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    v1.0.28
    OpenPayerBilling CodesPersons with potential health hazards related to communicable diseasesICD-10-CM z22-carrier-of-infectious-disease
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    ICD-10-CM Code For Carrier Of Infectious Disease: Group Overview

    The International Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM) code group Z22 includes diagnoses that identify individuals who harbor infectious agents and may transmit communicable diseases despite being asymptomatic or having resolved clinical disease. These ICD-10-CM diagnosis codes are used to document carrier status, prior infection with potential for infectivity, or colonization by specific pathogens, capturing context rather than severity of active disease. Accurate coding within the ICD-10-CM Z22 group supports complete clinical documentation and proper claim adjudication.

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    ICD-10-CM Z22: Carrier Of Infectious Disease Overview

    The ICD-10-CM Z22 group denotes persons identified as carriers of infectious agents who may transmit disease despite lacking active symptoms. These codes target public health and communicable disease surveillance rather than specific organ system pathology. Accurate coding is important for tracking transmission risk, public health reporting, and supporting appropriate reimbursement for related services.

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    When to Use

    Use codes from this group when a clinical assessment or laboratory testing documents carrier status, colonization, or evidence of harboring an infectious organism without active disease. These codes are appropriate for documentation when carrier status affects public health reporting, infection control measures, or care coordination but does not represent an active infectious condition.

    ICD-10-CM Codes

    20 rows

    ICD-10-CM CodeDescription
    Z22.0Carrier of typhoid
    Z22.1Carrier of other intestinal infectious diseases
    Z22.2Carrier of diphtheria
    Z22.31Carrier of bacterial disease due to meningococci
    Z22.321Carrier or suspected carrier of Methicillin susceptible Staphylococcus aureus
    Z22.322Carrier or suspected carrier of Methicillin resistant Staphylococcus aureus
    Z22.330Carrier of Group B streptococcus
    Z22.338Carrier of other streptococcus
    Z22.340Carrier of carbapenem-resistant Acinetobacter baumannii
    Z22.341Carrier of carbapenem-sensitive Acinetobacter baumannii
    Z22.349Carrier of Acinetobacter baumannii, unspecified
    Z22.350Carrier of carbapenem-resistant Enterobacterales
    Z22.358Carrier of other Enterobacterales
    Z22.359Carrier of Enterobacterales, unspecified
    Z22.39Carrier of other specified bacterial diseases
    Z22.4Carrier of infections with a predominantly sexual mode of transmission
    Z22.6Carrier of human T-lymphotropic virus type-1 [HTLV-1] infection
    Z22.7Latent tuberculosis
    Z22.8Carrier of other infectious diseases
    Z22.9Carrier of infectious disease, unspecified

    DRG Codes

    1 rows

    DRG CodeDescription
    951Other Factors Influencing Health Status

    Typical Clinical Scenarios

    • An adult presents to urgent care with acute purulent conjunctivitis after recent close household contact with a person known to have gonococcal eye infection; culture confirms Neisseria gonorrhoeae carriage of the conjunctiva without systemic symptoms. The visit documents asymptomatic bacterial colonization or carrier state identified by testing or exposure history prompting public health notification and counseling. Typical codes: Z22.0, Z22.1
    • A pregnant woman at her first prenatal visit is found on screening to be an asymptomatic carrier of group B Streptococcus in the vagina; she has no active infection but will receive intrapartum prophylaxis. The prenatal chart records colonization status to guide delivery management and neonatal risk reduction, so a carrier/colonization code is assigned. Typical codes: Z22.321, Z22.322
    • An elderly nursing home resident is admitted to the hospital with acute urinary tract infection; review of prior records shows chronic colonization of the urinary tract with multidrug-resistant organisms without active infection between episodes. The admission documents the history of colonization as a comorbidity that may affect isolation and antibiotic choices, warranting a carrier/colonization diagnosis. Typical codes: Z22.8, Z22.9

    Related Codes

    Z20-CONTACT-WITH-SUSPECTED-EXPOSURE

    ICD-10-CM Code For Contact With And (Suspected) Exposure To Communicable Diseases: Group Overview

    Z21-ASYMPTOMATIC-HUMAN-IMMUNODEFICIENCY-VIRUS-INFECTION

    ICD-10-CM Code For Asymptomatic Human Immunodeficiency Virus Infection Status: Group Overview

    Z23-ENCOUNTER-FOR-IMMUNIZATION

    ICD-10-CM Code For Encounter For Immunization: Group Overview

    Z28-IMMUNIZATION-NOT-CARRIED-OUT

    ICD-10-CM Code For Immunization Not Carried Out And Underimmunization Status: Group Overview

    Z29-ENCOUNTER-FOR-PROPHYLACTIC-MEASURES

    ICD-10-CM Code For Encounter For Other Prophylactic Measures: Group Overview

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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