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    OpenPayerNPI Medicare & MedicaidSema4 Opco, Inc
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    Sema4 Opco, Inc — Billing Profile & Reimbursement Data

    NPI 1518415991 · Branford, CT · Clinical Medical Laboratory

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    Sema4 Opco, Inc is a clinical medical laboratory provider located in Branford, Connecticut. This profile covers 0 Medicare and 80 Medicaid CPT/HCPCS procedure codes, with claims volume, average reimbursement, and total revenue by code, benchmarked against other providers billing the same services.

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    Provider details (source: NPPES NPI Registry)

    FieldValue
    Entity TypeOrganization
    OrganizationSema4 Opco, Inc
    Address1 Commercial St
    CityBranford
    StateCT
    ZIP06405
    TaxonomyClinical Medical Laboratory
    NPI EnumeratedSeptember 14, 2016

    Lifetime revenue by payer source (source: CMS Medicare & Medicaid claims data)

    Payer SourceTotal Paid
    Medicaid$10.8M
    Medicare$0

    Medicaid: Total Revenue Breakdown by CPT/HCPCS Code

    Medicaid revenue breakdown by year and by CPT/HCPCS procedure code, including monthly billing trends and the top codes driving revenue.

    View: By Year1 / 3

    Medicaid: Complete Services Breakdown

    Every CPT/HCPCS code this provider has billed to Medicaid, with claims volume, average payment, and total revenue.

    80 rows

    CPT/HCPCS CodeDescriptionClaimsAvg PaidRevenue
    81420The lab analyst performs a genomic sequence analysis panel to evaluate circulating cell free fetal DNA in maternal blood for genetic sequences of at least the genes on chromosomes 13, 18, and 21,…9,410$290$2.8M
    81220The lab analyst performs the technical lab test to detect the presence of changes in the gene for cystic fibrosis transmembrane conductance regulator, also known as CFTR. The test evaluates the CFTR…11,680$180$2.1M
    81408The lab analyst performs the technical lab test to complete one of the specific genetic analyses listed in this Tier 2, Level 9 molecular pathology code.10,770$100$1.1M
    81407The lab analyst performs the technical lab test to complete one of the specific genetic analyses listed in this Tier 2, Level 8 molecular pathology code.9,700$50$446.4K
    81329The lab analyst performs the technical lab test to detect deletions in the survival of motor neuron 1 (SMN1), telomeric, gene and may also analyze the survival of motor neuron 2 (SMN2), centromeric,…9,550$40$353.2K
    81406The lab analyst performs the technical lab test to complete one of the specific genetic analyses listed in this Tier 2, Level 7 molecular pathology code.11,610$30$348.2K
    81422The lab analyst performs a genomic sequence analysis panel to evaluate circulating cell–free fetal DNA in maternal blood for chromosomal microdeletion(s) associated with conditions such as DiGeorge…2,900$110$324.4K
    81162The lab analyst performs the technical lab test to analyze the entire gene sequence for the BRCA1, DNA repair–associated gene, also called BRCA1; and BRCA2, DNA repair–associated gene, also called…900$260$235.7K
    81404The lab analyst performs the technical lab tests to complete one of the specific genetic analyses listed in this Tier 2, Level 5 molecular pathology code.11,350$20$215.7K
    81405The lab analyst performs the technical lab tests to complete one of the specific genetic analyses listed in this Tier 2, Level 6 molecular pathology code.11,100$20$210.8K

    Showing 1–10 of 80

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    Medicaid: Competitive Analysis & Benchmarks

    How this provider's Medicaid billing volume and revenue compare to other Connecticut providers billing the same CPT/HCPCS codes.

