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    OpenPayerNPI Medicare & MedicaidEsoterix Genetic Laboratories, LLC
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    Esoterix Genetic Laboratories, LLC — Billing Profile & Reimbursement Data

    NPI 1124536107 · Shelton, CT · Clinical Medical Laboratory

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    Esoterix Genetic Laboratories, LLC is a clinical medical laboratory provider located in Shelton, Connecticut. This profile covers 36 Medicare and 35 Medicaid CPT/HCPCS procedure codes, with claims volume, average reimbursement, and total revenue by code, benchmarked against other providers billing the same services.

    Provider details (source: NPPES NPI Registry)

    FieldValue
    Entity TypeOrganization
    OrganizationEsoterix Genetic Laboratories, LLC
    Address3 Forest Pkwy
    CityShelton
    StateCT
    ZIP06484
    TaxonomyClinical Medical Laboratory
    NPI EnumeratedJanuary 12, 2018

    Lifetime revenue by payer source (source: CMS Medicare & Medicaid claims data)

    Payer SourceTotal Paid
    Medicaid$3.2M
    Medicare$2.2M

    Key Findings

    ESOTERIX GENETIC LABORATORIES, LLC operates primarily as a diagnostic clinical laboratory focused on flow cytometry, cytogenetics and targeted genomic panels; its top billed services include flow cytometry add-on and core markers (88185, 88184, 88189), multiple FISH/karyotype cytogenetics codes (88275, 88271, 88264) and targeted sequencing panels (81450, 81455, 81206). The mix of high-volume immunophenotyping and cytogenetic codes alongside mid-volume molecular panels indicates a lab that services both routine hematopathology workflows and higher-complexity genetic testing vectors used in oncology and inherited-disease workups.

    Medicare revenue is concentrated: the top three Medicare codes account for 41.9% of this provider's total Medicare revenue. Notably, 88185 alone generates $556.4K (26.3% of Medicare revenue) and ranks #15 of 618 providers nationally (98th percentile, described as notably above typical national volume); 88275 contributes $170.1K (8.0%) and ranks #4 of 72 (96th percentile), while 81450 adds $158.5K (7.5%) and ranks #15 of 48 (70th percentile).

    Medicaid billing is even more concentrated: the top three Medicaid codes account for 56.9% of this provider's total Medicaid revenue. In Medicaid, 88185 is the dominant single driver with $1.1M (35.7% of Medicaid revenue) and ranks #2 of 10 in-state (89th percentile), followed by 81220 at $362.5K (11.4%) rank #3 of 9 (75th percentile) and U0003 at $307K (9.7%) rank #21 of 46 (56th percentile).

    The provider’s payer mix skews toward Medicaid in scale: reported Medicaid revenue is $3.2M compared with $2.2M in Medicare, so Medicaid represents the larger single payer relationship while Medicare remains a meaningful revenue source. This dual-payer footprint suggests the lab serves both Medicaid-heavy clinical pathways (including newborn/CFTR and state public testing programs) and Medicare oncology/hematology workflows.

    ESOTERIX is a competitive volume player on several laboratory-specific services at national and state levels. For Medicare, multiple codes show upper-percentile national rankings—88185 (98th), 88341 (99th), and 88271 (96th)—supporting characterization as a high-volume national performer in flow cytometry, immunohistochemistry, and cytogenetics; in-state Medicaid ranks include #1 or top positions for several codes (88360 #1 of 15, 88275 #1 of 2, 81207 #1 of 3, 81270 #1 of 3), indicating leadership or unique offerings within Connecticut for selected tests.

    Some service lines appear unique or relatively exclusive in-state: 81450 for a 5–50 gene hematolymphoid panel is reported in Medicaid as $23.9K and ranks #1 of 1 providers in-state (0th percentile; no state peer volume comparison available), implying ESOTERIX may be the only in-state Medicaid reporter for that panel. That exclusivity, combined with high-volume cytometry and cytogenetics, suggests the lab captures specialized referrals and niche genetic testing demand locally.

