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    v1.0.28
    OpenPayerBilling CodesPersons with potential health hazards related to communicable diseasesICD-10-CM z29-encounter-for-prophylactic-measures
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    ICD-10-CM Code For Encounter For Other Prophylactic Measures: Group Overview

    The International Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM) code group Z29 includes encounters for other prophylactic measures such as immunizations, passive immunotherapy, and administration of prophylactic agents to prevent communicable diseases and related complications. These ICD-10-CM diagnosis codes are used to document preventive care encounters, capturing the reason for prophylactic intervention and relevant clinical context. Accurate coding within the ICD-10-CM Z29 group supports proper claim adjudication, complete clinical documentation, and appropriate reimbursement.

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    ICD-10-CM Z29: Encounter For Other Prophylactic Measures Overview

    This group represents encounters for prophylactic procedures and measures taken to prevent disease, especially those related to communicable conditions. It targets preventive interventions such as immunizations, passive immunotherapy, and other prophylactic agents or measures. Accurate coding matters because it ensures correct clinical documentation and supports appropriate reimbursement for preventive services.

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    When to Use

    Use a code from this group when the patient encounter is specifically for administration of prophylactic agents or measures rather than treatment of an active infection. Apply these codes to document preventive interventions given due to exposure risk, routine immunization, or other specified prophylactic indications.

    ICD-10-CM Codes

    8 rows

    ICD-10-CM CodeDescription
    Z29.11Encounter for prophylactic immunotherapy for respiratory syncytial virus (RSV)
    Z29.12Encounter for prophylactic antivenin
    Z29.13Encounter for prophylactic Rho(D) immune globulin
    Z29.14Encounter for prophylactic rabies immune globin
    Z29.3Encounter for prophylactic fluoride administration
    Z29.81Encounter for HIV pre-exposure prophylaxis
    Z29.89Encounter for other specified prophylactic measures
    Z29.9Encounter for prophylactic measures, unspecified

    DRG Codes

    1 rows

    DRG CodeDescription
    951Other Factors Influencing Health Status

    Typical Clinical Scenarios

    • An adult travel clinic patient presents for pre-travel evaluation before a two-week mission trip to a region with high risk of meningococcal and hepatitis exposure; no active illness is present but multiple vaccines and immunoglobulin are administered for protection. A code from this group is assigned to indicate the encounter is for prophylactic immunization or passive immunization. Typical codes: Z29.11, Z29.12
    • A newborn in the well-baby nursery receives routine prophylactic eye ointment and a hepatitis B vaccination shortly after birth; there is no infection, but the visit is billed to document the prophylactic measures given to prevent perinatal transmission. A code from this group is used to capture the encounter for those preventive treatments. Typical codes: Z29.13, Z29.14
    • An adult with recent exposure to a confirmed communicable disease arrives at urgent care for administration of post-exposure prophylaxis (e.g., rabies immune globulin or tetanus immune globulin) and counseling; the encounter is focused on preventive treatment following exposure rather than treatment of active disease. A code from this group is assigned to reflect the prophylactic nature of the visit. Typical codes: Z29.3, Z29.81

    Related Codes

    Z20-CONTACT-WITH-SUSPECTED-EXPOSURE

    ICD-10-CM Code For Contact With And (Suspected) Exposure To Communicable Diseases: Group Overview

    Z21-ASYMPTOMATIC-HUMAN-IMMUNODEFICIENCY-VIRUS-INFECTION

    ICD-10-CM Code For Asymptomatic Human Immunodeficiency Virus Infection Status: Group Overview

    Z22-CARRIER-OF-INFECTIOUS-DISEASE

    ICD-10-CM Code For Carrier Of Infectious Disease: Group Overview

    Z23-ENCOUNTER-FOR-IMMUNIZATION

    ICD-10-CM Code For Encounter For Immunization: Group Overview

    Z28-IMMUNIZATION-NOT-CARRIED-OUT

    ICD-10-CM Code For Immunization Not Carried Out And Underimmunization Status: Group Overview

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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