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    v1.0.28
    OpenPayerBilling CodesMalignant neoplasms of lip, oral cavity and pharynxICD-10-CM c08-malignant-salivary-gland-neoplasms
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    ICD-10-CM Code For Malignant Neoplasm Of Other And Unspecified Major Salivary Glands: Group Overview

    The International Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM) code group C08 includes malignant neoplasms of major salivary glands other than the parotid and unspecified major salivary gland malignancies, covering cancers of the submandibular, sublingual, and other specified or unspecified major salivary glands. These ICD-10-CM diagnosis codes are used to document primary malignant tumors of major salivary glands, capturing site specificity, laterality when applicable, and clinical complexity relevant to oncologic management and staging. Accurate coding within the ICD-10-CM C08 group supports proper claim adjudication, complete clinical documentation, and appropriate reimbursement.

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    ICD-10-CM C08: Malignant Neoplasm Of Other And Unspecified Major Salivary Glands Overview

    This group represents malignant tumors arising in major salivary glands other than the parotid or those not otherwise specified, affecting the head and neck region and adjacent structures. These diagnoses target oncologic conditions of the submandibular, sublingual, and other major salivary glands. Accurate coding supports correct clinical records and is important for reimbursement and tracking of oncologic care.

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    When to Use

    Use a code from this group when a patient is diagnosed with a primary malignant neoplasm of a major salivary gland other than the parotid or when the major salivary gland malignancy is recorded as unspecified. Select the most specific code available to reflect the exact gland and laterality documented in the medical record.

    ICD-10-CM Codes

    3 rows

    ICD-10-CM CodeDescription
    C08.0Malignant neoplasm of submandibular gland
    C08.1Malignant neoplasm of sublingual gland
    C08.9Malignant neoplasm of major salivary gland, unspecified

    DRG Codes

    6 rows

    DRG CodeDescription
    011Tracheostomy for Face, Mouth and Neck Diagnoses or Laryngectomy with MCC
    012Tracheostomy for Face, Mouth and Neck Diagnoses or Laryngectomy with CC
    013Tracheostomy for Face, Mouth and Neck Diagnoses or Laryngectomy without CC/MCC
    146Ear, Nose, Mouth and Throat Malignancy with MCC
    147Ear, Nose, Mouth and Throat Malignancy with CC
    148Ear, Nose, Mouth and Throat Malignancy without CC/MCC

    Typical Clinical Scenarios

    • An elderly patient presents to the otolaryngology clinic with a several-month history of a firm, progressively enlarging, painless mass in the parotid region and new-onset facial nerve weakness localized to the affected side. Imaging (MRI/CT) shows a solid enhancing tumor of the major salivary gland, and core needle biopsy confirms malignant salivary gland neoplasm arising in the parotid gland; a primary malignant salivary gland code is assigned for the confirmed tumor. Typical codes: C08.0
    • A middle-aged adult with a history of prior radiation exposure to the head and neck develops a rapidly enlarging submandibular gland mass with pain, trismus, and palpable cervical lymphadenopathy; fine-needle aspiration and staging workup demonstrate an aggressive carcinoma originating in the submandibular salivary gland with regional nodal involvement. This clinical presentation of a primary malignancy of a major salivary gland requiring oncologic staging and treatment is coded accordingly. Typical codes: C08.1
    • An older patient with previously treated salivary gland malignancy returns for evaluation of a new, poorly characterized mass in a major salivary gland where biopsy is inconclusive or unavailable; the clinician documents a malignant neoplasm of a major salivary gland but does not specify the exact gland. In the setting of a confirmed malignant process without further site specificity documented, an unspecified major salivary gland malignancy code is used. Typical codes: C08.9

    Related Codes

    C00-MALIGNANT-NEOPLASM-OF-LIP

    ICD-10-CM Code For Malignant Neoplasm Of Lip: Group Overview

    C01-MALIGNANT-NEOPLASM-BASE-OF-TONGUE

    ICD-10-CM Code For Malignant Neoplasm Of Base Of Tongue: Group Overview

    C02-MALIGNANT-NEOPLASM-OF-TONGUE

    ICD-10-CM Code For Malignant Neoplasm Of Other And Unspecified Parts Of Tongue: Group Overview

    C03-MALIGNANT-NEOPLASM-OF-GUM

    ICD-10-CM Code For Malignant Neoplasm Of Gum: Group Overview

    C04-MALIGNANT-NEOPLASM-OF-FLOOR-OF-MOUTH

    ICD-10-CM Code For Malignant Neoplasm Of Floor Of Mouth: Group Overview

    C05-MALIGNANT-NEOPLASM-OF-PALATE

    ICD-10-CM Code For Malignant Neoplasm Of Palate: Group Overview

    C06-MALIGNANT-NEOPLASM-OF-MOUTH

    ICD-10-CM Code For Malignant Neoplasm Of Other And Unspecified Parts Of Mouth: Group Overview

    C07-MALIGNANT-NEOPLASM-OF-PAROTID-GLAND

    ICD-10-CM Code For Malignant Neoplasm Of Parotid Gland: Group Overview

    C09-MALIGNANT-NEOPLASM-OF-TONSIL

    ICD-10-CM Code For Malignant Neoplasm Of Tonsil: Group Overview

    C10-MALIGNANT-NEOPLASM-OF-OROPHARYNX

    ICD-10-CM Code For Malignant Neoplasm Of Oropharynx: Group Overview

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    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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