    The lab’s Medicaid portfolio includes a substantial SARS‑CoV‑2 testing footprint: U0003 shows 5K claims and $307K in Medicaid revenue (9.7% of Medicaid revenue), and U0005 also appears ($33.3K, 1.1%). These volumes indicate the provider supported high-throughput COVID PCR testing for Medicaid populations in the measurement period alongside its oncology/hematology services.

    ESOTERIX’s billing tenure is relatively recent but established: NPI enumerated 2018-01-12 (~8 years ago). Achieving $2.2M in Medicare and $3.2M in Medicaid over this span, with multiple top-percentile ranks, suggests rapid scale-up in both routine hematopathology testing and higher-complexity genetic diagnostics since enumeration.

    Medicare: Total Revenue Breakdown by CPT/HCPCS Code

    Medicare revenue breakdown by CPT/HCPCS procedure code.

    View: Bar Chart1 / 2

    Medicare: Complete Services Breakdown

    The CPT/HCPCS codes generating the most Medicare revenue for this provider.

    36 rows

    CPT/HCPCS CodeDescriptionClaimsAvg PaidRevenue
    88185The lab analyst performs the technical component of a flow cytometry procedure using cell surface, cytoplasmic, or nuclear markers to characterize cells and aid clinicians in diagnosing patients with…26,490$20$556.4K
    88275The analyst performs a molecular cytogenetic test using interphase in situ hybridization and analyzes 100 to 300 cells. Interphase refers to a period of time when a cell is not dividing and…3,470$50$170.1K
    81450The lab analyst performs a genomic sequence analysis panel to evaluate the patient specimen, such as blood or bone marrow, for DNA and possibly RNA alterations in five to 50 genes known to impact…210$740$158.5K
    81455The lab analyst performs a genomic sequence analysis panel to evaluate the patient specimen, such as tumor tissue or bone marrow, for DNA and possibly RNA alterations in 51 or more genes known to…50$2,860$145.9K
    88341The lab analyst applies an additional single antibody stain on a slide or slides prepared from the same patient specimen as the initial antibody stain, such as tumor tissue. Then a qualified…2,640$50$124.2K
    88271The analyst performs a molecular cytogenetic test using a DNA probe method, such as FISH, fluorescence in situ hybridization, to test cells for genetic abnormalities.5,410$20$113.7K
    88237The lab analyst performs a procedure to grow a culture of cells from bone marrow or blood in a neoplastic disorder.670$140$94.2K
    81206The lab analyst performs the technical lab test to evaluate the major breakpoint gene sequence BCR/ALB1 that occurs on chromosome 22 due to translocation, which involves breakage and reforming of an…540$160$87.4K
    81207The lab analyst performs the technical lab test to evaluate the minor breakpoint gene sequence BCR/ALB1 that occurs on chromosome 22 due to translocation, which involves breakage and reforming of an…550$140$77.4K
    88264The analyst performs a chromosome analysis and analyzes 20 to 25 cells. The analysis includes counting the number of chromosomes in each cell and preparing a karyotype for each cell examined.540$140$76.2K

    Showing 1–10 of 36

    Medicare: Competitive Analysis & Benchmarks

    How this provider's Medicare billing volume and revenue compare to other providers nationally and within its state, across 36 CPT/HCPCS codes.

    View: State1 / 2

    Full comparison — all codes billed, vs. state median

    36 rows

    CPT/HCPCS CodeRankProvider CountMedian ClaimsAvg PaidAverage Revenue
    8818531032,650$20$642.3K
    8837721030$300$134.4K
    8145511050$2,860$131.6K
    882751101,910$50$106.1K
    81450110130$740$96K
    882711104,250$20$82.1K
    881843101,290$60$81.1K
    88237110460$140$64K
    88264110460$140$55.3K
    81207110330$140$46.7K

    Showing 1–10 of 36

    Medicaid: Total Revenue Breakdown by CPT/HCPCS Code

    Medicaid revenue breakdown by year and by CPT/HCPCS procedure code, including monthly billing trends and the top codes driving revenue.

    View: By Year1 / 3

    Medicaid: Complete Services Breakdown

    Every CPT/HCPCS code this provider has billed to Medicaid, with claims volume, average payment, and total revenue.

