissues. These diagnoses target oncologic conditions of the female reproductive tract and guide documentation of tumor location and histologic behavior. Accurate coding matters for clinical records and supports appropriate reimbursement and public health tracking.

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    When to Use

    Use a code from this group when a documented diagnosis indicates malignant neoplasm of the cervix uteri confirmed by clinical, imaging, or histopathologic evaluation. Select the most specific code to reflect tumor subsite, extent, and any documented metastasis or recurrence.

    ICD-10-CM Codes

    4 rows

    ICD-10-CM CodeDescription
    C53.0Malignant neoplasm of endocervix
    C53.1Malignant neoplasm of exocervix
    C53.8Malignant neoplasm of overlapping sites of cervix uteri
    C53.9Malignant neoplasm of cervix uteri, unspecified

    DRG Codes

    9 rows

    DRG CodeDescription
    736Uterine and Adnexa Procedures for Ovarian or Adnexal Malignancy with MCC
    737Uterine and Adnexa Procedures for Ovarian or Adnexal Malignancy with CC
    738Uterine and Adnexa Procedures for Ovarian or Adnexal Malignancy without CC/MCC
    739Uterine and Adnexa Procedures for Non-Ovarian and Non-Adnexal Malignancy with MCC
    740Uterine and Adnexa Procedures for Non-Ovarian and Non-Adnexal Malignancy with CC
    741Uterine and Adnexa Procedures for Non-Ovarian and Non-Adnexal Malignancy without CC/MCC
    754Malignancy, Female Reproductive System with MCC
    755Malignancy, Female Reproductive System with CC
    756Malignancy, Female Reproductive System without CC/MCC

    Typical Clinical Scenarios

    • A 52-year-old woman presents to gynecologic oncology clinic with postmenopausal vaginal bleeding and pelvic pain. Pelvic exam reveals an exophytic cervical mass; biopsy confirms invasive squamous cell carcinoma arising in the cervix, and staging workup is initiated for definitive treatment planning. Typical codes: C53.1, C53.9
    • A 38-year-old woman with a history of high‑grade cervical intraepithelial neoplasia, previously treated with conization, now reports abnormal vaginal discharge and intermittent bleeding; colposcopy and directed biopsy identify an adenocarcinoma of the endocervical canal requiring surgical management. Typical codes: C53.0, C53.8
    • A 66-year-old woman is admitted through the emergency department with acute urinary retention and worsening renal function; imaging shows locally advanced cervical cancer invading adjacent pelvic structures with hydronephrosis as a complication. Typical codes: C53.9, C53.8

    Related Codes

    C51-MALIGNANT-NEOPLASM-OF-VULVA

    ICD-10-CM Code For Malignant Neoplasm Of Vulva: Group Overview

    C52-MALIGNANT-NEOPLASM-OF-VAGINA

    ICD-10-CM Code For Malignant Neoplasm Of Vagina: Group Overview

    C54-MALIGNANT-NEOPLASM-OF-CORPUS-UTERI

    ICD-10-CM Code For Malignant Neoplasm Of Corpus Uteri: Group Overview

    C55-MALIGNANT-NEOPLASM-OF-UTERUS

    ICD-10-CM Code For Malignant Neoplasm Of Uterus Part Unspecified: Group Overview

    C56-MALIGNANT-NEOPLASM-OF-OVARY

    ICD-10-CM Code For Malignant Neoplasm Of Ovary: Group Overview

    C57-MALIGNANT-NEOPLASM-OTHER-FEMALE-GENITAL-ORGANS

    ICD-10-CM Code For Malignant Neoplasm Of Other And Unspecified Female Genital Organs: Group Overview

    C58-MALIGNANT-NEOPLASM-OF-PLACENTA

    ICD-10-CM Code For Malignant Neoplasm Of Placenta: Group Overview

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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