    Full comparison — all codes billed, vs. Connecticut median

    80 rows

    CPT/HCPCS CodeDescriptionRankProvider CountMedian ClaimsAvg PaidAverage Revenue
    81420The lab analyst performs a genomic sequence analysis panel to evaluate circulating cell free fetal DNA in maternal blood for genetic sequences of at least the genes on chromosomes 13, 18, and 21,…2104,900$390$2.2M
    81479Use 81479 to report a molecular pathology procedure that does not have a specific code.310830$850$620.4K
    U00042019-ncov coronavirus, sars-cov-2/2019-ncov (covid-19), any technique, multiple types or subtypes (includes all targets), non-cdc, making use of high throughput technologies as described by…3305,480$60$581.1K
    81408The lab analyst performs the technical lab test to complete one of the specific genetic analyses listed in this Tier 2, Level 9 molecular pathology code.110230$100$378.4K
    81220The lab analyst performs the technical lab test to detect the presence of changes in the gene for cystic fibrosis transmembrane conductance regulator, also known as CFTR. The test evaluates the CFTR…110620$200$374.6K
    U0005Infectious agent detection by nucleic acid (dna or rna); severe acute respiratory syndrome coronavirus 2 (sars-cov-2) (coronavirus disease [covid-19]), amplified probe technique, cdc or non-cdc,…7504,960$20$273.9K
    81162The lab analyst performs the technical lab test to analyze the entire gene sequence for the BRCA1, DNA repair–associated gene, also called BRCA1; and BRCA2, DNA repair–associated gene, also called…110900$260$236.1K
    81251The lab analyst performs the technical lab test to detect the presence of specific changes in the gene for glucosidase, beta, acid, also known as GBA.1109,250$20$175.3K
    83080The lab analyst measures the amount of the beta–hexosaminidase A or B that is present, typically in a serum specimen. These two enzymes are deficient in conditions such as Tay–Sachs disease or…1109,750$20$167.1K
    81422The lab analyst performs a genomic sequence analysis panel to evaluate circulating cell–free fetal DNA in maternal blood for chromosomal microdeletion(s) associated with conditions such as DiGeorge…1101,470$110$162.8K

    Showing 1–10 of 80

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    Nearby Providers

    Other providers in the same ZIP code as Sema4 Opco, Inc, ranked by combined Medicare and Medicaid revenue.

    ProviderStateTaxonomyMedicare RevenueMedicaid Revenue
    Hhc Physician Services, PLLCCTInternal Medicine Physician$0$7.7M
    Physicians Alliance Of Connecticut, LLCCTInternal Medicine Physician$0$6.3M
    Genco Lab LLCCTClinical Medical Laboratory$648.4K$2.6M
    Branford Pediatrics & Allergy, P.C.CTAllergy Physician$0$3.1M
    Town Of BranfordCTLand Ambulance$542.1K$1.7M
    Prime Dental LLCCTGeneral Practice Dentistry$0$1.7M
    Town Of BranfordCTMental Health Clinic/Center (Including Community Mental Health Center)$0$1.7M
    Back To Health Of Branford, LLCCTInternal Medicine Physician$0$1.6M
    New Horizon Healthcare, LLCCTPhysician Assistant$0$1.4M
    Stony Creek Urgent Care Center, LLCCTGeneral Practice Physician$0$1.2M

    Frequently Asked Questions

    References

    1. 1.Medicare Physician & Other Practitioner by Provider and Service. CMS.gov.Provider-level Medicare Part B utilization and payment data.
    2. 2.NPPES NPI Registry. CMS.gov.National Provider Identifier registry used for provider enumeration and taxonomy metadata.

    Trek Health ingests and normalizes Transparency in Coverage data and payer policy updates to give provider organizations a clear view of how commercial reimbursement behaves across markets, payers, and services. Our platform transforms raw payer disclosures into structured intelligence that supports contract evaluation, payer negotiations, and service line strategy. By combining market benchmarks with ongoing policy visibility, Trek helps teams identify variability, risk, and opportunity in commercial reimbursement. The result is faster insight, stronger negotiating positions, and more informed financial decisions.

    Medicaid Revenue by Year vs. Connecticut Providers
    3 of 5 years billed far more than typical (above p95)
    p5–p95 (all providers)p25–p75MedianThis providerOutlier
    Claims Volume vs. Connecticut Distribution
    Sema4 Opco, Inc — 15 of 25 codes billed far more than typical (above p95)
    p5–p95 (all providers)p25–p75MedianThis providerOutlier
    Rank Distribution — Connecticut