    35 rows

    CPT/HCPCS CodeDescriptionClaimsAvg PaidRevenue
    88185The lab analyst performs the technical component of a flow cytometry procedure using cell surface, cytoplasmic, or nuclear markers to characterize cells and aid clinicians in diagnosing patients with…6,220$180$1.1M
    81220The lab analyst performs the technical lab test to detect the presence of changes in the gene for cystic fibrosis transmembrane conductance regulator, also known as CFTR. The test evaluates the CFTR…1,150$320$362.5K
    U0003Infectious agent detection by nucleic acid (dna or rna); severe acute respiratory syndrome coronavirus 2 (sars-cov-2) (coronavirus disease [covid-19]), amplified probe technique, making use of high…5,030$60$307K
    88341The lab analyst applies an additional single antibody stain on a slide or slides prepared from the same patient specimen as the initial antibody stain, such as tumor tissue. Then a qualified…4,060$60$251.7K
    88189The clinician, typically a pathologist, interprets flow cytometry results of 16 or more markers.3,890$30$116.7K
    81329The lab analyst performs the technical lab test to detect deletions in the survival of motor neuron 1 (SMN1), telomeric, gene and may also analyze the survival of motor neuron 2 (SMN2), centromeric,…1,440$80$110.6K
    88184The lab analyst performs the technical component of a flow cytometry procedure using a cell surface, cytoplasmic, or nuclear marker to characterize cells and aid clinicians in diagnosing patients…6,210$20$105.6K
    88342The lab analyst applies an initial single antibody stain on a slide or slides prepared from a single patient specimen, such as tumor tissue. Then a qualified provider, typically a pathologist,…6,280$10$87.9K
    88360The lab analyst applies a single antibody stain on a slide or slides prepared from a single patient specimen, such as tumor tissue. Then a qualified provider, typically a pathologist, evaluates the…3,250$30$84.4K
    88275The analyst performs a molecular cytogenetic test using interphase in situ hybridization and analyzes 100 to 300 cells. Interphase refers to a period of time when a cell is not dividing and…2,200$40$83.6K

    Showing 1–10 of 35

    Medicaid: Competitive Analysis & Benchmarks

    How this provider's Medicaid billing volume and revenue compare to other Connecticut providers billing the same CPT/HCPCS codes.

    Full comparison — all codes billed, vs. Connecticut median

    35 rows

    CPT/HCPCS CodeDescriptionRankProvider CountMedian ClaimsAvg PaidAverage Revenue
    U0003Infectious agent detection by nucleic acid (dna or rna); severe acute respiratory syndrome coronavirus 2 (sars-cov-2) (coronavirus disease [covid-19]), amplified probe technique, making use of high…21503,340$60$1M
    88305The physician, typically a pathologist, performs a level IV examination of a surgical pathology specimen. The examination includes accessioning the specimen into the lab, which involves formally…62903,980$40$424.8K
    81220The lab analyst performs the technical lab test to detect the presence of changes in the gene for cystic fibrosis transmembrane conductance regulator, also known as CFTR. The test evaluates the CFTR…310620$200$374.6K
    U0005Infectious agent detection by nucleic acid (dna or rna); severe acute respiratory syndrome coronavirus 2 (sars-cov-2) (coronavirus disease [covid-19]), amplified probe technique, cdc or non-cdc,…28504,960$20$273.9K
    88184The lab analyst performs the technical component of a flow cytometry procedure using a cell surface, cytoplasmic, or nuclear marker to characterize cells and aid clinicians in diagnosing patients…210650$80$188.6K
    88185The lab analyst performs the technical component of a flow cytometry procedure using cell surface, cytoplasmic, or nuclear markers to characterize cells and aid clinicians in diagnosing patients with…210630$60$132.7K
    88271The analyst performs a molecular cytogenetic test using a DNA probe method, such as FISH, fluorescence in situ hybridization, to test cells for genetic abnormalities.2102,390$60$100.2K
    81329The lab analyst performs the technical lab test to detect deletions in the survival of motor neuron 1 (SMN1), telomeric, gene and may also analyze the survival of motor neuron 2 (SMN2), centromeric,…210670$40$100K
    88313The lab analyst performs the technical lab steps to stain a specimen for Group II identification, for example an iron stain or trichrome stain. A qualified provider, typically a pathologist,…21401,210$30$99.6K
    88275The analyst performs a molecular cytogenetic test using interphase in situ hybridization and analyzes 100 to 300 cells. Interphase refers to a period of time when a cell is not dividing and…1102,140$40$89.2K

    Showing 1–10 of 35

    Related Providers

    Other providers that share a Tax Identification Number (TIN) with Esoterix Genetic Laboratories, LLC, ranked by combined Medicare and Medicaid revenue.

