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    v1.0.28
    OpenPayerBilling CodesMalignant neoplasms of lip, oral cavity and pharynxICD-10-CM c06-malignant-neoplasm-of-mouth
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    ICD-10-CM Code For Malignant Neoplasm Of Other And Unspecified Parts Of Mouth: Group Overview

    The International Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM) code group C06 includes malignant neoplasms of other and unspecified parts of the mouth, covering cancers arising in intraoral sites such as the cheek, floor of mouth, and other unspecified oral locations. These ICD-10-CM diagnosis codes are used to document clinical encounters involving primary malignant tumors of the oral cavity, capturing site specificity and extent when available. Accurate coding within the ICD-10-CM C06 group supports proper claim adjudication, complete clinical documentation, and appropriate reimbursement.

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    ICD-10-CM C06: Malignant Neoplasm Of Other And Unspecified Parts Of Mouth Overview

    This group represents malignant tumors originating in parts of the oral cavity that are not specified elsewhere or are described as other parts of the mouth, including sites such as the cheek, floor of mouth, hard palate, and unspecified intraoral locations. It targets cancers of the oral cavity and associated structures within the head and neck region. Accurate coding matters for appropriate claim adjudication, clinical record completeness, and capturing disease burden for treatment planning and quality measurement.

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    When to Use

    Use a code from this group when a documented diagnosis indicates a primary malignant tumor of other or unspecified parts of the mouth and no more specific site code within the oral cavity applies. Assign the most specific code available based on clinician documentation of tumor location and laterality if recorded.

    ICD-10-CM Codes

    6 rows

    ICD-10-CM CodeDescription
    C06.0Malignant neoplasm of cheek mucosa
    C06.1Malignant neoplasm of vestibule of mouth
    C06.2Malignant neoplasm of retromolar area
    C06.80Malignant neoplasm of overlapping sites of unspecified parts of mouth
    C06.89Malignant neoplasm of overlapping sites of other parts of mouth
    C06.9Malignant neoplasm of mouth, unspecified

    DRG Codes

    6 rows

    DRG CodeDescription
    011Tracheostomy for Face, Mouth and Neck Diagnoses or Laryngectomy with MCC
    012Tracheostomy for Face, Mouth and Neck Diagnoses or Laryngectomy with CC
    013Tracheostomy for Face, Mouth and Neck Diagnoses or Laryngectomy without CC/MCC
    146Ear, Nose, Mouth and Throat Malignancy with MCC
    147Ear, Nose, Mouth and Throat Malignancy with CC
    148Ear, Nose, Mouth and Throat Malignancy without CC/MCC

    Typical Clinical Scenarios

    • An older adult with a history of heavy tobacco and alcohol use presents to the ENT clinic with a nonhealing ulcerative lesion on the lateral border of the tongue that has been present for several months, associated with progressive pain and difficulty swallowing. Physical exam and biopsy confirm invasive squamous cell carcinoma localized to the lateral tongue; staging workup shows a primary oral cavity malignancy without extension to adjacent structures. Typical codes: C06.2, C06.9
    • A middle-aged patient is seen urgently after noticing a rapidly enlarging, painful mass on the hard palate with surface irregularity and occasional bleeding; imaging and biopsy demonstrate a primary malignant neoplasm arising from the hard palate mucosa. Because the lesion originates in the palate (other specified parts of the mouth) and requires prompt oncologic management, a code from this group is assigned to document the specific oral subsite. Typical codes: C06.80, C06.89
    • A patient with recently diagnosed oral cavity cancer previously treated with partial glossectomy presents for follow-up with new localized recurrence manifesting as an indurated lesion at the prior surgical site and intermittent bleeding; biopsy confirms recurrent or persistent malignancy confined to unspecified parts of the mouth. A code from this group is used to report the malignant neoplasm of the oral site as a comorbidity impacting further treatment decisions. Typical codes: C06.9, C06.1

    Related Codes

    C00-MALIGNANT-NEOPLASM-OF-LIP

    ICD-10-CM Code For Malignant Neoplasm Of Lip: Group Overview

    C01-MALIGNANT-NEOPLASM-BASE-OF-TONGUE

    ICD-10-CM Code For Malignant Neoplasm Of Base Of Tongue: Group Overview

    C02-MALIGNANT-NEOPLASM-OF-TONGUE

    ICD-10-CM Code For Malignant Neoplasm Of Other And Unspecified Parts Of Tongue: Group Overview

    C03-MALIGNANT-NEOPLASM-OF-GUM

    ICD-10-CM Code For Malignant Neoplasm Of Gum: Group Overview

    C04-MALIGNANT-NEOPLASM-OF-FLOOR-OF-MOUTH

    ICD-10-CM Code For Malignant Neoplasm Of Floor Of Mouth: Group Overview

    C05-MALIGNANT-NEOPLASM-OF-PALATE

    ICD-10-CM Code For Malignant Neoplasm Of Palate: Group Overview

    C07-MALIGNANT-NEOPLASM-OF-PAROTID-GLAND

    ICD-10-CM Code For Malignant Neoplasm Of Parotid Gland: Group Overview

    C08-MALIGNANT-SALIVARY-GLAND-NEOPLASMS

    ICD-10-CM Code For Malignant Neoplasm Of Other And Unspecified Major Salivary Glands: Group Overview

    C09-MALIGNANT-NEOPLASM-OF-TONSIL

    ICD-10-CM Code For Malignant Neoplasm Of Tonsil: Group Overview

    C10-MALIGNANT-NEOPLASM-OF-OROPHARYNX

    ICD-10-CM Code For Malignant Neoplasm Of Oropharynx: Group Overview

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    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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