    ProviderStateTaxonomyMedicare RevenueMedicaid Revenue
    Laboratory Corporation Of America HoldingsNCClinical Medical Laboratory$214.6M$1.4B
    Laboratory Corporation Of America HoldingsNJClinical Medical Laboratory$143.3M$717.5M
    Natera, Inc.CAClinical Medical Laboratory$133.1M$641.5M
    Unilab CorporationCAClinical Medical Laboratory$94M$668.5M
    Quest Diagnostics IncorporatedNJClinical Medical Laboratory$111.2M$637.7M
    Bioreference Health, LLCNJClinical Medical Laboratory$66.8M$620.1M
    Laboratory Corporation Of America HoldingsOHClinical Medical Laboratory$56.9M$617M
    Exact Sciences Laboratories, LLCWIClinical Medical Laboratory$299.3M$276.5M
    Laboratory Corporation Of America HoldingsALClinical Medical Laboratory$60.5M$289.1M
    Laboratory Corporation Of AmericaAZClinical Medical Laboratory$38.5M$265.9M

    Nearby Providers

    Other providers in the same ZIP code as Esoterix Genetic Laboratories, LLC, ranked by combined Medicare and Medicaid revenue.

    ProviderStateTaxonomyMedicare RevenueMedicaid Revenue
    Pediatric Services Of America, LLCCTHome Health Agency$0$92.9M
    Adult Day Care Of America, Inc.CTIn Home Supportive Care Agency$0$35.1M
    Dianon Systems, IncCTClinical Medical Laboratory$4.9M$8.5M
    Option Care Enterprises, IncCTHome Infusion Therapy Pharmacy$0$13.3M
    Ameripath New York LLCCTClinical Medical Laboratory$2.9M$7.7M
    Enzo Clinical Labs, Inc.CTClinical Medical Laboratory$0$3.8M
    Bridgeport Radiological Associates LLCCTDiagnostic Radiology Physician$0$2.9M
    Shelton PediatricsCTPediatrics Physician$0$2.7M
    Echo Hose Hook And Ladder Ambulance Corps., Inc.CTLand Ambulance$568.5K$1.7M
    Shelton Dental Group LLCCTDentist$0$2.1M

    Frequently Asked Questions

    References

    1. 1.Medicare Physician & Other Practitioner by Provider and Service. CMS.gov.Provider-level Medicare Part B utilization and payment data.
    2. 2.NPPES NPI Registry. CMS.gov.National Provider Identifier registry used for provider enumeration and taxonomy metadata.

    Trek Health ingests and normalizes Transparency in Coverage data and payer policy updates to give provider organizations a clear view of how commercial reimbursement behaves across markets, payers, and services. Our platform transforms raw payer disclosures into structured intelligence that supports contract evaluation, payer negotiations, and service line strategy. By combining market benchmarks with ongoing policy visibility, Trek helps teams identify variability, risk, and opportunity in commercial reimbursement. The result is faster insight, stronger negotiating positions, and more informed financial decisions.

    Medicare Revenue by CPT/HCPCS Code
    Claims Volume vs. Connecticut Distribution
    Esoterix Genetic Laboratories, LLC — 12 of 25 codes billed far more than typical (above p95)
    p5–p95 (all providers)p25–p75MedianThis providerOutlier
    Rank Distribution — Connecticut
    Medicaid Revenue by Year vs. Connecticut Providers
    0 of 6 years billed far more than typical (above p95)
    p5–p95 (all providers)p25–p75MedianThis providerOutlier
    Claims Volume vs. Connecticut Distribution
    Esoterix Genetic Laboratories, LLC — 5 of 25 codes billed far more than typical (above p95)
    p5–p95 (all providers)p25–p75MedianThis providerOutlier
    Rank Distribution — Connecticut